Properties and applications of alginate / Michael Y. Wilkerson, editor.

Format:

Book

Contributor:

Wilkerson, Michael Y., editor.

Series:

Life Sciences Research and Development

Language:

English

Subjects (All):

Alginates.

Alginates--Therapeutic use.

Alginates--Industrial applications.

Physical Description:

1 online resource (194 pages)

Edition:

First edition.

Place of Publication:

New York : Nova Science Publishers, Inc., [2022]

Summary:

"This book includes seven chapters, each focusing on modern research into properties and applications of alginate. The first chapter elucidates the reader to the structural properties and applications of alginate, and additionally discusses future development targets in various fields. The second chapter gives an overview into fabrication of ALG- and S-ALG-based submicron- and nano-sized gel particles with a focus on protein encapsulation. The third chapter returns to analyzing the unique physical properties of alginate and its current and potential uses. The fourth chapter reviews the development of alginate hydrogel beads by the process of microencapsulation, enabling the preservation of the entrapped material. The fifth chapter reviews new uses of alginate in the probiotic food industry as a carrier for probiotic immobilization, and summarizes the extrusion and spray dry techniques used to implement them. The sixth chapter gives a brief knowledge of the structure-property relationships, film formation, biocompatibility, and toxicity study of alginate and its different biomedical applications. The seventh and final chapter, after reviewing how alginate is discovered, describes the main properties of alginate, discusses the sources and chemical structure of alginate, and its various applications, especially in drug release and tissue engineering"-- Provided by publisher.

Contents:

Intro

Contents

Preface

Chapter 1

Alginate Properties and Applications

Abstract

Introduction

1. Chemical Structure

2. Sources of Alginates

2.1. Algal Alginates

2.2. Bacterial Alginates

3. Properties of Alginate

3.1. Molecular Weight

3.2. Solubility

3.3. Viscosity

3.4. Stability and Degradation

3.5. Selective Ion Binding

3.6. Gel Formation Ability

3.7. Biocompatibility

4. Modification of Alginates

4.1. Modification of Carboxyl Group

4.1.1. Esterification of Carboxyl Group

4.1.2. Carbodiimide Coupling

4.1.3. Covalent Cross-Linking

4.2. Chemical Modification of Hydroxyl Group

4.2.1. Esterification of Hydroxyl Groups

4.2.2. Oxidation

4.2.3. Sulfation

4.2.4. Graft Copolymerization

4.2.5. Phosphorylation

5. Types and Applications of Alginates

5.1. Alginates in Biomedical Applications

5.1.1. Alginates Microcapsules for Drug Delivery

5.1.2. Alginates Application in Tissue Engineering

5.1.3. Alginates Utilication in 3D Cell Culture Models

5.1.4. Alginate Application for Heart and Cardiovascular Disease

5.1.5. Alginates in Wound Dressings

5.1.6. Alginates in Metabolic Syndrome

5.1.7. Alginates Oligomers as Active Pharmaceutical Drugs

5.2. Alginate as a Functional Food Ingredient

5.2.1. Gelling, Thickening, Stabilising and Emulsifying Agent

5.2.2. Encapsulation and Immobilisation

5.2.3. Food Coating

5.3. Alginate Application in Industrial and Environmental Sciences

5.3.1. Water Treatment of Heavy Metal Ions

5.3.2. Textile Industries

5.3.3. Paper Making Industries

5.3.4. Tanneries

5.3.5. Release Agents

5.4. Agricultural Applications

Future Direction for Research

References

Biographical Sketch

Chapter 2.

Submicron and Nano-Sized Gel Particles Based on Alginate and Sulfated Alginate for Protein Encapsulation

Method

Materials

Synthesis of S-ALG

Synthesis of Biotinylated ALG and S-ALG

Evaluation of the Interaction between the Biotinylated Polymers and Lf

Fabrication of Gel Particles

Nanoprecipitation

Nanoprecipitation and Sonication

Lactoferrin (Lf) Stability

Characterisation

Statistical Analysis

Results and Discussion

Evaluation of the Binding Affinity of ALG and S-ALG to Lf

Synthesis and Characterisation of Gel Particles

First Series: Nanoprecipitation

Second Series: Nanoprecipitation and Sonication

Evaluation of Particle Isolation Process on Suspension Stability

Sonication Stability of Lf

Conclusion

Acknowledgments

Biographical Sketches

Chapter 3

An Insight into Properties and Applications of Alginate

Properties of Alginate

Derivatives of Alginate

Bioadhesion

Biocompatibility

pH Effect

Gelling Properties

Immunogenicity

Molecular Weight

Sterilization

Solubility

Toxicity

Applications of Alginate

Pharmaceutical Application

Application in Protein Delivery

Alginate in Cosmetics

Application as Wound Dressings

Application as Animal Feeds

Application in Textile Industry

Application in Welding Rods

Application in Food Industry

Conclusion and Future Perspective

Conflict of Interest

Chapter 4

Alginate Hydrogel Beads as Building Blocks for Delivering Polyphenols

Alginate - Physicochemical Properties and Sources

Gelation Properties

Alginate Sources

Alginate Characteristics

Application of Vibrating Technology to Produce Alginate Beads.

Microencapsulation of Polyphenols into Alginate Particles

Future Perspectives

Chapter 5

Alginate as a Carrier for Probiotic Immobilization: Extrusion and Spray Dry Technique

Alginate as Carrier

Encapsulation by Extrusion

The Extrusion Technique for Probiotic Immobilization

The Spray Dry Technique for Probiotic Immobilization

Acknowledgment

Chapter 6

Structure-Property Relationship of Alginate Polymers and Its Biomedical Applications

1. Introduction

2. Synthesis of Alginates

3. Applications of Alginates

3.1. Textile Printing

3.2. Food

3.3. Pharmaceutical and Medical Uses

3.3.1. Pharmaceutical Applications

3.3.2. Delivery of Small Chemical Drugs

3.3.3. Protein Delivery

3.3.4. In Pharmaceutical Industries

3.3.4.1. Wound Dressing

3.3.4.2. Cell Culture

3.3.4.3. Tissue Engineering

Chapter 7

Properties and Medical Applications of Alginate

Alginate Discovery

General Properties of Alginate

Structure and Characterization

Molecular Weight and Solubility

Hydrogel Formation

Medical Applications

Drug Release System

Tissue Engineering

Cartilage and Bone Tissue Engineering

Cardiac Applications

Wound Dressing

Film

Foam Dressing

Hydrogel Dressing

Cell Therapy

Conclusion and Perspectives

Index

Blank Page.

Notes:

Includes bibliographical references and index.

Description based on publisher supplied metadata and other sources.

Description based on print version record.

Other Format:

Print version: Wilkerson, Michael Y. Properties and Applications of Alginate

ISBN:

9798886973815

OCLC:

1348481207