RNA Interference / edited by Ibrokhim Y. Abdurakhmonov.

Format:

Book

Contributor:

Abdurakhmonov, Ibrokhim Y., editor.

Language:

English

Subjects (All):

Medical genetics.

Physical Description:

1 online resource (458 pages) : illustrations

Place of Publication:

[Rijeka, Croatia] : IntechOpen, 2016.

Summary:

RNA interference (RNAi), a hallmark of all biological sciences of twenty-first century, is an evolutionarily conserved and double-stranded RNA-dependent eukaryotic cell defense process. Opportunity to utilize an organisms own gene and to systematically induce and trigger RNAi for any desired sequence made RNAi an efficient approach for functional genomics, providing a solution for conventional longstanding obstacles in life sciences. RNAi research and application have significantly advanced during past two decades. This book RNA interference provides an updated knowledge and progress on RNAi in various organisms, explaining basic principles, types, and property of inducers, structural modifications, delivery systems/methodologies, and various successful bench-to-field or clinic applications and disease therapies with some aspects of limitations, alternative tools, safety, and risk assessment.

Notes:

Description based on print version record.

Includes bibliographical references.

ISBN:

9789535154297

953515429X