Silk fibroin : advances in applications and research / edited by Shivaji H. Pawar.

Format:

Book

Contributor:

Pawar, S. H. (Shivaji Hariba), 1946- editor.

Series:

Recent trends in biotechnology.

Recent Trends in Biotechnology Series

Language:

English

Subjects (All):

Biomedical materials.

Silk.

Textile fibers.

Sericulture.

Nanobiotechnology.

Physical Description:

1 online resource (346 pages)

Edition:

First edition.

Place of Publication:

New York : Nova Science Publishers, Inc., [2023]

Summary:

"The book entitled "Silk Fibroin: Advances in Applications and Research" is an extensive collection of learned materials and new results focusing on advances in silk fibroin for their applications by the contributing authors who are experts working in the fields of nanoscience, material science, energy, agricultural, computer science and engineering, atmospheric nanoscience, medicine, and nanobiotechnology"-- Provided by publisher.

Contents:

Intro

Contents

Preface

Acknowledgments

Chapter 1

Introduction to Resources, Physico-Chemical Properties and Blends of Silk Fibroin

Abstract

1. Introduction

2. Resources of Silk Fibroin

2.1. History of Silk Fibroin

2.2. Silk Fibroin Sources

2.3. The Life Cycle of Silkworms

2.4. Silk Producing Insects

2.5. Production of Silk

2.6. Traditional Uses of Silk

2.7. Origins of Silk

2.7.1. Indian Silk

2.7.2. China Silk

2.8. Diseases of Silkworms

2.8.1. Pebrine (Protozoan Disease)

2.8.1.1. Causative Agents

2.8.2. Flacherie (Bacterial Disease)

2.8.2.1. Causative Agents

2.8.3. Grasserie (Viral Disease)

2.8.4. Muscardine and Aspergillosis (Fungal Disease)

2.8.5. Aspergillosis

3. Physical Properties of Silk

3.1. Structural Properties

3.1.1. Primary Structure of Silk Fibroin

3.1.2. Secondary Structure

3.2. Mechanical Properties

3.2.1. Structure-Dependent Mechanical Properties of Silk

3.3. Chemical Properties

3.3.1. Inorganic Acids/Alkalis

3.3.2. Concentrated Inorganic Alkalis/Acid

3.3.3. Dilute Alkali-Containing Protease

3.3.4. HCl with Neutral Salt System

3.3.5. NaOH with Strong Urea Solution

3.3.6. Organic Acid Complex System

3.3.7. Other One Components Organic Solvents

3.3.8. Ionic Liquids

3.3.9. Metal Complex System

3.4. Thermal Properties: Stability

3.5. Optical Properties

4. Blends of Silk Fibroin and Their Applications

4.1. Physical Forms of Blends for Their Applications

4.2. Blends of Silk Fibroin

4.2.1. Two-Component Blends

4.2.2. Other Polymer Blends

4.2.3. Three Component Blends

4.2.4. Inorganic Additives

4.2.5. Cross Linking

Conclusion

References

Chapter 2

Non-Mulberry Silk Fibroin Blends: The Road Underexplored

1. Introduction.

2. Regenerated Non-Mulberry Silk Fibroin Blends

3. Techniques for Developing Non-Mulberry Silk Fibroin Blends

3.1. Non-Mulberry Silk Fibroin Blends by Casting

3.2. Silk Fibroin Blend Fibrous Scaffolds

3.3. Silk Fibroin Blends through Freeze Drying

4. Properties of Non-Mulberry Silk Fibroin Blends

4.1. Structural Properties

4.2. Thermal Properties

4.3. Mechanical Properties

4.4. Biodegradability

4.5. Applications of Non-Mulberry Silk Fibroin Blends

4.6. Tissue Engineering Applications

4.6.1. Bone Tissue Engineering

4.6.2. Peripheral Nerve Tissue Regeneration

4.7. Cartilage Repair

5. Wound Healing Applications

Conclusion and Future Prospects

Chapter 3

Production and Applications of Silk Fibroin Thin Films

2. Silk Fibroin Thin Films

2.1. Physical, Chemical, Biological and Mechanical Properties

3. Applications to Tissue Engineering

3.1. Wound Healing

3.2. Cornea

3.3. Electronic and Optical Devices

3.4. Controlled Drug Release

Conclusion and Future Perspectives

Chapter 4

Silk Fibroin Sponge as a Cryodevice Combined with Transporter and Scaffold Functions in Cellular Transplantation

2. Preparation of the SF Sponge

3. Characterization of the SF Sponge

4. SF Application to Cryopreservation

5. SF Application to Islet Transplantation

5.1. Cytokine Transporter

5.2. Scaffold

Chapter 5

Silk Fibroin-Based Nanocomposite for Futuristic Electronics

2. Biomaterials in Electronics Applications

3. Potential of Silk Fibroin in Electronic Applications

4. Role of Inorganic Nanofiller-Based Nanocomposites in Electronic Applications.

5. Structure-Property Relationship of Silk Fibroin-Based Bio-Nanocomposites

6. Opto-Electronic Properties of Silk Fibroin-Based Bio-Nanocomposites

Chapter 6

Silk Fibroin-Based Systems for Conversion and Storage of Energy

2. Overview of the Energy Crisis and the Need for Smart Textiles to Capture Energy

3. Silk Fibroin-Based Conversion of Energy

3.1. Mechanical Energy Conversions with SF

3.1.1. Triboelectric Generators with SF

3.1.2. Piezoelectric Generators with SF

3.1.3. Hybrid Piezoelectric-Enhanced Triboelectric Nanogenerator with SF

3.2. Thermoelectric Energy Conversion and Refrigerator

4. Storage of Energy

4.1. Introduction to the Storage of Energy

4.2. The Basics of How a Supercapacitor Stores Energy

4.3. Utilizing Silk-Based Products for Energy Storage

4.3.1. Carbonized Silk is Used in Batteries and Supercapacitors

4.3.2. Self-Assembly of Silk-Graphene for Energy Storage

Chapter 7

Silk Fibroin as a Functional Biomaterial for Tissue Engineering

2. Biocompatible and Biodegradation

3. Tissue Engineering

4. Regeneration of Cartilage Tissue

5. Engineering Ligament and Tendon Tissues

6. Bladder Tissue Engineering

7. Bone Tissue Engineering

8. Regeneration of Ear Drums

9. Regeneration of Skin and Wound Tissues

10. Regeneration of Neural Tissues

11. Regeneration of Hepatic Tisssues

12. Regeneration of Spinal Cord Tissue

13. Fluorescent Silk Fibroin

14. Applications

15. Silk Fibroin-Based Flexible Electronics

16. Fibroin Nanoparticles: A Promising Drug Delivery System

Chapter 8

Silk Fibroin - A Diagnostic Tool for Targeted Drug Delivery System

1.1. Sources of Silk Fibroin

1.2. Cocoon (Bombyx Mori) Silk

1.2.1. Nephila Clavipes

1.3. Structure and Properties of Silk Fibroin

1.4. Mechanical Properties

1.5. Biocompatibility

1.6. Biodegradability and Bioresorbability

2. Drug Delivery System

2.1. Properties of Ideal Targeted Drug Delivery [89]

2.2. Strategies of Drug Targeting

2.2.1. Passive Targeting

2.2.2. Inverse Targeting

2.2.3. Active Targeting

2.2.4. Ligand-Mediated Targeting

2.2.5. Dual Targeting

2.2.6. Double Targeting

2.2.7. Combination Targeting

2.3. Advantages and Disadvantages of Targeted Drug Delivery

2.3.1. Advantages

2.3.2. Disadvantages

2.4. Silk Fibroin-Based Targeted Drug Delivery

2.5. Controlled Release Drug Delivery System

2.5.1. Advantages and Disadvantages of Controlled or Sustained Release Drug Delivery [163]

2.5.1.1. Advantages

2.5.1.2. Disadvantages

2.5.2. Mechanisms Involved for Controlling Drug Release

2.5.3. Factors Responsible for Designing a Controlled Release Drug Delivery System

2.5.4. Major Factors Involved in Drug-Related Parameters Are [165]

2.5.5. Classification of Controlled Release Drug Delivery Systems

2.5.6. Evolution of the Controlled Release Dosage Forms

Chapter 9

Silk Fibroin Nanoparticles as a Promising Tool for Controlled Drug Delivery

1.1. Conventional Carrier vs. Nanocarrier

1.2. Parameter to Nanoparticle Drug Delivery System

1.3. pH Sensitive System

2. Polymeric Nanosystems for Drug Delivery

2.1. Silk-Based Materials

2.2. Structure and Physicochemical Properties of SF

2.2.1. Structure

2.3. Properties of Silk Fibroin

2.3.1. Mechanical Properties

2.3.2. Biocompatibility

2.3.3. Biodegradation

2.3.4. Solubility Properties of Silk Fibroin.

3. Synthesis Methods of Silk Fibroin Nanoparticles

3.1. Desolvation Method

3.2. Salting Out Method

3.3. Electrospraying Method

3.4. Silkworm Feeding Method

4. Recent Advances in Drug Delivery System

5. Polymers in Drug Delivery System

5.1. Polysaccharides

5.2. Chitosan

5.3. Sodium Alginate

5.4. Starch

5.5. Proteins

5.6. Albumin

6. Silk-Based Drug Delivery System

6.1. Drug Incorporation

6.2. Drug Release

6.3. Application of SF as a Drug Delivery System

Chapter 10

Silk Fibroin: Advancement in Wound Healing Technologies

2. Wound Healing Mechanism with Silk Fibroin As a Suitable Biomaterial

2.1. Homeostasis

2.2. Inflammatory Phase

2.2.1. Early Inflammatory Response

2.2.2. Late Inflammatory Phase

2.3. Proliferative Phase

2.4. Maturation and Remodeling

3. Different Forms of Silk Fibroin for Wound Healing

3.1. Silk Fibroin Solution

3.2. Hydrogels

3.3. Films

3.4. Sponges

Acknowledgements

Chapter 11

Regulation of Cytokines in Wound Healing by Silk Fibroin

2. Role of Cytokines in Wound Healing

2.1. Pro-Inflammatory Cytokines

2.1.1. Interleukin-6 (IL-6)

2.1.2. Interleukin-1 (IL-1)

2.1.3. TumorNecrosis Factor (TNF)

2.1.4. Interferons (IFNs)

2.2. Anti-Inflammatory Cytokines

2.2.1. Interleukin-10 (IL-10)

2.2.2. Interleukin-4 (IL-4)

2.2.3. Transforming Growth Factor (TGF-β)

3. The Cascade of StepsFollowed by Pro-Inflammatory and Anti-Inflammatory Cytokines for Wound Healing

4. Silk Fibroin: A Natural Polymer for Wound Healing

5. Regulation of Pro and Anti-Inflammatory Cytokines by Silk Fibroin

6. Regulation of Wound Healing by Silk Fibroin-Mediated NF-kβ Signaling.

7. Other Pathways Involved in Wound Healing by Silk Fibroin.

Notes:

Includes bibliographical references and index.

Description based on publisher supplied metadata and other sources.

Description based on print version record.

Other Format:

Print version: Pawar, Shivaji H. Silk Fibroin: Advances in Applications and Research

ISBN:

9798886975161

OCLC:

1369638244