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Biotechnology : the science, the products, the government, the business / Ronald P. Evens.

Ebook Central Academic Complete Available online

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Format:
Book
Author/Creator:
Evens, Ronald P., author.
Series:
Drugs and the pharmaceutical sciences.
Drugs and the pharmaceutical sciences
Language:
English
Subjects (All):
Pharmaceutical biotechnology.
Pharmaceutical biotechnology industry.
Physical Description:
1 online resource (203 pages).
Edition:
First edition.
Place of Publication:
Boca Raton, FL : CRC Press, 2020.
Summary:
The over-riding premise for biotechnology in this book is bringing novel products to market to substantially advance patient care and disease mitigation. Biotechnology, over its relatively brief existence of 40 years, has experienced a mercurial growth. The vast educational need for biotechnology information in this rapidly burgeoning field is a basic rationale here. However a more prominent underpinning is that, bringing biotech products to market for patient care involves success in the following four areas of engagement simultaneously - scientific advances for healthcare technologies, novel and varied products for untreated diseases, regulatory authorities, and biotech companies. Features Comprehensive coverage of biotechnology science topics used in development and manufacturing Addresses all the scientific technologies within biotechnology responsible for products on the market and the pipeline Presents business issues such as marketing and sales of the products, as well as companies engaged, and how biotech business has evolved
Contents:
Cover
Half Title
Series Page
Title Page
Copyright Page
Table of Contents
Preface
Author
List of abbreviations
Chapter 1: Introduction
History of biotechnology
Description of biotechnology
Sciences of biotechnology
Current biotechnology product status
Chapter 2: Science of biotechnology - Recombinant DNA technology
Chapter 3: Science of biotechnology - Monoclonal antibody technology
Chapter 4: The science of biotechnology: Peptides, vaccines, cell and tissue therapy, liposomes, nanobiotechnology, animal-sourced products
Peptides
Vaccines
Tissue therapy
Liposomes
Nanobiotechnology
Animal and marine products
High-throughput screening
Combinatorial chemistry
Proteomics
Cell receptors, signal transduction and protein kinases
Cell therapy
Cell therapy and immuno-oncology
Chapter 5: The science of biotechnology: Molecular engineering (proteins, monoclonal antibodies, biosimilars)
Molecular engineering of proteins and peptides
Glycosylation
Pegylation
Monoclonal antibody engineering
Humanization of monoclonal antibodies and conjugates
Molecular fusion
Biosimilars
Biological product delivery and formulations
Chapter 6: The science of biotechnology: Oligonucleotides and genetics
Polymerase chain reaction
Oligonucleotide (RNA) therapeutics
Gene therapy
Pharmacogenomics
Biomarkers
Transgenic animals
Genomics
Gene editing
Chapter 7: Laws and regulations governing biological product approval and usage
Chapter 8: Biotechnology products and indications I. Proteins
Proteins - hormones
Proteins - enzymes
Proteins - growth factors
Proteins - interferons and interleukins (cytokines)
Proteins - blood coagulation factors
Proteins - toxins
Fusion protein products
Monoclonal antibodies.
Chapter 9: Biotechnology products and indications II
Vaccine products
Oligonucleotides
Tissue and cell engineering products
Polymers and other biotech products
Biological products (blood derivatives, tissue extracts, vaccines)
Chapter 10: Biotechnology industry
Biotech companies
Challenges of a biopharma company
Culture of a biotech company
Financing a biotech company
A biopharma company structure
Product research and development in biopharma industry
BioPharma success factors - additional areas
Overall measures of biotech success - product approvals, company acceptance, and sales performance
Biotechnology products and utilization
Summary
Bibliography
Index.
Notes:
Includes bibliographical references and index.
Description based on print version record.
ISBN:
0-429-67867-3
0-429-39929-4
9780429399299
OCLC:
1157922507

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