Guidance Document on the Definition of Residue, First edition / OECD.

Format:

Book

Author/Creator:

Organisation for Economic Co-operation and Development, author, issuing body.

Series:

Series on Pesticides and Biocides

Language:

English

Subjects (All):

Pesticide residues in food--Analysis.

Pesticide residues in food.

Physical Description:

1 online resource (34 pages).

Place of Publication:

Paris : OECD Publishing, 2006.

Summary:

The harmonised Guidance for the Definition of Residue provides a common approach to residue identification of the pesticide and its metabolites. Residue analysis for dietary risk assessment emphasises analysis of the parent compound and its most significant metabolites, taking into consideration both exposure and relative toxicities. Residue analysis for tolerance/MRL enforcement purposes focuses on those 'analytes' which would indicate a possible misuse of the pesticide and which also can be detected and measured by a broad base of national laboratories, i.e., residues which are easy to measure and which occur in large quantities. The Guidance Document on the Definition of Residue balances these concerns so that the appropriate chemical moieties can be analysed. It differentiates residue definitions for data generation and risk assessment purposes versus MRL/tolerance-setting and enforcement purposes. Such guidance will be available to pesticide applicants so that they may propose definitions of residue for each purpose and provide data for implementation.

Contents:

ABOUT THE OECD

FOREWORD

Introduction

General Considerations

Residue Definition for Dietary Risk Assessment

Potential for Exposure

Toxicity Considerations for Metabolites/Degradates

Separate Assessments for Metabolites and Degradates

Combining Exposure and Toxicity Considerations

Residue Definition for MRL Setting/Tolerance Expression

Principles for Establishing a Residue Definition for Setting MRLs/tolerances

Residue Definition for MRL Setting and Risk Assessment in the Case of Isomers

BIBLIOGRAPHY

ANNEX 1 DATABASES ON TOXICOLOGY

ANNEX 2 OECD EXPERT GROUP ON PESTICIDE RESIDUE CHEMISTRY

List of Tables.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

92-64-61542-3