Advanced glycation end-products : sources and effects / Patrik Bast, editor.

Format:

Book

Contributor:

Bast, Patrik, editor.

Series:

Biochemistry and molecular biology in the post genomic era.

Biochemistry and molecular biology in the post genomic era

Language:

English

Subjects (All):

Advanced glycation end products.

Glycosylation.

Maillard reaction.

Physical Description:

1 online resource (146 pages) : illustrations.

Place of Publication:

New York : Nova Science Publishers, Incorporated, [2020]

Summary:

"Advanced Glycation End-Products: Sources and Effects attempts to describe the role of advanced glycation end-products, particularly dietary advanced glycation end-products, in the pathological expansion of adipose tissue as well as their implications in the development of obesity associated complications. The effects of advanced glycation end-products on vasculature and their pathological implications are also described, focusing on the epigenetic mechanisms (particularly that of miRNA) modulating their effects. The authors summarize the information available on the impact of hyperglycemia on the influencing factors of non-enzymatic glycosylation, the formation of advanced glycation end-products, and the role of advanced glycation end-products and their specific receptors in diabetes. The role of advanced glycation end-products to diabetic complications is examined in conjunction with the protective role of the endogenous secretory receptor for advanced glycation end-products (esRAGE) and the therapeutic interventions that would mimic esRAGE activity. In closing, poly-L-lysine modified with advanced glycation end-products is prepared and used as an antigen to generate a single-chain fragment variable monoclonal antibody (scFv mAb) through phage display technology"-- Provided by publisher.

Contents:

Advanced glycation end-products and adipose tissue dysfunction / Manu Sudhakar

Advanced glycation end products and their effects on vascular cell function- modulation by miRNAs / S. Manju Devi and P.R. Sudhakaran

Glycation, advanced glycation end products and diabetes / Haixia Chen and Yue Chen

Role of endogenous secretory receptor for advanced glycation end product in diabetes mellitus and its complications / R. Vimalavathini and S.H.R. Subhashri

Protective role of salinity a gainst the accumulation of advanced glycation end products in embryogenic suspension cultures of dactylis glomerata L. / Eva Popova, Lyuben Zagorchev, Rositsa Tsekovska, Roumyana Mironova and Mariela Odjakova.

Notes:

Description based on print version record.

Includes bibliographical references and index.

ISBN:

1-5361-7555-2