Liver Cancer - Genesis, Progression and Metastasis / Mark Feitelson, Alla Arzumanyan, editors.

Format:

Book

Contributor:

Feitelson, Mark, editor.

Arzumanyan, Alla, editor.

Language:

English

Subjects (All):

Oncology.

Cancer--Psychological aspects.

Cancer.

Physical Description:

1 Online-Ressource (146 pages)

Place of Publication:

London : IntechOpen, 2023.

Summary:

Hepatocellular carcinoma (HCC) is a common tumor type arising from several distinct etiologies. It is usually diagnosed late and is difficult to treat. This volume presents an overview of selected aspects of HCC pathogenesis, and research aimed at developing diagnostic biomarkers. It points to a number of putative therapeutic targets, including signal transduction pathways, metabolic and epigenetic alterations in tumor cells, the tumor microenvironment, the gut microbiome, and functions of immune effector cells. Given the multi-step nature of most cancers, including HCC, future drug development will most likely require combination therapies that will simultaneously target multiple steps in hepatocarcinogenesis.

Contents:

1. Etiology, Mechanism and Treatment of Liver Cancer

By Aqsa Nazir, Muhammad Aqib and Muhammad Usman

2. Non-alcoholic Fatty Liver Disease Associated Hepatocellular Carcinoma

By Kai Sun, Alan Hodges and Maen Abdelrahim

3. Hepatic Progression of Hepatocellular Carcinoma

By Anna Rossetto, Alessandro Rosignoli, Brunilda Tatani, Valli De Re and Alessandro Uzzau

4. Role of Biomarkers in Hepatocellular Carcinoma and Their Disease Progression

By S.S. Haque, Ravi Bhushan Raman and Mehboobus Salam

5. miRNAs in Liver Cancer

By Alisa Petkevich, Aleksandr Abramov and Vadim Pospelov

6. Emerging Immunotherapy: Liver Cancer Microenvironment for Treatment

By Shihai Liu

7. Mechanisms of Hepatocarcinogenesis Development in an Acidic Microenvironment

By Cheng Jin, You-Yi Liu and Bo-Shi Wang.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

1-80356-414-8