Integration and Bridging of Multiscale Bioengineering Designs and Tissue Biomechanics / edited by Jun Liao, Joyce Y. Wong.

Format:

Book

Contributor:

Liao, Jun., Editor.

Wong, Joyce Y., Editor.

Series:

Biomedical and Life Sciences Series

Language:

English

Subjects (All):

Biomedical engineering.

Regenerative medicine.

Biomechanics.

Biomaterials.

Tissues.

Chemistry.

Biomedical Engineering and Bioengineering.

Regenerative Medicine and Tissue Engineering.

Local Subjects:

Biomedical Engineering and Bioengineering.

Regenerative Medicine and Tissue Engineering.

Biomechanics.

Biomaterials.

Tissues.

Physical Description:

1 online resource (IX, 561 p. 100 illus. in color.)

Edition:

1st ed. 2025.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2025.

Summary:

This book covers up-to-date knowledge of how designs found in nature use tissue hierarchies to achieve optimal functions, and how these principles are applied in bioengineering. The hierarchy-based multiscale approach has the potential to drive novel biomaterial designs, advance tissue engineering and regeneration, assist in tissue-function integration, improve high-fidelity computational modeling aided by machine learning, and enhance the development of innovative characterization tools and methodologies. This book presents the latest high-impact research achievements in bioengineered and natural hierarchical systems within a clinical context. Our aim is two-fold: (i) to emphasize the importance of integrating and bridging bioengineering designs at various tissue hierarchical levels and (ii) to foster dialogue and collaboration among bioengineers, biomechanists, and clinicians. .

Contents:

Mechanical and structural contributions of elastin and collagen fibers to interlamellar bonding in the arterial wall

Tissue engineering of vascular constructs

Engineering the multiscale complexity of vascular networks

Epicardial layer and endocardial layer as mechanical protective interfaces for cardiac function

Dynamic remodeling in live cardiomyocytes

Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture

Multiscale light-sheet for rapid assessing of cardiac architecture and function

Spongiosa as an integrative interface for aortic valve trilayered structure

Advances in experimental and computational biomechanics of the tricuspid heart valve

Heterogeneous and multiscale mechanical behavior of aortic valve leaflets

Multi-scale approach to investigate mechanically-induced changes in tricuspid valve anterior leaflet microstructure

Multiscale Mechanical Considerations for Polymeric Heart Valve Development

The stabilization of elastin network in heart valve tissue engineering

Glutaraldehyde cross-linked mitral valves

Contribution of glycosaminoglycans to tendon mechanical properties

Interfibrillar shear stress as the loading mechanism of collagen fibrils in tendon

Tendon-to-bone Interface: structural-mechanical integration of enthesis

Hierarchical collagen fiber formation for functional tendon, ligament, and meniscus replacement

Tissue-engineered collagen graft using a novel load-bearing suture technique

Tendon/Ligament repair with biomimetic and smart cellular constructs

Tendon/Ligament-Like tissue via three-dimensional cyclic mechanical stretch culture system.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-031-81743-5

OCLC:

1523372765