Protein misfolding in neurodegenerative diseases edited by Neha Gogia, Sandeep Kumar Singh and Vidyadhara Devarunda Jaganath

Format:

Book

Contributor:

Gogia, Neha, editor.

Singh, Sandeep Kumar, editor.

Devarunda Jaganath, Vidyadhara, editor.

Language:

English

Subjects (All):

Nervous system--Degeneration--Molecular aspects.

Nervous system.

Protein folding.

Physical Description:

1 online resource

Place of Publication:

London Academic Press 2025

Summary:

Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, ALS, Creutzfeldt-Jakob disease, and more

Notes:

Online resource; title from PDF title page (ScienceDirect, viewed March 19, 2025)

OCLC:

1509755703

Access Restriction:

Restricted for use by site license