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Basic mechanisms of the epilepsies : molecular and cellular approaches / editors, Antonio V. Delgado-Escueta [and others].
Holman Biotech Commons Per.
Mixed Availability
- Format:
- Book
- Conference/Event
- Conference Name:
- International Symposium on Basic Mechanisms of the Epilepsies (1983 : San Diego, Calif.)
- Series:
- Advances in neurology ; v. 44.
- Advances in neurology ; v. 44
- Language:
- English
- Subjects (All):
- Epilepsy--Congresses.
- Epilepsy.
- Pathology, Molecular--Congresses.
- Pathology, Molecular.
- Pathology, Cellular--Congresses.
- Pathology, Cellular.
- Medical Subjects:
- Epilepsy.
- Genre:
- Kongress -- San Diego (Calif.) -- 1982.
- Conference papers and proceedings.
- Physical Description:
- xxiv, 1096 pages : illustrations ; 27 cm.
- Place of Publication:
- New York : Raven Press, 1986.
- Language Note:
- Based on workshops held at the Kroc Foundation headquarters in Calif. in Dec. 1982 and during the International Symposium on Basic Mechanisms of the Epilepsies, held in San Diego, Dec. 1983; both sponsored by the Subcommittee on Basic Research of the Epilepsy Advisory Committee, National Institute of Neurological and Communicative Disorders and Stroke.
- Contents:
- New wave of research in the epilepsies
- Genetic heterogeneity in the epilepsies
- Looking for epilepsy genes: clinical and molecular genetic studies
- Mutational analysis of inherited epilepsies
- Inherited convulsive disorders in mice
- Voltage-dependent currents of vertebrate neurons and their role in membrane excitability
- Toward a mechanism of gating of chemically activated channels
- Conducting sites in excitable membranes
- Modulators acting on sodium and calcium channels: patch-clamp analysis
- Role of persistent inward and outward membrane currents in epileptiform bursting in mammalian neurons
- Membrane currents underlying bursting pacemaker activity and spike frequency adaptation in invertebrates
- Control theory applied to neural networks illuminates synaptic basis of interictal epileptiform activity
- Mechanisms of interictal epileptogenesis
- Kindling model of epilepsy
- Failure of GABAergic inhibition: a key to local and global seizures
- Role of the substantia nigra in GABA-mediated anticonvulsant actions
- Benzodiazepine/barbiturate/GABA receptor-chloride ionophore complex in a genetic model for generalized epilepsy.
- Gaba receptors, lipids, and gangliosides in cobalt epileptic focus
- Roles of biogenic amines and cyclic nucleotides in seizure mechanisms
- Long-term potentiation and kindling: similar biochemical mechanisms?
- Synaptic mechanisms in the kindled epileptic focus: a speculative synthesis
- Molecular approach to the calcium signal in brain: relationship to synaptic modulation and seizure discharge
- Cerebral methylations in epileptogenesis
- Role of noradrenergic ascending system in extinction of epileptic phenomena
- Neuropeptides: anticonvulsant and convulsant mechanisms in epileptic model systems and in humans
- Opioid peptides and epileptogenesis in the limbic system: cellular mechanisms
- Spread and arrest of seizures: the importance of layer 4 in laminar interactions during neocortical epileptogenesis
- Temporal and spatial distribution of intracellular potentials during generation and spread of epileptogenic discharge
- Cellular basis of neuronal synchrony in epilepsy
- Role of electrical interactions in synchronization of epileptiform bursts
- Ionic changes and alterations in the size of the extracellular space during epileptic activity
- Extracellular calcium and potassium concentration changes in chronic epileptic brain tissue
- Interstitial ion concentrations and paroxysmal discharges in hippocampal formation and spinal cord.
- Na+, K+-ATPase: structure, function, and interactions with drugs
- Role of glial cation and anion transport mechanisms in etiology and arrest of seizures
- Anticonvulsant drugs: mechanisms of action
- Contemporary methods in neurocytology and their application to the study of epilepsy
- Freeze-fracture studies of plasma membranes of astrocytes in freezing lesions
- Structural substrates of epilepsy
- Epilepsy and the blood-brain barrier
- Epileptic brain damage: pathophysiology and neurochemical pathology
- Cell damage in epilepsy and the role of calcium in cytotoxicity
- Excitotoxic mechanisms of epileptic brain damage
- Accumulation of free arachidonic acid, diacylglycerols, prostaglandins, and lipoxygenase reaction products in the brain during experimental epilepsy
- Brain protein metabolism in epilepsy
- identification of seizure-mediating brain structures with the deoxyglucose method: studies of human epilepsy with positron emission tomography, and animal seizure models with contact autoradiography
- Regional cerebral blood flow and metabolic rates in human focal epilepsy and status epilepticus
- Neuronal, dendritic, and vascular profiles of human temporal lobe epilepsy correlated with cellular physiology in vivo
- Neuronal firing patterns from epiletogenic foci on monkey and human
- Hippocampal slices in experimental and human epilepsy
- Amino acid and catecholamine markers of metabolic abnormalities in human focal epilepsy
- Alterations of GABA-mediated synaptic transmission in human epilepsy
- Neuron-glia relationships in human and experimental epilepsy: a biochemical point of view.
- Notes:
- Based on workshops held at the Kroc Foundation headquarters in Calif. in Dec. 1982 and during the International Symposium on Basic Mechanisms of the Epilepsies, held in San Diego, Dec. 1983; both sponsored by the Subcommittee on Basic Research of the Epilepsy Advisory Committee, National Institute of Neurological and Communicative Disorders and Stroke.
- Includes bibliographical references and index.
- Other Format:
- Online version: Basic mechanisms of the epilepsies.
- ISBN:
- 0881671525
- 9780881671520
- OCLC:
- 12838100
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