Punica granatum : cultivation, properties and health benefits / Rupesh K. Gautam, Smriti Parashar (editors).

Format:

Book

Contributor:

Gautam, Rupesh K., editor.

Parashar, Smriti, editor.

Series:

Botanical Research and Practices

Language:

English

Subjects (All):

Medicinal plants.

Pomegranate.

Physical Description:

1 online resource (378 pages)

Place of Publication:

Hauppauge, New York : Nova Science Publishers, [2021]

Summary:

"Pomegranate (Punica granatum L.) is an ancient fruit estimated to be introduced to human cultures around the world about 4000 years ago. It is native to Central Asia, from Iran and Turkmenistan to northern India regions, and is widely cultivated in Mediterranean, tropical and subtropical regions. The highest-quality pomegranate is grown in arid zones because it is tolerant to drought conditions. It is well known to humans for its nutritional, curative, and ornamental values. About 75% of individuals from developed countries use pomegranate in traditional medicine. Punica granatum: Cultivation, Properties and Health Benefits is an attempt to bring together important research work, literature, and scientific findings regarding Punica granatum L. This book aims to feature the medicinal importance of this plant and its journey from folk medicine to modern medicine. This book compiles various medical studies of pomegranate for treatment of cancer, Alzheimer's disease, diabetes, cardiovascular disorders, bacterial infections, ischemia, male infertility, arthritis, obesity, and skin diseases. It is reported to have antioxidant, antimicrobial, anti-diabetic, anti-cancer, and anti-inflammatory properties. The use of pomegranate as a natural source of medicine has steadily increased around the world in recent years"-- Provided by publisher.

Contents:

Intro

Contents

Preface

Introduction

History of Punica granatum

Chemical Constituents of Punica Granatum

Biological Activities of Punica Granatum

References

Chapter 1

Flower, Pollen, and Stigma Characteristics in Relation to Breeding in Pomegranate

Abstract

1. Introduction

2. Floral Biology in Pomegranate

3. Pollen Characteristics in Pomegranate

4. Stigma Characteristics in Pomegranate

5. Breeding in Pomegranate

Conclusion

Chapter 2

Pomegranate: A Source of Active Compounds with a Health-Promoting Role

Abbreviations

2. Phenolic Compounds as the Main Phytochemicals in Pomegranate

2.1. Phenolic Acids

2.1.1. Ellagic Acid

2.1.2. Hydrolyzable Tannins

2.1.3. Flavonoids

3. Health-Promoting Role of Pomegranate Polyphenols

4. Pomegranate Polyphenols Targeting Inflammation

4.1. Cardiovascular Protection by Pomegranate Polyphenols

4.2. Protection from Neurodegenerative Damage by Pomegranate Polyphenols

Chapter 3

Pharmacological Virtue of Punica granatum

2. Pharmacological Properties

2.1. Effect on Cardiovascular System

2.1.1. Atherosclerosis

2.1.2. Hypertension

2.1.3. Carotid Artery Stenosis

2.2. Chemoprotective Nature

2.2.1. Prostate Cancer

2.2.2. Breast Cancer

2.2.3. Lung Cancer

2.2.4. Skin Cancer

2.3. Antioxidant Properties

2.4. Use in Periodontal Diseases

2.5. Intervention in Other Diseases and Disorders

2.6. Metabolic Disorders

2.7. Menopausal Symptoms

2.8. Osteoporosis

2.9. Fungal, Bacterial &amp

Parasitic Infections

3. Quality Control and Standardization

Chapter 4

Punica granatum Polysaccharide Aided Nanoparticles: A Versatile Approach for Combating Cancer Complexities.

Abstract

2. Polysaccharides as a Therapeutic Excipient

3. Pomegranate Plant

4. Therapeutic Potentials of Pomegranate Extracts

4.1. Anticancer Properties of Pomegranate Extracts

4.2. Anticancer Properties of Pomegranate Polysaccharide

5. Cancer Nanomedicine

6. Pomegranate Based Nanoparticles in Cancer Management

Chapter 5

Punica granatum (Pomegranate): An Insight into the Prevention and Treatment of Cancer

2. Background on Pomegranate's Empire

2.1. Biological and Geographical Source

2.2. Morphology

2.3. Phytochemical Composition

2.4. Traditional and Modern Utility

3. Perspective of Pomegranate in Cancer Prevention and Treatment

3.1. Prostate Cancer

3.2. Breast Cancer

3.3. Colon Cancer

3.4. Lung Cancer

3.5. Skin Cancer

3.6. Blood Cancer

3.7. Liver Cancer

3.8. Pancreatic Cancer

3.9. Cervical Cancer

3.10. Brain Cancer

3.11. Bladder Cancer

Acknowledgments

Funding

Author's Contribution

Conflict of Interest

Chapter 6

Health Benefits of Punica granatum against Diabetes and Associated Complications

2. Diabetes Complications

3. Available Treatment

3.1. Treatment of Diabetes Mellitus

3.1.1. Drugs Used in Therapy

3.1.1.1. Insulin Types

3.1.1.2. Oral Hypoglycemic Agents

3.2. Herbal Treatments

4. Ethnobotany of a Herb: Punica granatum

4.1. Global Distribution

4.2. Botany

4.3. Mythological History

4.3.1. Pomegranate-One Fruit That Cures a Hundred Ailments

4.3.1.1. As a Tonic

4.3.1.2. Indigestion and Stomach Disorders

4.3.1.3. Cough and Cold

4.3.1.4. Nose Bleeding

4.3.1.5. Tooth Problems

4.3.1.6. Fever

4.3.1.7. Foul Breath

4.3.1.8. Heart Palpitation.

4.3.1.9. Intestine and Liver Problems

4.3.1.10. Miscarriage

4.3.1.11. Menstrual Problems

4.3.1.12. Leucorrhoea

4.3.1.13. Night Discharge

4.3.1.14. Polyuria

4.3.1.15. Lice

4.3.1.16. Jaundice

4.3.1.17. Beauty Treatment

4.4. Traditional Uses of P. Granatum

4.4.1. Heart Problems

4.4.2. Stomach Disorder

4.4.3. Dental Care

4.4.4. Cancer (Sally, 2018, Bhowmik, et al., 2013)

4.4.5. Osteoarthritis

4.4.6. Diabetes

4.4.7. Anemia

4.5. Health Benefits of P. granatum (Bhowmik, et al., 2013)

4.6. Chemical Constituents of P. granatum

4.6.1. Tannins

4.6.2. Flavonoids

4.6.3. Alkaloids

4.6.4. Triterpenes, Ursolic Acid and Oleanolic Acid

5. Therapeutical Benefits in Diabetes and Its Complications

5.1. Peel

5.2. Juice

5.3. Flower

5.4. Leaves

5.5. Seeds

5.6. Roots and Bark

6. Summary of Etiopathogenesis and Mechanisms of Phytoconstituents

Chapter 7

Role of Punica granatum on Endothelial Dysfunction in Myocardial Ischemia-Reperfusion Injury

2. Endothelial Dysfunction: Cause or Consequence of Myocardial I/R Injury

2.1. Role of Oxidative Stress in Myocardial I/R Injury

2.2. Role of Nitric Oxide in Myocardial I/R Injury

2.3. Other Pathological Events Contributing to Myocardial I/R Injury

3. Protective Role of Punica Granatum on Endothelial Dysfunction

3.1. Effect of Punica Granatum on Oxidative Stress

3.2. Effect of Punica granatum on Nitric Oxide Level

3.3. Effect of Punica granatum on Other Pathological Mechanism and Myocardium I/R Biomarkers

4. Effect of Other Potential Bioactive Herbs and Their Components on Endothelial Dysfunction

5. Future Aspects

Chapter 8

Cardioprotective Effects of Pomegranate for Healthy Heart

Introduction.

1. Phytoconstituents in Pomegranate

1.1 Tannins (Hydrolyzable)

1.2. Ellagitannins

1.3. Hydroxybenzoic Acid and Hydroxycinnamic Acid

1.4. Gallotannins

1.5. Alkaloids and Lignans

1.6. Flavonoids

1.7. Anthocyanins

2. Beneficial Effects of Pomegranate

2.1. Anti-Inflammatory Effects

2.2. Effects in Metabolic Disorders

2.3. Effects on Cardiovascular Disorders

2.4. Anti-Cancer Effects

2.5. Effect on Skin

3. Potential Benefits of Pomegranate Phytoconstituents against Cardiovascular Diseases

3.1. Pomegranate against Myocardial Ischemia/Reperfusion Injury

3.2. Pomegranate against Atherosclerosis

3.3. Pomegranate against Hypertension

3.4. Pomegranate against Hypertrophiccondition and Heart Failure

Future Scope

Chapter 9

Potential Benefits and Effects of Pomegranate in Metabolic Disorders

1. Active Phytoconstituents in Pomegranate

2. Effects of Pomegranate in Lipid Metabolic Diseases

2.1. Anti-Atherosclerotic Effect of Pomegranate

2.2. Anti-Diabetic Effect of Pomegranate

2.3. Effect of Pomegranate in NAFLD

2.4. Anti-Obesity Effect of Pomegranate

2.5. Anti-Hypertensive Effect of Pomegranate

3. Toxicity and Safety Profile

4. Future Perspective

Chapter 10

Therapeutic Potential of Punica granatum L. (Pomegranate)

in Neurological Diseases

1. Pomegranate

1.1. Pomegranate Phytoconstituents

1.1.1. Gallic Acid

1.1.2. Ellagic Acid

1.1.3. Flavonoids

1.1.4. Lignans

1.1.5. Triterpenoids and Phytosterols

1.1.6. Alkaloids

1.1.7. Indolamines

2. Neuroprotective Effects of Pomegranate

2.1. Antiepileptic Effects of Pomegranate

2.2. Anti Depressive Effects of Pomegranate

2.3. Anti-Anxiety Effects of Pomegranate.

2.4. Protective Effects of Pomegranate in Cerebral Ischemia

2.5. Protective Effects of Pomegranate in Neurodegenerative Diseases

Chapter 11

Therapeutic Benefits of Bioactive Components of Punica granatum in Neurodegenerative Disorders

2. Neurodegenerative Diseases

3. Neutraceuticals in Treatment of Neurodegenerative Diseases

4. Health Benefits of Pomegranate

4.1. Benefits of Pomegranate in Cognitive Impairment

4.2. Benefits of Pomegranate in Neuroinflammation

4.3. Benefits of Pomegranate in Neurodegeneration

4.4. Role of Pomegranate in Alzheimer's Disease (AD)

4.5. Role of Pomegranate in Parkinson's Disease (PD)

4.6. Role of Pomegranate in Multiple Sclerosis

Chapter 12

Clinical Applications and Herbal Formulations of Punica granatum L.

2. Clinical Applications of P. granatum

2.1. Cancer

2.1.1. Prostate Cancer

2.1.2. Bladder Cancer

2.1.3. Colon Cancer

2.1.4. Breast Cancer

2.1.5. Lung Cancer

2.1.6. Skin Cancer

2.2. Atherosclerosis

2.3. Metabolic Disorders

2.4. Hypertension

2.5. Carotid Artery Stenosis

2.6. Myocardial Perfusion

2.7. Infections

2.7.1. Bacterial and Fungal Infections

2.7.2. Virus Infection

2.7.3. Parasitic Infection

2.8. Central Nervous System Disorders

2.8.1. Cognitive Disorders

2.8.2. Ischaemic Stroke

2.8.3. Multiple Sclerosis

2.8.4. Neonatal Hypoxic-Ischemic Brain Injury

2.9. Skin Disorders

2.10. Male Infertility

2.11. Erectile Dysfunction

2.12. Dental Conditions

2.12.1. Dental Plaque

2.12.2. Periodontal Disease

2.12.3. Denture Stomatitis

2.13. Inflammation

2.13.1. Gastric Inflammation

2.13.2. Intestinal Inflammation

2.13.4. Joint Inflammation.

2.13.5. Respiratory Inflammation.

Notes:

Includes bibliographical references and index.

Description based on print version record.

Other Format:

Print version: Gautam, Rupesh K. Punica Granatum: Cultivation, Properties and Health Benefits

ISBN:

9781536198218

OCLC:

1257666702