Evaluation of the Risk of Circulating Microbubbles Under Simulated Extravehicular Activities After Bed Rest NASA Johnson Space Center

Format:

Conference/Event

Author/Creator:

Vasantha Kumar, K., author.

Conference Name:

International Conference On Environmental Systems (1993-07-12 : Colorado Springs, Colorado, United States)

Language:

English

Physical Description:

1 online resource

Place of Publication:

Warrendale, PA SAE International 1993

Summary:

This ground-based study compared the risk of microbubbles during decompression under simulated space extravehicular activities (EVA) after three days of six-degree head-down bed rest with three days of ambulatory control. Test subjects were exposed to a pressure of 44.8 kPa (6.5 psi), breathed 100% oxygen, and exercised at reduced pressure either in the supine (during experimental) or upright (control) position. Circulating microbubbles were monitored by a precordial Doppler ultrasound device, and were found in 52% (12/23) of control and 26% (6/23) of experimental exposures. Survival analysis using Cox proportional hazards regression showed that there was 0.22 times (95% confidence interval=0.07-0.68) reduction in the risk of high grade microbubbles after bed rest, compared to controls (p=0.004). This finding is of importance in evaluating the risk of DCS during EVA

Notes:

Vendor supplied data

Publisher Number:

932220

Access Restriction:

Restricted for use by site license