Guidance Document on Pesticide Residue Analytical Methods / OECD.

Format:

Book

Author/Creator:

Organisation for Economic Co-operation and Development, author, issuing body.

Series:

Series on Pesticides and Biocides

Language:

English

Subjects (All):

Pesticide residues in food--Analysis.

Pesticide residues in food.

Physical Description:

1 online resource (34 pages).

Place of Publication:

Paris : OECD Publishing, 2017.

Summary:

This document provides guidance on the residue analytical methods. Analytical methods are used to generate the data for estimating dietary exposure assessments, to establish Maximum Residue Levels (MRLs), and to determine processing factors. Analytical methods are also used in enforcement of any statutory MRLs that may be established. Methods apply to all pesticides used on edible crops/livestock and subsequent produce and processed food products, and for products (e.g. meat, milk, eggs) from animals that may consume treated crops. Additionally, analytical methods are needed for conducting storage stability studies.

Contents:

ABOUT THE OECD

FOREWORD

INTRODUCTION

PURPOSE

DEFINITION OF VALIDATION PARAMETERS

Recovery

Selectivity (Specificity)

Calibration

Repeatability

Reproducibility

Limit of Detection (LOD)

Limit of quantitation (LOQ)

GENERAL ASPECTS

Analytes Under Consideration

Extraction Efficiency / Radio-Validation

Confirmatory Techniques

Derivatization

Common Moiety Methods and Non-Specific Methods

VALIDATION OF PRE-REGISTRATION METHODS

Number of Matrices for Validation

Validation Levels

Number of Fortification Experiments

Use of Internal and Procedural Standards

METHODS FOR MRL ENFORCEMENT (POST REGISTRATION)

Independent Laboratory Validation Studies (Post-Registration)

Number of Representative Matrices for Independent Validation

Validation Levels for ILVs: Limit of Quantitation - Maximum Residue Levels

MINIMUM PERFORMANCE CHARACTERISTICS FOR METHODS

Range of Acceptable Recoveries

Selectivity (Matrix Interference)

Precision - Repeatability (expressed as relative standard deviation)

STABILITY INVESTIGATIONS

Stability of the Analytes in Stored Extracts of the Final Volume

Stability of Working (Fortification/Calibration) Solutions

STUDY REPORT

REFERENCES

ANNEX 1 COMMODITY CATEGORIES FOR PRE- AND POST-REGISTRATION METHOD VALIDATION.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

92-64-88043-7