Glioblastoma and New Therapeutic Drugs and Approaches.

Format:

Book

Author/Creator:

Alexiou, Athanasios, author.

Language:

English

Subjects (All):

Chemotherapy.

Immunosuppression.

Physical Description:

1 online resource (452 pages)

Edition:

1st ed.

Place of Publication:

Hershey : IGI Global Scientific Publishing, 2025.

Summary:

Glioblastoma is the most aggressive and lethal form of primary brain tumor in adults, characterized by rapid growth, high invasiveness, and resistance to conventional therapies. Current treatment options offer limited survival benefits. However, recent advancements in molecular biology, genomics, and drug delivery systems pave the way for more effective, targeted therapeutic strategies. Emerging approaches include immunotherapy, gene editing, and personalized medicine. Novel drug candidates and repurposed agents are explored in clinical trials, overcoming the blood-brain barrier and targeting specific mutations driving glioblastoma progression. These evolving therapies may improve outcomes and transform the future landscape of glioblastoma treatment. Glioblastoma and New Therapeutic Drugs and Approaches explores glioblastoma and new therapeutic drugs under development. It examines innovative treatment modalities, drug delivery regimens, and therapeutic strategies to address glioblastoma care. This book covers topics such as nanomaterials, chemistry, and medical diagnosis, and is a useful resource for medical and healthcare professionals, engineers, drug developers, oncologists, academicians, researchers, and scientists.

Contents:

Title Page

Copyright Page

Table of Contents

Detailed Table of Contents

Preface

Chapter 1: Current Treatment Modalities Associated With Glioblastoma and Its Merits and Demerits

Chapter 2: Current Challenges and Significant Innovations for Glioblastoma

Chapter 3: DNA Lesions and Double-Strand Breaks for Glioblastoma

Chapter 4: Drug Regimens Used for Glioblastoma

Chapter 5: Resistance Mechanism of Chemotherapeutic Agents Using Nanotheranostic Approach

Chapter 6: In-Vitro and In-Vivo Models for Glioblastoma

Chapter 7: Drugs Under Clinical and Pre-Clinical Research for Glioblastoma

Chapter 8: Drug Repurposing and Overcoming the Blood-Brain Barrier for Glioblastoma

Chapter 9: Novel Drug Delivery and Dosage Forms for Glioblastoma

Chapter 10: Nanomaterial-Based Strategies for Overcoming the Blood-Brain Barrier in Glioblastoma Therapy

Compilation of References

About the Contributors

Index.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

979-83-373-2698-6

979-83-373-2697-9

OCLC:

1569118850