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Brain tumors and the Lynch syndrome.
- Format:
- Book
- Author/Creator:
- Peltomäki, Päivi, author.
- Language:
- English
- Subjects (All):
- Brain--Tumors--Genetic aspects.
- Brain.
- Colon (Anatomy)--Cancer--Genetic aspects.
- Colon (Anatomy).
- Colon (Anatomy)--Cancer--Cytopathology.
- Rectum--Cancer--Genetic aspects.
- Rectum.
- Physical Description:
- 1 online resource (chapter 15, pages [363]-382) : illustrations; digital file(s).
- Place of Publication:
- IntechOpen 2011
- Language Note:
- English
- System Details:
- text file
- Summary:
- Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003).
- Notes:
- Includes bibliographical references.
- ISBN:
- 953-51-6503-8
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