A closer look at kinase inhibition / Alex Tompson, editor.

Format:

Book

Contributor:

Tompson, Alex, editor.

Series:

Chemistry research and applications series.

Chemistry research and applications

Language:

English

Subjects (All):

Protein kinases--Inhibitors.

Protein kinases.

Physical Description:

1 online resource (214 pages).

Place of Publication:

New York : Nova Science Publishers, [2020]

Summary:

"A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases, the progress in their use, and the repurposing of approved kinase inhibitors as broad-spectrum antivirals. The key kinases, namely CLK1, DYRK1A, CDK5, GSK3 and CK1, are analyzed as data indicate that targeting these proteins may have therapeutic promise against Alzheimer's disease"-- Provided by publisher.

Contents:

Targeted therapy of tyrosine kinase inhibitor drugs for two different cancers (colon-rectal cancer and chronic myelogenous leukemia) and their resistance mechanisms / Gabriella Marfe, Stefania Perna and Carla Di Stefano

Role of kinases in antiviral therapeutics / Vaishali M. Patil and Neeraj Masand

In search of novel tau kinase inhibitors and their role in Alzheimer's therapy / Arvind Kumar Jain, Saloni Malla, C. Karthikeyan, Amit K.Tiwari, Piyush Trivedid and Anita Dutt Konara.

Notes:

Description based on print version record.

ISBN:

1-5361-6974-9