Handbook of Parkinson's disease mechanisms edited by Rosario Moratalla, Mario Gustavo Murer

Format:

Book

Contributor:

Moratalla, Rosario, editor.

Murer, Mario Gustavo, editor.

Series:

Handbook of behavioral neuroscience v. 35

Handbook of behavioral neuroscience volume 35

Language:

English

Subjects (All):

Parkinson's disease--Handbooks, manuals, etc.

Parkinson's disease.

Genre:

Handbooks and manuals

Physical Description:

1 online resource

Place of Publication:

London, United Kingdom Academic Press 2025

Summary:

Offers an integrated overview of the fundamental research devoted to understanding its causes and mechanisms, highlighting recent advances and clinical significance.?With a strong focus on cellular and animal model studies, this book also examines the etiology, pathophysiology, epidemiology and underlying symptoms of Parkinson's disease. Written with an interdisciplinary approach, this book provides thorough research that will be of interest to researchers, clinicians and graduate students interested in neurodegenerative diseases

Contents:

Cross-talk between genetic and environmental factors in Parkinson's disease / Pierre-Olivier Fernagut, Benjamin Dehay

Neuromelanin: bridging catecholamine metabolism and neurodegeneration in Parkinson's disease / Marta Gonzalez-Sepulveda, Joana M. Cladera-Sastre, Miquel Vila

Rodent models for exploring the mechanisms contributing to Parkinson's disease pathophysiology / Joseph Allison, Susan Duty

Non-human primate models of Parkinson's disease and related synucleinopathies / Julia Chocarro, José L. Lanciego

Alpha-synuclein spreading in Parkinson's disease / Chengyuan Song, Kelvin Luk

The role of mitochondria in the pathogenesis of Parkinson's disease / S. Koletsi, G. Uras, A.H.V. Schapira

Parkinson's disease: a chronic systemic inflammatory disorder / Hina Khan, Matthew J. Benskey

Transcription factor NRF2: new therapeutic approach to modify Parkinson's disease progression / Ana I. Rojo, Noemí Esteras, Antonio Cuadrado, Isabel Lastres-Becker

Dopamine neurotransmission in Parkinson's disease / Kaitlyn M.L. Cramb, Humaira Noor, Richard Wade-Martins, Stephanie J. Cragg

Morphological plasticity of striatal medium spiny neurons: its potential contribution to Parkinson's disease pathophysiology / Rosa M. Villalba, Yoland Smith

Network determinants of motor disability in Parkinson's disease / Qiaoling Cui, Shenyu Zhai, DeNard V. Simmons, Dalton James Surmeier

Molecular mechanisms of l-DOPA-induced dyskinesia / M. Angela Cenci, Juan Ferrario

Cholinergic contributions to Parkinsonian symptoms and l-DOPA-induced dyskinesia / Cecilia Tubert, Rodrigo Manuel Paz, Agostina Mónica Stahl, Mario Gustavo Murer

Role of the raphe-serotonin system in Parkinson's disease: compensatory versus maladaptive plasticity / Ashley Galfano, Kuei Tseng, Fredric Manfredsson, Christopher Bishop

Two-factor model of l-DOPA-induced dyskinesia: bridging early clinical findings with modern mechanistic understanding / Mario Gustavo Murer, Rosario Moratalla

Network dynamics in rodent models of Parkinson's disease / Per Petersson, Judith R. Walters

Reevaluating the role of the STN-GPe network in generating beta synchronized oscillatory activity in parkinsonism / Brice De la Crompe, Marc Deffains, Arthur Leblois, Nicolas Mallet

Network dynamics in Parkinson's disease: primate models and patients / Jing Wang, Luke A. Johnson, Jerrold L. Vitek, Joshua E. Aman

Cell replacement and gene therapies for Parkinson's disease: a precision medicine framework / Carlye Szarowicz, Asha Savani, Timothy J. Collier, Kathy Steece-Collier

The cerebellum in Parkinson's disease and levodopa-induced dyskinesia: from neural mechanisms to therapeutic interventions / Marie Sarraudy, Daniela Popa

Role of cerebellum in Parkinson's disease symptoms / Andrés Pablo Varani, Maria Camila Bagliani, Malco Damian Rossi

Brainstem origin of Parkinson's disease symptoms / Angela Isabel Tissone, Maria Soledad Esposito

Notes:

Includes bibliographical references and index

Online resource; title from PDF title page (ScienceDirect, viewed November 20, 2025)

OCLC:

1552805727

Access Restriction:

Restricted for use by site license