Antibiotics and Reproductive Health.

Format:

Book

Author/Creator:

Rao, Faiza.

Contributor:

Rao, Anam.

Language:

English

Physical Description:

1 online resource (225 pages)

Edition:

1st ed.

Place of Publication:

Sharjah : Bentham Science Publishers, 2025.

Summary:

Antibiotics and Reproductive Health explores the intricate interplay between antibiotics and the female reproductive system. This comprehensive volume offers an evidence-based analysis of how antibiotics impact fertility, pregnancy, and breastfeeding, with a special focus on antibiotic resistance and emerging treatment alternatives. Bridging medicine, pharmacology, and reproductive health, the book is structured into nine chapters covering topics from the mechanism of antibiotics in reproductive health to alternative therapies like probiotics and herbal medicine. It provides clinical guidelines and discusses risks such as antibiotic resistance and microbiome disruption. Key Features: - Detailed exploration of antibiotic mechanisms in reproductive health. - Discussion on risks including antibiotic resistance and hormonal effects. - Examination of alternative therapies like probiotics and herbal medicine. - Clinical guidelines for antibiotic use in reproductive health.

Contents:

Intro

Title

Copyright

End User License Agreement

Contents

Foreword

Preface

List of Contributors

Introduction to Antibiotics and Female Reproductive Health

Z. Maryam1, J. Asma1,*, Hoor ul A.1, H. Maham1 and Sumaira Kanwal2

INTRODUCTION

Antibiotics and Their Role in Healthcare

Importance of Female Reproductive Health

Significance of Understanding Antibiotic Effects on Female Reproductive Health

MECHANISM OF ACTION OF DIFFERENT TYPES OF ANTIBIOTICS

Purpose of Antibiotics

Some Commonly Used Antibiotics and Their Mechanisms of Action

Penicillins

Bacterial Resistance and Beta-lactamase

Mechanism of Action: Cell Wall Construction

Cross-Linking in Bacterial Cell Walls

Tipper-Strominger Hypothesis and Penicillin Binding

Gram-positive and Gram-negative Bacteria

Cephalosporins

Macrolides

Amino Glycosides

Quinolone

Ciprofloxacin Activity and Bacterial Growth Rates

Effects of Elevated Concentrations

Induction of Apoptosis-like Cell Death

Sulfa Drugs

Role of Para-Aminobenzoic Acid (PABA)

Inhibition of Folic Acid Synthesis

Formation of Pseudometabolites

Synergistic Effects of Trimethoprim

FEMALE REPRODUCTIVE HEALTH

Common Reproductive Health Issues in Women

Anatomical Susceptibility in Women

Effects of STIs on the Female Reproductive Tract

Pathogens Responsible for STIs

Importance of Screening and Treatment

Prioritizing Women's Reproductive Health

Antibiotic Treatment for Reproductive Health Issues

UTI Treatment

Increased Risk Factors

Estrogen Replacement Therapy

Clinical Findings

BV Treatment

Treatment Protocols

Tinidazole: A Second-Generation Nitroimidazole

Alternative Treatments

PID Treatment

Empiric Broad-Spectrum Coverage

Macrolides vs. Tetracyclines in Clinical Treatment

STI Treatment.

Treatment Regimens for Chancroid

Treatment Regimens for Gonorrhea

Treatment Regimens for Syphilis

Treatment Regimens for Genital Herpes

STI Treatment During Pregnancy

Potential Side Effects of Antibiotics on Female Reproductive Health

Disruption of Vaginal Microbiota

Increased Risk of Yeast Infections

Development of Antibiotic Resistance

Impact on Hormonal Contraceptives

PRESCRIBING GUIDELINES FOR REPRODUCTIVE HEALTH ISSUES

INDIVIDUALIZED TREATMENT PLANS AND CONSIDERATIONS

Tailoring Antibiotics to the Specific Infection

Dosage and Duration of Antibiotic Treatment

Alternative Treatments to Broad Spectrum Antibiotics

STRATEGIES TO MINIMIZE THE IMPACT OF ANTIBIOTICS ON REPRODUCTIVE HEALTH

Probiotics and their Role in Maintaining Vaginal Health

Importance of Proper Hygiene Practices

Feminine Hygiene and Intimate Health

Use of Medically Approved Products

Impact of Hygiene Practices on Health

Prevention Measures for Sexually Transmitted Infections

FUTURE PERSPECTIVES

CONCLUSION

REFERENCES

Understanding The Reproductive System

Faiza Rao1,* and Anam Rao2

Ovaries

The Primary Female Reproductive Organs

Oogenesis

The Development of Female Gametes

Development of Ovarian Follicles and Ovulation

Two Phases of the Ovarian Cycle

Follicular Phase

Luteal Phase

Fallopian Tubes

Oocyte Transport

Uterus

Vagina

External Genitalia

Female Sexual Response and Hormone Control

Mammary Glands

Menstrual Cycle

Hormonal Control of Menstrual Cycle

How Antibiotics Work?

Hina Aftab1,*, Ayesha Ahmed Sumra2, Fakhr-un-Nisa2, Mahrukh Ali2, Nimra Ali2 and Anam Rao3

IMPORTANCE OF ANTIBIOTICS IN REPRODUCTIVE HEALTH

Potential Side Effects and Risks.

Importance of Proper Antibiotic Administration

REPRODUCTION

Types of Reproduction

Asexual Reproduction

Types of Asexual Reproduction

Binary Fission

Budding

Vegetative Propagation

Fragmentation

Parthenogenesis

Spore Formation (Sporogenesis)

Apomixes

Sexual Reproduction

Sexual Selection

Reproductive System

Human Reproductive System

Male Reproductive System

STAGES OF REPRODUCTION

Pre-fertilization

Fertilization

Post-fertilization

Common Reproductive Health Issues

Endometriosis

Uterine Fibroids

Gynecologic Cancer

HIV (Human Immunodeficiency Virus)

Interstitial Cystitis

Polycystic Ovary Syndrome

Antibiotics and Reproduction

Antibiotics and Fertility

Impact of Antibiotics on Sperm Health

Effects of Antibiotics on Female Fertility

Antibiotics and Sexually Transmitted Infections

Antibiotics for Treating Common STIs

Antibiotics and the Threat of Miscarriage

Antibiotics and Pregnancy

Antibiotics before Pregnancy

Antibiotics used During Pregnancy

Antibiotic Safety in Several Trimesters

Avoiding Certain Antibiotics

Antibiotics used for Treating Maternal Infections

Antibiotics and Assisted Reproductive Technologies (ART)

Assisted Reproductive Technologies (ART)

Role of Antibiotics in ART Procedures

Antibiotic Prophylaxis in in vitro Fertilization (IVF)

Reducing the Risk of Infection in ART

Antibiotics and Fertility Preservation

Antibiotic Protocols for Egg and Sperm Freezing

Preventing Infections During Cryopreservation

Precautions in Antibiotic use during Reproduction

Safety of Antibiotics during Pregnancy

Challenges and Considerations

Limitations and Controversies in Antibiotic use for Reproductive Health

Challenges in using Antibiotics for Reproduction

Disruption of Normal Microbiota.

Alterations in the Vaginal Microbiome

Antibiotic Resistance

Complications in Pregnancy

Vertical Transmission

Treatment Challenges

Impact on Assisted Reproductive Technologies (ART)

Side effects and Adverse Reactions

Challenge of Selection of Appropriate Antibiotics in Reproduction System

Research and Development

Combination Therapy

Antimicrobial Stewardship

Supportive Care and Monitoring

Pregnancy and Antibiotics

Tehmina Siddique1,*, Muhammad Sajid1, Abeera Sikandar2 and Faiza Rao3

OVERVIEW AND MECHANISMS OF ACTION

Attacking the Wall or Coating Surrounding Bacteria (Penicillin, the Wall Breaker)

Interfering with Bacteria Reproduction (Erythromycin, the Translation Blocker)

Blocking Protein Production in Bacteria (Tetracycline, the Protein Sniper)

Antibiotics and Pregnancy: Potential Risks

FDA Pregnancy Categories

Safety of Antibiotics by Category

Antibiotics considered Safe during Pregnancy

Antibiotics that may Pose Risks

Antibiotic use and Fetal Health

Impact on Maternal and Infant Microbiota

Risks of specific Antibiotics

Antibiotic Resistance and Preterm Premature Rupture

Macrolide use and Birth Outcomes

Macrolide Association with Miscarriages

Impact on Gut Microbiota

Developmental Risks from Antibiotic Exposure

Effects of Timing and Type of Antibiotics

Indication and Consideration during Pregnancy

COMMUNICATION BETWEEN HEALTHCARE PROVIDERS AND PREGNANT PATIENTS

ALTERNATIVE APPROACHES AND PREVENTIVE MEASURES

Antibiotic Resistant Infections

Syeda Sadaf Akber1,*, Faiza Rao2, Farwa Sidique3, Hammad Ali Hassan4 and Anam Rao5

Understanding Antibiotic Resistance

Scope of the Problem

THE HISTORY OF ANTIBIOTICS

Discovery

Emergence of Resistance.

Mechanisms of Antibiotic Resistance

Genetic Mutations

Genetic Exchange and Antimicrobial Resistance

Biofilm Formation

MAJOR ANTIBIOTIC-RESISTANT PATHOGENS

Methicillin-Resistant Staphylococcus aureus (MRSA)

Extended-Spectrum Beta-Lactamase (ESBL)-Producing Bacteria

FACTORS CONTRIBUTING TO THE RISE OF ESBLS

STRATEGIES TO ADDRESS ESBL-PRODUCING BACTERIA

CARBAPENEM-RESISTANT ENTEROBACTERIACEAE (CRE)

VANCOMYCIN-RESISTANT ENTEROCOCCI (VRE) :

FACTORS CONTRIBUTING TO ANTIBIOTIC RESISTANCE

Overuse and Misuse of Antibiotics

NEED FOR MODERN ANTI-MICROBIAL IMPROVEMENT

IMPACT OF ANTI-MICROBIAL RESISTANCE ON MORTALITY AND MORBIDITY

STRATEGIES TO COMBAT AMR

DELAYED HEALING CENTER REMAINS

FINANCIAL BURDEN

ELECTIVE APPROACHES TO ANTI-MICROBIALS

Phage Treatment

ANTI-MICROBIAL COMBINATIONS

IMMUNOTHERAPY

KEY ASPECTS OF IMMUNOTHERAPY IN ALTERNATIVE ANTIMICROBIALS

ANTI-MICROBIAL RESISTANCE AND ONE HEALTH

The Interconnecting of Human, Animal, and Environmental Health

Components and their Interconnections

Key Interconnections

STRATEGIES FOR COLLABORATIVE ACTION

ONE HEALTH EDUCATION AND AWARENESS

FUTURE PROSPECTS AND CHALLENGES

Advances in Genomic Sequencing and Surveillance

THE ROLE OF ARTIFICIAL INTELLIGENCE AND MACHINE LEARNING

ETHICAL CONSIDERATIONS

CONTROLLING THE SPREAD OF MRSA IN HEALTHCARE SETTINGS

Contamination Avoidance and Control

Screening and Reconnaissance

Anti-microbial Stewardship

Instruction and Preparing

Cohorting and Confinement

Observation of Healthcare Specialists

Collaboration and Communication

Natural Contemplations

HANDLING MULTI-DRUG SAFE TUBERCULOSIS (MDR-TB)

Fortifying TB Control Programs

Drug-Resistant TB Treatment

Bolster

Disease Avoidance and Control

Collaboration and Associations.

Investigation and Advancements.

Notes:

Description based on publisher supplied metadata and other sources.

Other Format:

Print version: Rao, Faiza Antibiotics and Reproductive Health

ISBN:

9789815313628

OCLC:

1528358815