Guidance Document for the scientific review of Adverse Outcome Pathways / OECD.

Format:

Book

Author/Creator:

Organisation for Economic Co-operation and Development, author, issuing body.

Series:

OECD series on testing and assessment.

OECD Series on Testing and Assessment

Language:

English

Subjects (All):

Chemical tests and reagents.

Physical Description:

1 online resource (23 pages).

Place of Publication:

Paris : OECD Publishing, 2021.

Summary:

The Adverse Outcome Pathway (AOP) framework has been developed to facilitate the collection of mechanistic information derived from toxicological science in a structured manner, to assist in establishing causal relationships between molecular and cellular events that lead from stressor perturbation of the biology to adverse effects, and to identify critical data gaps in the understanding of those pathways. The objective of the present document is to provide guidance on the quality standards required for the scientific review of an AOP on the AOP-Wiki. It defines the core principles associated with AOP scientific review in order to enable consistent scientific reviews to be conducted, regardless of who is doing the review, and thus will facilitate OECD endorsement.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

92-64-91515-X