Carbon and graphene quantum dots for biomedical applications / Kyusik Yun and Saravanan Govindaraju, editors.

Format:

Book

Author/Creator:

Yun, Kyusik

Contributor:

Yun, Kyusik, editor.

Govindaraju, Saravanan, editor.

Series:

Woodhead Publishing Series in Biomaterials Series

Language:

English

Subjects (All):

Biomedical materials.

Medical electronics.

Quantum dots.

Quantum Dots.

Biomedical Technology.

Biomedical and Dental Materials.

Electronics, Medical.

Graphite.

Carbon.

Medical Subjects:

Quantum Dots.

Biomedical Technology.

Biomedical and Dental Materials.

Electronics, Medical.

Graphite.

Carbon.

Physical Description:

1 online resource (320 pages)

Edition:

1st ed.

Place of Publication:

Cambridge, MA : Elsevier Ltd., [2023]

Summary:

Carbon and Graphene Quantum Dots for Biomedical Applications provides a single point of reference for understanding the biomedical potential of quantum dots.The book covers the synthesis and properties of various carbon and graphene quantum dots, with advanced discussion on the challenges faced during synthesis according to type, structure, size.

Contents:

Intro

Carbon and Graphene Quantum Dots for Biomedical Applications

Copyright

Contents

Contributors

Preface

Acknowledgments

Chapter 1: Fundamentals of carbon and graphene quantum dots

1.1. Introduction

1.2. Synthetic approaches to carbon and graphene quantum dots

1.2.1. Bottom-up methods

1.2.1.1. Microwave-assisted synthesis

1.2.1.2. Hydrothermal/solvothermal strategy

1.2.1.3. Thermal pyrolysis

1.2.2. Top-down methods

1.3. Characterization techniques for CQDs and GQDs

1.4. Properties of carbon and graphene quantum dots

1.5. Conclusion and future perspectives

References

Chapter 2: Carbon quantum dots biosynthesis: Perspectives and challenges

2.1. Introduction

2.2. Physical and chemical synthesis of CQDs

2.3. Biosynthesis of CQDs

2.3.1. Chemical oxidation

2.3.2. Ultrasonication

2.3.3. Microwave-assisted carbonization

2.3.4. Hydrothermal/solvothermal

2.3.5. Thermal decomposition

2.3.6. Pyrolysis

2.4. Challenges and future perspectives

2.5. Conclusion

Chapter 3: The era of graphene-based quantum dots

3.1. Introduction

3.2. Synthesis of CQDs and GQDs

3.2.1. Synthesis of CQDs

3.2.1.1. Top-down approach

3.2.1.2. Bottom-up approach

3.2.2. Synthesis of GQDs

3.2.2.1. Top-down approach

3.2.2.2. Bottom-up approach

3.3. Properties of CQDs and GQDs

3.3.1. Optical properties

3.3.2. Biological properties

3.4. Limitations

3.4.1. Toxicity

3.4.2. Biodistribution

3.5. Biological applications

3.5.1. Drug delivery

3.5.2. Cancer therapy

3.5.3. Phototherapy

3.5.3.1. Photothermal therapy

3.5.3.2. Photodynamic therapy

3.5.4. Gene therapy

3.6. Conclusion

Chapter 4: Quantum dots conjugation and its advancement in biomedical applications

4.1. Introduction.

4.2. Quantum dots conjugation

4.3. Covalent conjugation

4.3.1. Amine group conjugation

4.3.2. Carboxylic acid conjugation

4.3.3. Epoxide group conjugation

4.3.4. Aldehyde and hydroxy groups conjugation

4.3.5. Thiol group conjugation

4.4. Electrostatic interaction

4.5. Click chemistry

4.6. Dative conjugation

4.7. Biomedical applications

4.7.1. Bioimaging and labeling

4.7.2. Quantum dots biosensors and bio barcodes

4.7.3. Cancer therapy and drug delivery

4.8. Conclusion

Chapter 5: Recent advancements of carbon quantum dots for biological applications

5.1. Effects of carbon dots on microorganisms

5.2. Carbon quantum dots

5.3. Combination with other antimicrobial reagents

5.4. Novel targets with new antimicrobial agents

5.4.1. Cell wall target

5.5. Novel membrane-targeting antimicrobial agents

5.6. Fatty acid biosynthesis inhibitor

5.7. Chorismate biosynthesis inhibitor

5.8. Isoprenoid biosynthesis inhibitor

5.9. Disruption of resistant genes

5.10. Conclusion

Chapter 6: Emerging trends of quantum dots in detection and treatment of animal viruses

6.1. Introduction

6.1.1. Treatment

6.2. Overview of quantum dot synthesis, structure, types, properties, and biomedical applications

6.2.1. Synthesis of quantum dots (QDs)

6.2.2. Properties

6.2.3. Biomedical applications

6.2.3.1. Fluorescence-based GQD sensors

6.2.3.2. Quantum dots (QDs) in tumor research

6.2.3.3. Photodynamic therapy (PDT)

6.2.3.4. Targeted drug delivery

6.2.3.5. Quantum dots in the detection of viral diseases: modes of action

6.2.3.6. Recent trends of quantum dots in detection and treatment of viral diseases

6.3. Limitations

6.4. Conclusion and future prospective

Chapter 7: Quantum dots as antibacterial agents.

7.1. Introduction

7.2. CQDs as antibacterial agents

7.2.1. CDs as bactericidal agents

7.2.2. CDs eradicate biofilm

7.2.3. CDs as drug delivery carriers

7.2.4. Photodynamic therapy using CDs

7.3. Conclusion

Chapter 8: Quantum dots: Emerging trends toward biosensing

8.1. Introduction to quantum dots

8.2. Carbon dots

8.3. Graphene dots

8.4. Properties

8.4.1. Absorption property

8.4.2. Emission property

8.4.3. Electrical property

8.5. Various applications of GQDs

8.5.1. Supercapacitor

8.5.2. Lithium-ion batteries

8.5.3. Photo sensors

8.6. Different hetero structures

8.6.1. UV photo detectors

8.6.2. Broadband photo detectors

8.6.3. Hetero structured solar cells

8.6.4. Light emitting diodes

8.6.5. Flexible and wearable electronic devices

8.7. Hydrogen fuels

8.8. Biosensors

8.8.1. Micro RNA detection

8.8.2. Electrochemical biosensors

8.8.3. Optical biosensors

8.8.4. Enzymatic biosensors

8.8.5. Antigen-antibody biosensors

8.8.6. Nucleic acid biosensors

8.8.7. Electrochemical enzymatic biosensors

8.8.8. Electrochemical affinity biosensors

8.9. Biosensors for glucose

8.9.1. Electrochemical immune sensors

8.9.2. Aptasensors

8.9.3. Cyto sensors

8.9.4. Amperometric sensors

8.9.5. Conductometric sensors

8.9.6. Impedimetric sensors

8.9.7. Humidity sensors

8.9.8. Gas sensors

8.10. Conclusion

Chapter 9: Quantum dots-based pathogenic biosensing

9.1. Introduction

9.2. Quantum dots

9.2.1. Carbon QDs

9.2.2. Colloidal QDs

9.3. Feasible mechanism of pathogenic sensing

9.3.1. Antigen-antibody interaction

9.3.2. Affinity-based approach

9.3.3. Aptamer-based approach

9.4. Biosensing techniques

9.4.1. Optical sensors

9.4.2. Electrochemical sensors

9.4.3. Quartz crystal microbalance.

9.4.4. e-Nose

9.5. Outlook and future perspectives

9.6. Conclusion

Chapter 10: Detection of biomolecules and body fluid by using quantum dots

10.1. Introduction

10.1.1. Biomolecules and body fluids

10.1.2. Graphene/carbon-based quantum dots

10.1.3. Understanding SERS

10.2. SERS sensing of biomolecules through graphene/carbon-based quantum dot composites

10.3. Conclusion

Chapter 11: Quantum dots: Synthesis techniques and its importance in biomedical field

11.1. Introduction

11.2. Synthesis methods

11.2.1. Wet-chemical method

11.2.2. Vapor-phase method

11.2.3. Hot injection

11.2.4. Water-in-oil method

11.2.5. Sol-gel method

11.2.6. Pyrolysis method

11.3. Carbon quantum dots

11.3.1. Introduction

11.3.2. Synthesis methods for CQDs

11.3.2.1. Hydrothermal synthesis of carbon quantum dots

11.3.2.2. Photoluminescent CQDs

11.3.2.3. Microwave irradiation

11.4. Application

11.4.1. Cancer therapy and drug delivery

11.4.2. Bio imaging

11.4.3. Antimicrobial activity

11.5. Limitations and drawbacks

11.6. Conclusion

Chapter 12: Trends and developments in point-of-care diagnostics using quantum dots

12.1. Introduction

12.2. Synthesis of carbon quantum dots

12.3. Properties of graphene and carbon quantum dots

12.4. The need for and importance of point-of-care diagnostics

12.4.1. Fluorescence property of carbon quantum dots used in POC

12.4.2. Liquid phase sensing

12.4.2.1. Determination of bio-molecules

12.4.2.2. Determination of vitamin B12

12.4.2.3. Determination of glucose

12.4.2.4. Determination of dopamine in human urine

12.4.2.5. Determination of hemoglobin in human blood samples

12.4.2.6. Determination of bacteria and cancer cells

12.4.2.7. Determination of cholesterol.

12.4.2.8. Determination of DNA

12.4.2.9. Anti-aging agent

12.4.3. Solid phase sensing

12.4.3.1. Test paper sensing

Determination of toxic heavy metals

Carbon quantum fibers produced by the electrospinning method

Food additives detection

12.4.4. Hydrogels

12.4.5. Cytotoxicity of carbon-based quantum dots

12.4.6. Bio-imaging applications

12.4.6.1. Magnetic resonance imaging

12.4.6.2. Dual model imaging

12.5. Conclusions

Chapter 13: Therapeutic and imaging applications of quantum dots

13.1. Introduction

13.2. Carbon quantum dots

13.2.1. Synthesis of carbon quantum dots by hydrothermal and solvothermal methods

13.2.2. Synthesis of carbon quantum dots by electrochemical oxidation

13.2.3. Synthesis of carbon QDs by laser ablation technique

13.2.3.1. Microwave pyrolysis mode of synthesis

13.2.3.2. Oxidative acid treatment

13.3. Carbon quantum dots for bioimaging

13.3.1. Functionalized carbon quantum dots for detection of bacteria and tumor cells

13.3.2. Synthesis of carbon QDs and mannose carbon QDs

13.3.3. Carbon quantum dots by hyaluronan-conjugate for bioimaging use

13.4. Graphene quantum dots

13.4.1. Top-down approach

13.4.2. Synthesis of GQDs by bottom-up techniques

13.4.3. Chemical oxidation method

13.4.4. Hydrothermal method

13.4.5. Electrochemical oxidation technique

13.4.6. Microwave-assisted technique

13.4.7. Graphene quantum dots for targeting drug delivery and synergistic chemophotothermal therapy

13.4.8. GQDs nanocomposite for in vivo theranostic applications

13.4.9. Multi-fluorescent GQDs derived from milk (natural compound) for cancer theranostic systems

Chapter 14: Innovations and applications of quantum dots for cancer therapy

14.1. Introduction

14.2. Carbon quantum dots.

14.3. Carbon quantum dots with unique properties.

Notes:

Includes bibliographical references and index.

Description based on print version record.

Description based on publisher supplied metadata and other sources.

Other Format:

Print version: Yun, Kyusik Carbon and Graphene Quantum Dots for Biomedical Applications

ISBN:

9780323985253

9780323983624

0323983626

0323985254

OCLC:

1385453398