Natural Products for Treatment of Skin and Soft Tissue Disorders / edited by Heba A. S. El Nashar, Mohamed El Shazly, and Nouran M. Fahmy.

Format:

Book

Author/Creator:

Nashar, Heba A.S. El, Author.

Contributor:

Nashar, Heba A. S. El, editor.

Shazly, Mohamed El, editor.

Fahmy, Nouran M., editor.

Language:

English

Subjects (All):

Dermatology.

Pharmacognosy.

Physical Description:

1 online resource (264 pages)

Edition:

First edition.

Place of Publication:

Singapore : Bentham Science Publishers Pte. Ltd., 2023.

Summary:

Natural Products for Treatment of Skin and Soft Tissue Disorders presents a simple and straightforward exploration of the role medicinal plants play in treating a diverse range of skin-related disorders. With contributions from researchers worldwide, this book delves into the pathology of skin conditions such as eczema, superficial mycoses, acne, vitiligo, and skin ulcers, providing effective treatment protocols using natural remedies. It also addresses prevalent disorders like atopic dermatitis and skin infections in developing countries. Finally, the book sheds light on the rising concern of skin cancer and potential natural therapeutic approaches. Readers will be equipped with the knowledge to harness the power of natural medicines in their dermatology practice.This comprehensive resource serves as a handbook for medical residents, students and dermatologists, offering invaluable insights into the potential of medicinal plants for the treatment of skin and soft tissue disorders.

Contents:

Cover

Title

Copyright

End User License Agreement

Contents

Foreword

Preface

ACKNOWLEDGEMENTS

Dedication

List of Contributors

Eczema, Etiology and Treatment

Humaira Bilal1, Mehnaz Showkat1 and Nahida Tabassum2,*

INTRODUCTION

Diagnosis

Atopy Patch Test (APT)

Skin Prick Tests (SPT)

Severity Scoring of Atopic Dermatitis (SCORAD)

TYPES OF ECZEMA

Severity Classification of Atopic Dermatitis

ETIOLOGY

Genetics

Skin Barrier Defects

Microbial Colonization and Superinfection

Immunological Dysfunction or Regulation

Altered Lipid Composition

Neuroinflammation

Food Allergies and Other Environmental Factors

TREATMENT

CONVENTIONAL TREATMENT

Topical Therapy

Emollients

Natural Emollients

Topical Corticosteroids (TCs)

Topical Calcineurin Inhibitors (TCIs)

Phosphodiesterase-4 (PDE4) Inhibitors

Topical Antibiotics

Phototherapy

Broad Band UV-B/ BBUVB (290-320nm)

Narrow-Band UVB/ NBUVB (311-313nm)

UVA-1 (340-400nm)

Combined UVA/UVB (280+400nm)

Psoralens+ UVA therapy (PUVA)

Excimer Lasers for Targeted Areas (el) (308nm)

Blue Light (400-495nm)

Common Side- Effects of Phototherapy

Uncommon Effects on Prolonged Therapy

Systemic Therapy

Immunosuppressive Therapy

Oral Corticosteroids (OCs)

Cyclosporine (Cys A)

Azathioprine

Methotrexate (MTX)

Mycophenolate Mofetil (MMF)

Immunomodulatory Therapy

Alitretinoin

Biologics

Dupilumab

Ustekinumab

Apremilast

Immunoglobulins

Interferons

Oral Antimicrobials

Complementary and Alternative Therapies

Prebiotics and Probiotics

Vitamin D

Allergen-Specific Immune Therapy (ASIT)

Psychosomatic Counselling

NOVEL THERAPEUTIC TREATMENT

Monoclonal Antibodies

JAK Receptor Inhibitors

H4R Antagonists

Topical PDE4 Inhibitors.

AhR Modulating Agents

Topical TRPV1R Antagonists

Oral S1P Modulators

HERBAL TREATMENT

Traditional Herbs

Althea Officinalis (Common Name: Marshmallow

Family: Malvaceae)

Arnica Montana (Common Name: Wolf's Bane

Family: Asteraceae)

Avena Sativa (Common Name: Oat

Family: Poaceae)

Glycyrrhiza Glabra (Common Name: Liquorice

Family: Fabaceae)

Linum Usitatissimum (Common Name: Linseed

Family: Linaceae)

Matricaria Recutita (Common Name: German Chamomile, Family: Asteraceae)

Oenotherae Oleum (Common Name: Evening Primrose Oil

Family: Onagraceae)

Stellaria Media (Common Name: Chickweed

Family: Caryophyllaceae)

Viola Tricolor (Common Name: Wild Pansy

Family: Violaceae)

Chinese Medicine (CM)

Essential Oils

CONCLUSION

REFERENCES

Superficial Mycoses as a Challenging Skin Disorder

Wiwit Suttithumsatid1 and Pharkphoom Panichayupakaranant1,*

SUPERFICIAL MYCOSES AND PATHOPHYSIOLOGY

Pityriasis Versicolor

Dermatophytosis

Candidiasis

EPIDEMIOLOGY OF SUPERFICIAL MYCOSES

CURRENT TREATMENTS FOR SUPERFICIAL MYCOSES

TARGETING FOR NOVEL DRUG THERAPY AGAINST SUPERFICIAL MYCOSES

HERBAL PRODUCTS WITH ANTIFUNGAL EFFECTS

Allium Sativum

Aloe Vera

Alpinia Galanga

Annona Squamosa

Camellia Sinensis

Cinnamomum Cassia

Citrus Bergamia

Curcuma Longa

Cymbopogon Citratus

Impatiens Balsamina

Jasminum Sambac

Rhinacanthus Nasutus

Sapindus Emarginatus

Senna Alata

Zingiber Officinale

PATENTS OF HERBAL AND PHYTOCHEMICAL PRODUCTS AGAINST SUPERFICIAL MYCOSES

Acne and Current Possible Treatments

Yaseen Hussain1,* and Haroon Khan2

Conventional Therapies for Acne

Pharmacological Targets for Phytochemicals Targeting Acne.

CURRENT POSSIBLE TREATMENTS USING PHYTOCHEMICALS

Phytochemicals

Nano Phytochemicals

Vitiligo and Treatment Protocols

Mehnaz Showkat1, Humaira Bilal1, Bilquees Bhat1 and Nahida Tabassum2,*

TYPES

Conventional Treatment Protocols

Non Surgical Therapies

Phototherapy/Light Therapy

Psoralen Plus UVA (PUVA) Therapy

Adverse Effects and Contraindications

Narrow Band UVB (NBUVB) Therapy

Alternate Protocols

Broad Band UVB (BBUVB) Therapy

Khellin Plus UVA (KUVA) Therapy

Phenylalanine Plus UVA (Phe-UVA) Therapy

Corticosteroids

Topical Corticosteroids

Systemic Corticosteroids

Topical Calcineurin Inhibitors (TCIs)/Topical Immunomodulators (TIMs)

Flip Top Pigment Transplantation

Cellular Grafts

Non-Cultured Keratinocytes and Melanocytes Transplantation

Autologous Cultured Melanocyte Transplantation

Cultured Epidermal Grafts

Depigmentation Therapy

Bleaching Agents

Monobenzylether of Hydroquinone (MBEH)

Monomethyl Ether of Hydroquinone/4-0 Methoxyphenol (4-MP)

Phenol

Laser Therapy

Q-Switched Ruby (QSR) Laser (694nm)

Q-Switched Alexandrite (QSA) Laser (755nm)

NOVEL TREATMENT PROTOCOLS

Excimer Laser Therapy

Topical Vitamin D3 Analogues

Cryotherapy

Depigmenting Agents

Imatinib

Imiquimod

Diphencyprone (DPCP)

Intradermal Therapy/ Mesotherapy

Inhibition of IL-15 Signalling With Anti-CD122 Antibody

Janus Kinase (JAK) Inhibitors

Alpha-Melanocyte Stimulating Hormone Agonistic Analog-Afamelanotide

Combination of Climatotherapy and Pseudocatalase Cream (PC-KUS)

Antioxidants

Microneedling

Prostaglandins

HERBALS IN VITILIGO

Ammi Majus (Common Name: Bishop's Weed

Family: Apiaceae)

Azadirachta Indica (Common Name: Neem.

Family: Meliaceae)

Cassia Occidentalis (Common Name: Coffee Senna, Kasaunda

Family: Caesalpiniaceae)

Cucumis Melo (Common Name: Melon

Family: Cucurbitaceae)

Ginkgo Biloba (Common Name: Maiden Hair Tree

Family: Ginkgoacea)

Lespedeza Bicolor (Common Name: Shrubby Bushclover

Family: Leguminosae)

Malytea Scurfpea (Common Name: Buguzhi

Nigella Sativa (Common Name: Black Cumin

Family: Ranunculaceae)

Picrorhiza Kurroa (Common Name: Kutki

Family: Plantaginaceae)

Piper Nigrum (Common Name: Black Pepper

Family: Piperaceae)

Polypodium Leucotomos (Common Name: Calaguala

Family: Polypodiaceae)

Psoralea Corylifolia (Common Name: Babchi

Pyrostegia Venusta (Common Name: Flamevine

Family: Bignoniaceae)

Rhododendron Schlippenbachii (Common Name: Royal Azalea

Family: Ericaceae)

Salvia Miltiorrhiza (Common Name: Red Sage

Family: Lamiaceae)

Atopic Dermatitis Prevalence and How to Manage It

Epidemiology, Diagnosis, Prevention, Policy and Treatment Schemes of Skin Infections in Developing Countries

Skin Cancer as an Emerging Global Threat and Potential Natural Therapeutic

Nadia Mushtaq1, Aqsa Arooj2, Areeba Akhtar3 and Abdul Jabbar4,*

Variants of Skin Cancer

Risk Factors

A Lighter Natural Skin Color

Skin that Burns, Freckles, Reddens Easily, or Becomes Painful in the Sun

Older Age

Ultraviolet Radiation Exposure

The Incidence of Skin Cancer and Mortality Across the Globe

Incidence

Mortality

HDI (Human Development Index)

Health System Costs

Skin Cancer Prevention and Control Strategies

Primary Prevention of Skin Cancer (Avoiding the Development of Diseases).

Secondary Prevention of Skin Cancer (Early Detection and Treatment of Diseases)

Tertiary Prevention of Skin Cancer (Prevention of Progression and Complications)

Control Strategies

Treatment Through Natural Therapeutics-Nutraceuticals

Kaempferol-with Anti-Cancer Potential

Magnolol-Prevention and Treatment of Cancer

Honokiol-Potent at Oncogenic Targets

Black Salve-An Escharotic

Pomegranate-A Potent Natural Therapeutic

Euphorbiaceae

Curcumin

Hypericum Perforatum L. - A Photomedicine

Skin Ulcers as a Painful Disorder with Limited Therapeutic Protocols

Thongtham Suksawat1 and Pharkphoom Panichayupakaranant1,*

SKIN ULCERS AND PATHOPHYSIOLOGY

CURRENT TREATMENTS FOR SKIN ULCERS

Wound Cleansing

Wound Debridement

Wound Dressing

Infection Control

ALTERNATIVE THERAPEUTIC PROTOCOLS FOR ALLEVIATION OF SKIN ULCERS

HERBAL EXTRACTS AND PHYTOCHEMICALS AS MULTITARGET THERAPEUTIC AGENTS

Azadirachta Indica

Centella Asiatica

Embelia Ribes

Garcinia Mangostana

Lawsonia Inermis

Phoenix Dactylifera

Picrorhiza Kurroa

Piper Betle

Punica Granatum

Terminalia Spp.

COMMERCIALLY AVAILABLE PRODUCTS AND PATENTS

Subject Index

Back Cover.

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

Description based on print version record.

ISBN:

9789815124361

9815124366

OCLC:

1407313211