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Improving the Availability of Unrelated Stem Cell Donors: Evidence from a Major Donor Registry / Michael Haylock, Patrick Kampkötter, Mario Macis, Jürgen Sauter, Susanne Seitz, Robert Slonim, Daniel Wiesen, Alexander H. Schmidt.
- Format:
- Book
- Author/Creator:
- Haylock, Michael.
- Series:
- Working Paper Series (National Bureau of Economic Research) no. w29857.
- NBER working paper series no. w29857
- Language:
- English
- Physical Description:
- 1 online resource: illustrations (black and white);
- Place of Publication:
- Cambridge, Mass. National Bureau of Economic Research 2022.
- Summary:
- The unavailability of potential stem cell donors poses a critical challenge for donor registries worldwide. This study investigates the impact of initiatives of a stem cell donor registry to enhance donors' availability for confirmatory typing. Initiatives ask donors to provide a sample for genetic analysis and/or information on their temporal unavailability. We analyzed 91,479 confirmatory typing requests from DKMS Germany, a large stem cell donor registry, exploiting a quasi-random initiative assignment based on observable characteristics. We find that, first, invitation to the initiatives increases donors' availability. Intention-to-treat estimates yield effects ranging from 2.5 to 3.2 percentage points, and local average treatment effects estimates range from 3.8 to 8.2 percentage points (baseline: 77.1%). Second, the difference in availability between participants and non-participants is over 10 percentage points. The initiatives yield a direct positive effect on donor availability and a selection effect through which participation signals a higher commitment.
- Notes:
- Print version record
- March 2022.
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