Real Time Sampling and Analysis of Biological Biomarkers by TOF Mass Spectrometry Johns Hopkins University

Format:

Conference/Event

Author/Creator:

Antoine, Miquel D., author.

Conference Name:

International Conference On Environmental Systems (1998-07-13 : Danvers, Massachusetts, United States)

Language:

English

Physical Description:

1 online resource

Place of Publication:

Warrendale, PA SAE International 1998

Summary:

We are developing and testing a small, efficient time-of-flight mass spectrometer to rapidly identify importantbiomarkers for human space exploration. We are also evaluating critical biomarkers that are indicators of muscle atrophy and bone demineralization associated with space travel. We have recorded mass spectral signatures of several biomarkers. Compounds under investigation include: insulin-like growth factors (IGF-I), urinary 3-methylhistidine, estradiol, and creatinine. We have also completed initial studies of trivalent hydroxypyridinium crosslinks which are excreted as free pyridinolines in urine during bone resorption

Notes:

Vendor supplied data

Publisher Number:

981740

Access Restriction:

Restricted for use by site license