Mathematical stereochemistry / Shinsaku Fujita.

Format:

Book

Author/Creator:

Fujita, Shinsaku, 1944- author.

Language:

English

Subjects (All):

Chemistry--Mathematics.

Chemistry.

Stereochemistry.

Physical Description:

1 online resource (456 p.)

Place of Publication:

Berlin, Germany : Walter de Gruyter GmbH, [2015]

Language Note:

English

Summary:

Mathematical Stereochemistry uses both chemistry and mathematics to present a challenge towards the current theoretical foundations of modern stereochemistry, that up to now suffered from the lack of mathematical formulations and minimal compatibility with chemoinformatics. The author develops novel interdisciplinary approaches to group theory (Fujita's unit-subduced-cycle-index, USCI) and his proligand method before focusing on stereoisograms as a main theme. The concept of RS-stereoisomers functions as a rational theoretical foundation for remedying conceptual faults and misleading terminology caused by conventional application of the theories of van's Hoff and Le Bel. This book indicates that classic descriptions on organic and stereochemistry in textbooks should be thoroughly revised in conceptionally deeper levels. The proposed intermediate concept causes a paradigm shift leading to the reconstruction of modern stereochemistry on the basis of mathematical formulations. • Provides a new theoretical framework for the reorganization of mathematical stereochemistry. • Covers point-groups and permutation symmetry and exemplifies the concepts using organic molecules and inorganic complexes. • Theoretical foundations of modern stereochemistry for chemistry students and researchers, as well as mathematicians interested in chemical application of mathematics. Shinsaku Fujita has been Professor of Information Chemistry and Materials Technology at the Kyoto Institute of Technology from 1997-2007; before starting the Shonan Institute of Chemoinformatics and Mathematical Chemistry as a private laboratory.

Contents:

Front matter

Preface

About the author

Contents

1 Introduction

2 Classification of Isomers

3 Point-Group Symmetry

4 Sphericities of Orbits and Prochirality

5 Foundations of Enumeration Under Point Groups

6 Symmetry-Itemized Enumeration Under Point Groups

7 Gross Enumeration Under Point Groups

8 Enumeration of Alkanes as 3D Structures

9 Permutation-Group Symmetry

10 Stereoisograms and RS-Stereoisomers

11 Stereoisograms for Tetrahedral Derivatives

12 Stereoisograms for Allene Derivatives

13 Stereochemical Nomenclature

14 Pro-RS-Stereogenicity Based on Orbits

15 Perspectives

Index

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on print version record.

ISBN:

9781523104604

1523104600

9783110386370

3110386372

9783110366693

311036669X

OCLC:

918555681