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The biological basis of mental health / William T. Blows.
- Format:
- Book
- Author/Creator:
- Blows, William T., 1947- author.
- Language:
- English
- Subjects (All):
- Biological psychiatry.
- Mental illness--Physiological aspects.
- Mental illness.
- Psychiatric nursing.
- Physical Description:
- 1 online resource
- Edition:
- 4th ed.
- Place of Publication:
- London, England ; New York, New York : Routledge, [2022]
- Summary:
- 520 This book explores the underlying biology and neuroscience associated with mental health and wellbeing. This fully revised fourth edition includes new chapters on behavioural science, and brain-gut and brain-gender connections, as well as expanded content on memory and genetics. Integrating up-to-date pharmacological and genetic research with an understanding of environmental factors that impact on human biology, The Biological Basis of Mental Health covers topics including brain development, neural communication, neurotransmitters and receptors, hormones and behaviour, genetic disorders, pharmacology, substance misuse, anxiety, schizophrenia, depression, epilepsy, subcortical degenerative diseases of the brain, dementia, developmental disorders, and sleep. This unique textbook is an essential read for all healthcare students, practitioners and educators with an interest in mental health and neuroscience.
- Contents:
- Cover
- Half Title
- Title Page
- Copyright Page
- Table of Contents
- List of figures
- List of tables
- Preface
- Chapter 1 Introduction to the brain
- Introduction: The overall structure of the brain
- The cerebrum
- The limbic system
- The thalamus, hypothalamus and pituitary gland
- The basal ganglia, cerebellum and claustrum
- The brain stem
- The main connectivity pathways involved in mental health
- The meninges and cerebrospinal fluid
- The blood-brain barrier (BBB)
- The central, peripheral and autonomic nervous systems
- The basic principles of brain pathologies affecting mental health
- Mental health problems related to the COVID-19 pandemic (2019-2022)
- Brain biomarkers
- Key points
- Notes
- References
- Chapter 2 Brain development
- Introduction
- The nervous system up to birth
- The debate: When does consciousness start?
- The brain at birth
- Infant and child brain development
- The teenage brain
- Hormone influences on brain development
- Nutritional influences on brain development
- Note
- Chapter 3 Neural communication
- The neuron
- Neurotransmission
- Synapses
- Neuroglia
- Chapter 4 Neurotransmitters and receptors
- Introduction to neurotransmitters
- Receptors
- The amine neurotransmitters
- The amino acid neurotransmitters
- The peptide neurotransmitters
- Endogenous opioids
- Other neurotransmitters
- Chapter 5 The brain-body connections: Gut microbiota, immunity and brain gender
- The gut microbiota and immunity
- Brain gender
- Chapter 6 Hormones
- Introduction: Hormones, form and function
- The pituitary gland and hormones
- The thyroid hormones
- Hormones from the adrenal cortex
- Hormones from the adrenal medulla
- Sex hormones.
- Key points
- Chapter 7 Behaviour
- Aggression
- Antisocial, criminal and psychopathic behaviour
- Introverts and extroverts
- Creativity
- Exercise and the brain
- Behavioural disorders
- Eating disorders
- Chapter 8 Genetics I: Introduction and autosomes
- Chromosomes and genes
- Disorders of inheritance
- Autosomal genetic disorders
- Chromosomes
- Chapter 9 Genetics II: Sex chromosomes and gene disorders
- The sex chromosomes: X and Y
- Immediate early genes (IEGs) and late response genes
- Epigenome and genomic imprinting disorders
- Chapter 10 Pharmacology
- Pharmacokinetics
- Pharmacodynamics
- Pharmacotherapeutics
- Pharmacogenetics and pharmacomicrobiomics
- Chapter 11 Illicit substance use disorders
- Introduction and the brain reward pathway
- The opiate drugs
- Cocaine
- Amphetamines and other dopamine-enhancing drugs
- Cannabis
- The hallucinogenic drugs
- Drugs of addiction used in medicine
- Chapter 12 Common substance misuse
- Alcohol
- Nicotine
- Caffeine
- Chapter 13 Emotions
- The amygdala
- Happiness
- Religious experiences
- Love
- Music
- The paranormal
- Emotional intelligence
- Chapter 14 Stress, anxiety and fear
- The biology of stress
- Physical effects of stress and General Adaptation Syndrome
- Stress and child abuse
- The biology of fear
- Anxiety disorders
- Anxiety-related personality disorders
- Genetics of anxiety disorders
- The anxiolytic drugs
- Chapter 15 Schizophrenia.
- Introduction
- The genetic influence in schizophrenia
- Brain pathology
- Neurodevelopment and the "big brain" theory
- The biochemical changes in schizophrenia
- The possible role of environmental factors
- Schizoaffective disorder and schizoid-related personality disorders
- Chapter 16 The antipsychotic drugs
- The first-generation antipsychotics
- The second-generation antipsychotics (atypical antipsychotics)
- Issues related to antipsychotic drugs
- Pharmacokinetics of the antipsychotics
- Chapter 17 Affective disorders
- Mood disorders
- Suicide
- Biochemistry
- Immunity
- Electroconvulsive therapy (ECT)
- Depression in young people
- Chapter 18 Antidepressant drugs
- Introduction: The antidepressant drugs
- Tricyclic and related antidepressants
- Selective serotonin re-uptake inhibitors (SSRI)
- Other antidepressants
- Monoamine oxidase inhibitors (MAOI)
- Pharmacokinetics of the antidepressants
- Antidepressant issues
- Mood-stabilising drugs
- Chapter 19 Epilepsy
- Types of seizures
- The electroencephalogram (EEG)
- Factors involved in the cause of epilepsy
- The pathophysiology of epilepsy
- Tonic-clonic (grand mal) seizures
- Temporal lobe (psychomotor) epilepsy and hippocampal sclerosis
- Jacksonian seizures
- Infantile spasms and febrile convulsions
- Childhood epilepsies
- The anticonvulsant drugs
- The pharmacokinetics of the antiepileptic drugs
- The side-effects of the anticonvulsant drugs
- Anticonvulsant drug interactions and withdrawal
- Chapter 20 Subcortical degenerative disorders of the brain
- Introduction: The basal ganglia
- Parkinson disease (PD).
- The anti-Parkinson drugs
- Other drugs
- Other treatments
- Huntington disease (HD)
- Genetics
- Treatment of Huntington disease
- Wilson disease and Harvey disease
- History: The strange case of Harvey disease
- Chapter 21 Memory and learning
- The hippocampus
- Memory I: Introduction
- Memory II: The biology
- Memory III: Memory loss
- Mild cognitive impairment (MCI)
- Functional cognitive disorder (FCD)
- Future drug treatment for memory loss
- Learning
- Learning disorders
- Chapter 22 The ageing brain and dementia
- The natural ageing brain
- The dementias
- Alzheimer disease (AD)
- The neuropathology of Alzheimer disease
- Dementia with cortical Lewy bodies (DCLB)
- Vascular dementia
- Frontotemporal dementia (FTD) (Pick disease)
- Limbic-predominant age-related TDP-43 encephalopathy (LATE)
- Drugs used in dementia
- Chapter 23 Communication and developmental disorders
- Communication disorders
- Developmental disorders
- Intellectual disability
- Chapter 24 Sleep
- Why we sleep
- The physiology of the waking state
- Physiology of sleep
- Dreams
- Effects of sleep loss on health
- Sleep disorders
- Sleep medication
- Genetics index: Genes, chromosomes, genetic terms and syndromes
- Index.
- Notes:
- Includes bibliographical references and index.
- Description based on print version record.
- Other Format:
- Print version: Blows, William T., 1947- Biological basis of nursing. Biological basis of mental health.
- ISBN:
- 1-000-46269-2
- 1-003-09727-8
- 9781003097273
- OCLC:
- 1283857534
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