Fundamentals of brain organoids for neurological diseases edited by Balachandar Vellingiri, Mahalaxmi Balachandar

Format:

Book

Contributor:

Vellingiri, Balachandar, editor.

Balachandar, Mahalaxmi, editor.

Language:

English

Subjects (All):

Nervous system--Diseases--Treatment.

Nervous system.

Induced pluripotent stem cells--Therapeutic use.

Induced pluripotent stem cells.

Nervous system--Diseases.

Organoids.

Nervous System Diseases.

Medical Subjects:

Organoids.

Nervous System Diseases.

Physical Description:

1 online resource

Place of Publication:

London, U.K. Cambridge, MA Academic Press [2026]

Summary:

Researchers use brain organoids to study the formation of neural tissues, investigate the processes involved in brain development, and gain a better understanding of neurological disorders and diseases. Brain organoids are particularly useful in studying developmental disorders, neurodegenerative diseases, and infectious diseases that affect the brain. This book provides a practical resource for researchers on how to utilize and apply brain organoids. This book is organized into nine distinct sections, guiding the reader through each step from advanced overview of what organoids are to the use of brain organoids in various neurodevelopmental disorders and neurodegenerative diseases. In later sections, this book reviews the necessary methods involved in organoid development including the elements and challenges involved. This book will serve as a valuable tool for researchers, helping to advance the understanding of brain biology and disease mechanisms

Contents:

An overview on organoids

past, present, and future scenarios of organoids / Mahalaxmi Iyer

A brief introduction to neurodevelopmental disorders / Panimalar Abirami Karuppusamy, Deenathayalan Uvarajan, Masako Kinoshita

Use of brain organoids for autism / Ajay Elangovan, Nitin Kumar, Tanja Maria Michel

Role of brain organoids in Rett syndrome / Mohan Gomathi, Pooparambil Vishnupriya

Brain organoids in bipolar disorder: unraveling mechanisms and therapeutic approaches / Souradip Chaterjee, Laxmi Kirola

Ongoing clinical trials on use of brain organoids for neurodevelopmental disorders / Bilal Rather, Pragati Kumari, Suryanarayan Biswal

An overview of neurodegenerative diseases / Sindduja Muthukumar, Harysh Winster Suresh Babu, Mohana Devi Subramaniam

Use of brain organoids for Parkinson's disease and Alzheimer's diseases / Sneha Kumari, Prajjwal Sharma, Dibbanti HariKrishnaReddy

Application of brain organoids in Huntington's disease / Roselin Gnanarajan, Nandita Ravichandran, Arul Narayanasamy

Use of brain organoids for neurodegenerative diseases (Alzheimer's disease, Parkinson's disease, Huntington's disease, et cetera) / Ankit Kumar Bharti S, Deepthi Maria Mathew, Abilash Valsala Gopalakrishnan

How human-induced pluripotent stem cells are derived into organoids / Harysh Winster Suresh Babu, Nandhini Ilangovan, Ravimanickam Thangarasu

Elements required and days involved in organoid generation / Vignesh Palanivel, Khushboo Chauhan, Mukesh Kumar Yadav

Brain organoids - Challenges while constructing organoids / Sudharsan Parthasarathy, Bupesh Giridharan, Longnyu Konyak

Existing drug targeting and research using brain organoids / Padmanabh Singh, Mayuri Varma, Rakhi Pal

Ethical considerations while conducting organoids research / Jeyavel Sundaramoorthy, Parthasarathy, Vijyendra Pandey

Future directions and conclusion / Balachandar Vellingiri, Jyoti Parkash, Mahalaxmi Iyer

Notes:

Includes bibliographical references and index

ISBN:

9780443298998

0443298998

OCLC:

1545277085

Access Restriction:

Restricted for use by site license