The placenta and neurodisability / edited by Ian Crocker, Maternal and Fetal Health Research Centre, Institute of Human Development, University of Manchester, UK, and Martin Bax, emeritus reader in child health, Imperial College London, UK.

Format:

Book

Contributor:

Crocker, Ian, editor.

Bax, Martin, editor.

Series:

Clinics in developmental medicine (Unnumbered)

Clinics in developmental medicine

Language:

English

Subjects (All):

Placenta--Diseases.

Placenta.

Brain--Growth.

Brain.

Nervous system--Diseases--Etiology.

Nervous system.

Fetal growth disorders.

Fetal brain.

Physical Description:

1 online resource (169 p.)

Edition:

2nd ed.

Place of Publication:

London : Mac Keith Press, 2015.

Summary:

Many neurodevelopmental deficits originate in the perinatal period and there is increasing awareness of the need to look to early life, including prenatal life, to understand the origins of cognitive development and risk of neurodegenerative and psychiatric diseases.This comprehensive and authoritative book is structured in a logical way from pathology to clinical outcome. Throughout, information from the basic sciences is placed within the clinical context, and there is excellent use of illustrative figures and images. Written by leading obstetricians, neonatologists, paediatricians and pathologists, this volume collates the ever-increasing evidence, both pathological and epidemiological, for the critical role of the utero-placenta in neurodisability, both at term and preterm. It encapsulates new advances in antepartum and perinatal imaging, new clinical aspects of fetal compromise, recent evidence of endocrine, haematological and inflammatory origins of utero-placental dysfunction, and possible cerebro-protective interventions. This text is essential reading for everyone concerned with child development and the in utero origins of neurological disability.

Contents:

Contents ; Authors' Appointments ; Foreword ; Preface ; 1 Placental Pathology in Understanding Perinatal Brain Injury ; 2 Abnormal Placental Phenotypes ; 3 Aberrant Placental Endocrinology, Fetal Growth and Neurodevelopment ; 4 The Rheology of Utero-placental and Feto-placental Blood Flow ; 5 Inflammation and Placentation ; 6 Infections and the Fetal Inflammatory Response

7 Cerebral Ischaemia and White Matter Injury 8 In Utero Imaging of the Human Placenta ; 9 Cerebral Function and Fetal Growth Restriction ; 10 Placental Programming and Mental Illness: Fetal Growth and Schizophrenia ; 11 Cerebro-Therapeutics ; 12 Summing-Up and Unsolved Problems ; Index ; Color Plate Section

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

Description based on online resource; title from PDF title page (ebrary, viewed March 15, 2016).

ISBN:

9781909962552

1909962554

9781909962545

1909962546