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Revolutionizing reproduction the ethical landscape of in vitro gametogenesis edited by Christopher Gyngell, Julian Savulescu, Tsutomu Sawai

Oxford Scholarship Online: Philosophy Available online

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Format:
Book
Contributor:
Gyngell, Christopher, editor.
Savulescu, Julian, editor.
Sawai, Tsutomu, 1986- editor.
Language:
English
Subjects (All):
Fertilization in vitro, Human--Moral and ethical aspects.
Fertilization in vitro, Human.
Gametogenesis--Moral and ethical aspects.
Gametogenesis.
Medical Subjects:
Gametogenesis.
Physical Description:
1 online resource
Edition:
1st ed.
Other Title:
Ethical landscape of in vitro gametogenesis
Place of Publication:
Oxford University Press, 2026.
New York, NY Oxford University Press [2026]
Summary:
'Revolutionizing Reproduction' explores the rapidly advancing field of in vitro gametogenesis (IVG) - the generation of sperm and eggs from somatic or stem cells in the laboratory - and its profound implications for science, ethics, and society
Contents:
Cover
Half Title
Title Page
Copyright Page
Contents
Preface
List of Contributors
Introduction-Are We Ready for a Revolution?
1 In Vitro Gametogenesis: Creation of Gametes in a Dish
Outline of Germ Cell Development in Mammals
Prototype of IVG: Organ Culture of Gonads
Prototype of IVG: Spontaneous Differentiation of Germ Cells from Pluripotent Stem Cells
PGC Derivation from Pluripotent Stem Cells in Model Animals
PGC Derivation from Human and Non-Human Primate Pluripotent Stem Cells
PGC Derivation from Pluripotent Stem Cells in Large Mammals
Gamete Production from Mouse PGCLCs
Progress Towards the Production of Human Gametes Through IVG
Perspectives
Bibliography
2 Reproduction without Constraints: How IVG Will Reshape Reproduction
The Emergence of Sex
Constraint 1: Needing to Find a Mate (of the Opposite Sex)
Solo Reproduction
Same-Sex Reproduction
Constraint 2: The Need for Functional Reproductive Systems
Restoring Fertility
Reproduction in Old Age
Reproduction in Youth
Posthumous Reproduction
Constraint 3: Limited Oocyte Supply
Improved Selection
Iterative Embryo Selection
Constraint 4: Sex Is Limited to Two Organisms
Conclusion
3 IVG and Relational Procreative Autonomy
Introduction
Potential Clinical Uses of IVG
A Relational Conception of Procreative Autonomy
Relational Autonomy
Relational Procreative Autonomy
Reproductive Uses of IVG and Relational Procreative Autonomy
Same-Sex IVG
Solo IVG
Multiplex IVG
Additional Threats to Procreative Autonomy
Enhancing Reproductive Selection
4 Sex and Gender Minorities and In Vitro Gametes: Ethics, Access, and Status Equality
Who Should Benefit from In Vitro Gametes?
Infertility and Infertility Distress as Justification for Entitlement to IVG
Presupposing and Reinforcing the Objectionable Value of Geneticism
ARTs in General Confer Status Equality on SSQ Couples
Conclusions
5 Eugenics under the Microscope
In Vitro Eugenics
Selection and Conception of Human Beings In Vitro
Eugenics: What's in a Name?
Eugenics and Its History
What's Wrong with Eugenics?
'Iterated Embryo Selection'? Or 'In Vitro Eugenics'?
The Ethics of In Vitro Eugenics
Lessons for Other Reproductive Technologies . . . and for Bioethicists
6 Respecting Offspring
Identifying Parents: When Is In Vitro Gametogenesis (Truly) Parental?
Respectful Parental Conception
Restoring Reproductive Health: IVG with Autologous Transplantation
Mass-Production and Polygenic Screening
Unparental Parenthood
Respect for Embryos
Unconditional Acceptance
Multiplex Reproduction
Genetic Parents and Nonparents
Social Parents and Nonparents
Multiplex IVG Offspring
Outcomes for/Reactions of IVG and Other ART Offspring
Bibliography
Notes:
Includes bibliographical references and index
Description based on online resource; title from digital title page (viewed on May 14, 2026)
Other Format:
Print version :
ISBN:
9780197810415
0197810411
OCLC:
1582307762
Publisher Number:
CIPO000373987
Access Restriction:
Restricted for use by site license

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