Nature's Arsenal Against Cancer.

Format:

Book

Author/Creator:

Guarve, Kumar.

Series:

Cancer Etiology, Diagnosis and Treatments Series

Language:

English

Subjects (All):

Cancer--Alternative treatment.

Cancer.

Cancer--Prevention.

Phytochemicals--Therapeutic use.

Phytochemicals.

Holistic medicine.

Physical Description:

1 online resource (289 pages)

Edition:

1st ed.

Place of Publication:

New York : Nova Science Publishers, Incorporated, 2024.

Summary:

"This book is an illuminating publication that explores the cutting-edge research and potential of natural compounds in the fight against cancer. This book provides a comprehensive and accessible overview of the diverse range of nature-based compounds derived from plants, marine organisms, fungi, and other sources, which have shown promising anti-cancer properties. Cancer remains one of the most challenging health issues worldwide, and the search for innovative and effective treatments continues. This book delves into the historical use of natural compounds in traditional medicine, highlighting their evolution into modern cancer research. With a focus on molecular mechanisms, the book reveals how these natural compounds combat cancer cells, induce apoptosis, and inhibit tumor angiogenesis, among other critical processes. Bringing together the latest research and advancements, this publication showcases preclinical studies demonstrating the efficacy of natural compounds in cell and animal models. Furthermore, it presents insights from clinical trials investigating the safety and potential benefits of natural compounds in cancer patients, thus bridging the gap between lab findings and real-world applications. Readers of all backgrounds, from researchers to healthcare professionals, will appreciate the valuable content presented in this book. The book discusses the advantages of natural compounds over traditional cancer treatments and addresses challenges in their development, including standardization and regulatory aspects. One of the book's key strengths lies in its exploration of integrative approaches, where natural compounds are combined with existing cancer therapies, offering a potential avenue for enhanced treatment outcomes and reduced side effects. With its wide-ranging scope, this book aims to serve as an essential resource for the academic community, healthcare practitioners, and students in oncology-related disciplines. Whether you seek a deeper understanding of molecular intricacies or new approaches to incorporate into clinical practice, this publication offers valuable insights and inspiration. As we forge ahead in the battle against cancer, this book stands as a beacon of hope, highlighting the immense potential of nature's offerings in our pursuit of effective cancer treatments as well as preventive strategies against cancer"-- Provided by publisher.

Contents:

Intro

Contents

Preface

Chapter 1

Introduction to Nature's Arsenal: Harnessing Natural Compounds in Cancer Research

Abstract

Abbreviations

Introduction

Recent Research/Studies in Cancer

Conclusion

References

Chapter 2

Understanding Cancer: Biology, Causes and Current Treatment

Biology of Cancer

Molecular Basis of Cancer

Differentiation, Anaplasia, and Dysplasia

Differentiation

Anaplasia

Dysplasia

Essential Alterations for Malignant Transformation

Self-Sufficiency in Growth Signals

Insensitivity to Growth Inhibitory Signals

Evasion of Apoptosis

Defects in DNA Repair

Unrestricted Proliferative Capacity

Angiogenesis

Invasion and Metastasis

Self-Sufficiency in Growth Signals: The Role of Genes, Proto-Oncogenes, Oncogenes, and Oncoproteins

Proto-Oncogenes and Oncogenes

Oncoproteins

Role of Growth Factors

Insensitivity to Growth Inhibitory Signals in Carcinogenesis

Evasion of Apoptosis in Cancer Development

Defects in DNA Repair and Their Role in Tumorigenesis

Angiogenesis in Tumor Development and Progression

Invasion and Metastasis: Hallmarks of Malignant Tumors

Invasion into the Extracellular Matrix

Vascular Dissemination and Homing of Tumor Cells

Role of Reactive Oxygen Species (ROS)

Role of Inflammation

Role of Chronic Infection

Role of Immunity

Causes of Cancer: A Comprehensive Overview of Carcinogenic Agents

Physical Carcinogens: The Impact of Radiation on Cellular Neoplasia

Ultraviolet Radiations (UV Rays)

Ionizing Radiations

Chemical Carcinogens: Mechanisms of Carcinogenesis

Initiation Phase

Promotion Phase

Microbial Carcinogens: Their Role in Cancer Development

Viral Carcinogens

Bacterial Carcinogens

Fungal Carcinogens.

Current Treatment Modalities in Cancer Therapy

Conventional Therapies

Role of Surgery in Cancer Treatment

Role of Radiotherapy in Cancer Treatment

Role of Chemotherapy in Cancer Treatment

Advanced Cancer Therapies

Chapter 3

Indigenous Traditional Knowledge of Healing Cancer and Associated Remedies

Abbreviation

Natural Products in Cancer Treatment

Taxol and Camptothecin

Camptothecin

Arsenic Trioxide

Vinca Alkaloids

Vinblastine

Vincristine

Vindesine

Curcumin

Epigallocatechin Gallate (EGCG)

Berberine

Carotenoids and Their Role in Cancer Treatment

Chapter 4

Natural Compounds in Cancer Treatment and Prevention

Natural Compounds with Anti-Cancer Properties

Resveratrol

Paclitaxel

Quercetin

Lycopene

Artemisinin

Chapter 5

Unraveling the Mechanisms: How Natural Compounds Combat Cancer Cells

ECGC

Catharanthus Roseus

Withania Somnifera

Nigella Sativa

Capsicum Annuum

Chapter 6

Phytochemicals Against Cancer: Exploring Plant-Based Compounds

Different Stages of Chemoprevention

Initiation

Promotion

Clonal Expansion

Promoters

Progress

Cancerous Transformation

Invasion of Surrounding Tissues

Increased Variability

Anticancer Mechanism of Action for Phytochemicals

Antioxidant Activity via Scavenging Free Radicals

Effects Against Inflammation via Blockage of Inflammatory Pathways

DNA Restoration and Genome Stability via Improved DNA Repair

Cell Cycle Control via Cell Cycle Abruption.

Apoptosis Induction via Activation of the Apoptotic Pathway

Anti-Angiogenesis

Hormone Modulation

Activation of Immune System

Epigenetic Regulation

Role of Phytochemicals in Chemoprevention

Chapter 7

Marine Compounds as Anti-Cancer Agents

Marine Compounds in Cancer Treatment

Tubulin Binding Agents

Eribulin

Plocabulin

DNA Targeting Agents

Cytarabine

Trabectedin

Lurbinectedin

Mechanistic Insights

Apoptosis

Anti-Metastatic Activity

Antiangiogenic Effect

P53 Upregulation

Stimulation of Histone Hyperacylation

Marine Compounds as Anti-Cancer Agents for Lung Cancer

Edible Polysaccharide

Tuberatolide B

Fucoxanthin

Extract of Chlorella Sorokiniana

Gliotoxin

ECHC

Marine Compounds as Anti-Cancer Agents for Colo-Rectal Cancer

Alkaloids

Peptides

Gluatminase

Ohmyungsamycin A

Actinomycin V

Androsamide

Laxaphycin B4

Terpenes

Trichodermaloid A

Rhinomilisn E

Smenospongine

Ilimaquinoe (IQ)

Dactylospontriol

13-Acetoxysar Cocrassolide

Polysaccharides

Fucoidan

Laminaran

Chapter 8

Culinary Cures: Integrating Dietary Compounds into Cancer Management

Carcinogenesis and Dietary Factors

DNA Damage and Repair

Inflammation

Hormone Regulation

Microbiome

Individual Nutritional Elements and the Risk of Cancer

Fruits and Vegetables

Fiber

Red And Processed Meats

Dietary Fat

The Role of Food Preparation and Cooking Methods

Personalized Nutrition and Genetic Variability

Impact of Nutrition on Cancer Progression

Tumor Growth and Nutrition

Inflammation and Immune Response

Hormonal Influences

Maintaining Nutritional Status during Treatment.

Psychological and Social Aspects

Dietary Compounds and Cancer Prevention

Phytochemicals

Antioxidant Properties

Anti-Inflammatory Effects

Detoxification and DNA Repair

Inhibition of Angiogenesis and Metastasis

Immune System Enhancement

Dietary Compounds and Cancer Treatment

Chemopreventive Potential of Dietary Polyphenols

Antioxidant Activity

Apoptosis Induction

Cell Cycle Regulation

Angiogenesis Inhibition

Anti-Metastatic Effects

Modulation of Signaling Pathways

Omega-3 Fatty Acids and their Impact on Cancer Treatment

Anti-Inflammatory Properties

Supportive Effects on Immune Function

Immunomodulatory Effects of Dietary Compounds in Cancer Therapy

Enhancement of Immune Cell Activity

Regulation of Cytokines

Support for Gut Microbiota

Nutrigenomics and Cancer

Genetic Variability

Inflammation and Immunity

Metabolism and Energy Balance

Integrating Culinary Approaches in Cancer Management

Nutritional Guidance for Individuals with Cancer

Designing Anti-Cancer Meal Plans

Culinary Techniques to Preserve Nutrient Value

Steaming

Microwaving

Blanching

Raw or lightly cooked

Grilling and roasting

Using the Right Cooking Oil

Canning and Freezing

Avoid Overcooking

Specific Dietary Compounds and Their Anti-Cancer Effects

Garlic: A Potential Anti-Cancer Dietary Compound

Green Tea's Catechins and Their Role in Preventing Cancer

Cruciferous Vegetables and Sulforaphane: An Anti-Cancer Arsenal

Case Studies and Clinical Evidence

Case Studies Demonstrating Dietary Compounds' Impact on Cancer Management

Case 1. Curcumin as an Adjuvant in Colorectal Cancer

Case 2. Green Tea Polyphenols in Prostate Cancer Management

Case 3. Resveratrol in Pancreatic Cancer.

Case 4. Omega-3 Fatty Acids in Colorectal Cancer Prevention

Case 5. Quercetin in Lung Cancer Supportive Care

Case 6. Lycopene in Prostate Cancer Progression

Case 7. Flavonoids in Breast Cancer Survivorship

Case 8. Garlic Compounds in Colorectal Cancer Prevention

Case 9. Polyphenols in Esophageal Cancer Prevention

Case 10. Mediterranean Diet in Multiple Myeloma Management

Clinical Trials and Evidence-Based Insights

Sulforaphane and Breast Cancer

Curcumin's Role in Colorectal Cancer

Green Tea Polyphenols in Prostate Cancer

Resveratrol in Pancreatic Cancer

Lycopene in Prostate Cancer Prevention

Omega-3 Fatty Acids in Colorectal Adenoma Recurrence

Quercetin for Lung Cancer Support

Garlic in Colorectal Cancer Prevention

Regulatory and Ethics Concerned with Culinary Cures

Regulatory Oversight

Navigating The Intersection of Food and Medicine

Ethical Implications

Informed Consent and Patient Autonomy

Standardization and Quality Control

Addressing Variability in Dietary Compounds

Integrative Care Models

Navigating Collaborative Approaches

Addressing Vulnerability

Ensuring Equitable Access and Protection

Chapter 9

Medicinal Mushrooms for Cancer Support

Immunomodulatory Action of Mushrooms in Cancer Management

Anti-Inflammatory Action of Mushrooms in Cancer Management

Antioxidant Potential of Mushrooms in Cancer Management

Apoptosis Effect of Mushrooms in Cancer Management

Mushrooms Shown to Have Anticancer Potential

Ganoderma Lucidum

Trametes Versicolor

Lentinula Edodes

Grifola Frondosa

Agaricus Sylvaticus

Side-Effects of Mushrooms in Cancer Management

Chapter 10

Essential Oils in Cancer Treatment

Abbreviations.

Introduction.

Notes:

Description based on publisher supplied metadata and other sources.

Other Format:

Print version: Guarve, Kumar Nature's Arsenal Against Cancer: Harnessing the Power of Natural Compounds for Treatment and Prevention

ISBN:

9798895302279

OCLC:

1478698816