Transketolases / edited by Franck Charmantray, Bastien Doumèche.

Format:

Book

Contributor:

Charmantray, Franck, editor.

Doumèche, Bastien, editor.

Series:

Methods in enzymology ; 0076-6879 v. 722.

Methods in enzymology, 0076-6879 ; volume 722

Language:

English

Subjects (All):

Transketolase.

Transketolase--metabolism.

Transketolase--antagonists & inhibitors.

High-Throughput Screening Assays--methods.

Medical Subjects:

Transketolase--metabolism.

Transketolase--antagonists & inhibitors.

High-Throughput Screening Assays--methods.

Physical Description:

xxviii, 491 pages : illustrations ; 23 cm.

Edition:

First edition.

Place of Publication:

Cambridge, MA : Academic Press, an imprint of Elsevier, 2025.

Contents:

Contributors

Preface

1. Role of transketolase-like1 in human cortical neurogenesis / Anneline Pinson and Wieland B. Huttner

2. Transketolase in metabolic diseases, autoimmune diseases and cancer / Zhangbing Chen, Yi Wang, and Xuemei Tong

3. Evaluation of binding, affinity and metabolic regulatory activity of a transketolase inhibito / Dan Jia, Chunliang Liu, Wenyu Liu, Jing Fu, Xiaofei CHen, and Hong-yang Wang

4. Validation of the robust performance of novel transketolase epitopes for tuberculosis immunodiagnostics / Jaya Talreja, Brennen Steinbauer, and Lobelia Samavati

5. Function and therapeutic potential of transketolase enzymes in parasitic protists / Ningbo Xia and Nishith Gupta

6. Electrochemical screening as a tool for identification of transketolase inhibitors / Chloé M.G. Aymard, Rainier-Numa Georges, Florian Bianco, Jean-Francois Chateaux, Franck Charmantray, and Bastien Dournèche

7. Methods for studying plant transketolases / Dorothea Bartles

8. Identification and functional characterization of transketolases in sulfoglycolytic pathways / Jiayi Liu, Yan Zhang, and Nathcar Naowarojna

9. A split-gene transketolase essential for phosphonothrixin biosynthesis / Yuxun Zhu and Tomohisa Kuzuyama

10. Biophysical and structural studies on transketolases / Fabian Rabe von Pappenheim and Kai Tittman

11. Structural variations of transketolases over the evolution from bacteria to higher eukaryotes : in silico/in vitro study / Rainier-Numa Georges, Lionel Ballut, Franck CHarmantray, and Bastien Doumèche

12. Transketolase catalytic reaction pathway. Study of thiamine diphosphate activation and complete catalytic cycle / Vincent Thery and Lionel Nauton

13. Transketolase : mechanistic aspects from QM and QM/MM investigations / Alessia Dodaro, Mario Prejanò, Fabiola E. Medina, Nino Russo, and Tiziana Marino

14. Transketolase enzyme discovery and engineering / Alessia Tonoli, Paul ANthony Dalby, Helen Claire Hailes, and Jack William Edward Jeffires

15. Evolved thermostable transketolase from Geobacillus stearothermophilus for the synthesis of deoxyketoses / Camille Gadona, Giuseppe Arbia, Muriel Joly, Franck Charmantray, and Laurence Hecquet

16. Practical high-throughput screening assays to engineer the substrate scope of transketolase variants / Jules Perrard and Wolf-Dieter Fessner

17. Production of rare sugars by transketolase in combination with ketose 3-epimerase / Akihide Yoshihara, Yusuke Hanaki, Susumu Mochizuki, Hiromi Yoshida, Ken Izumori, and Shigehiro Kamitori

18. Engineering transketolase for stereoselective a-hydroxyketone synthesis / Xianqi Yin, Qi Liu, Tingting Huang, and Shuangjun Lin

19. Process considerations for the implementation and scale-up of transketolase-catalyzed biocatalytic processes / John M. Woodley.

Notes:

Includes bibliographical references.

Other Format:

ebook version :

ISBN:

9780443430510

0443430519

OCLC:

1518267632

Publisher Number:

CIPO000301334