Families at high risk for depression : a forty year study / edited by Myrna M. Weissman and Connie Svob

Format:

Book

Contributor:

Weissman, Myrna M., editor.

Svob, Connie, editor.

Language:

English

Subjects (All):

Depression, Mental--Risk factors.

Depression, Mental.

Families--Health and hygiene.

Families.

Family Health.

Medical Subjects:

Family Health.

Physical Description:

1 online resource : illustrations

illustration

Place of Publication:

New York, NY : Oxford University Press, [2026]

Summary:

"The results of a 40-year three-generation study of families at high and low risk for major depression are presented. Clinical outcomes, including diagnosis, medical, and social functioning, with case descriptions, as well as preliminary efforts to understand brain functioning using electrophysiology and magnetic resonance imaging are presented. The roles of religion/spirituality as protections for some individuals is described. The clinical samples include the biological offspring and the grandchildren of the first generation high (depressed) or low risk (not depressed) probands. The clinical findings on the offspring and grandchildren are considered in light of our current understanding from animal model studies as well as their final implementation and translation in larger populations. The study began when there was limited research on clinical depression. Now with a rich understanding of the presentation and course of depression, future directions of research and clinical care are considered. Included are discussion of early detection, prevention, and treatment. The limitations of this study include its lack of social diversity and the fact that genetic studies are limited as efforts to replicate findings in separate studies, including large diverse samples. The next phase of research is diverse, rich, and promising"-- Oxford Academic

Contents:

Background and personal overview / Myrna M. Weissman

Our research methods / Connie Svob and others

The offspring of depressed parents: Clinical findings / Stephanie Kasen and others

The grandchildren of depressed parents: Clinical findings / Stephanie Kasen and Tenzin Yangchen

Medical conditions and cognition / Syed Muhammad Ahsan Mehdi and others

Religion and spirituality / Connie Svob and others

Electrophysiology and functional laterality / Jürgen Kayser and Gerard E. Bruder

Magnetic resonance imaging / Ardesheer Talati and others

Translational insights: Animals to people to populations / Milenna T. Van Dijk and others

A way forward: Implications for prevention and treatment / Myrna M. Weissman and Connie Svob

Notes:

Includes bibliographical references and index

Online resource; title from home page (Oxford Academic, viewed September 18, 2026)

Other Format:

Print version: Families at high risk for depression

ISBN:

9780197821435

019782143X

9780197821411

0197821413

OCLC:

1599575764

Publisher Number:

CIPO000408928

Access Restriction:

Some versions: Open access versions available from some providers open access