Glucose Oxidase : Structure, Properties and Applications / Gitashree Darabdhara, editor.

Format:

Book

Contributor:

Darabdhara, Gitashree, editor.

Series:

Life Sciences Research and Development Series

Language:

English

Subjects (All):

Oxidoreductases.

Physical Description:

1 online resource (316 pages)

Edition:

First edition.

Place of Publication:

New York : Nova Science Publishers, Inc., [2023]

Summary:

"This book gives an overview of glucose oxidase, its properties, and applications in the area of industrial and biotechnological arenas with special reference to its catalytic role in the detection of glucose biomolecule for diabetes management. The book emphasizes the properties of nanostructured materials that can be coupled with glucose oxidase in providing a stimulating podium for the detection of important biomolecule glucose"-- Provided by publisher.

Contents:

Intro

Contents

Preface

Chapter 1

An Introduction to Glucose Oxidase

Abstract

1. Introduction

2. Source and Properties of GOD Family Enzymes

3. Crystal Structure and Catalytic Mechanism of GOD

4. Applications of Glucose Oxidase

4.1. Food Industry

4.2. Sensor Industry

4.3. Animal Feed Addition

4.4. Pharmaceutical Industry

4.5. Developing Biofuels

4.6. Application of Its Reaction By-Products

5. Microbial Fermentation Production of Glucose Oxidase

6. GOD Enzyme Molecular Modification

7. Immobilization of Glucose Oxidase

Conclusion

References

Chapter 2

An Introduction to Enzymatic and Non-Enzymatic Glucose Biosensors Based on Glucose Oxidase

1.1. Applications of Biosensors

1.2. Role of Biosensors in the Modern Biomedical Field

1.3. Advantages of Biosensors

2. Enzymatic Biosensors of Glucose Oxidase

2.1. Conventional Enzyme-Based Biosensors

2.1.1. Electrochemical Enzyme-Based Biosensors

2.1.1.1. Amperometric Biosensors

2.1.1.1.1 The First-Generation Glucose Biosensors or Classical Enzymatic Biosensors

2.1.1.1.2. The Second Generation or Mediator-Based Glucose Biosensors

2.1.1.1.3. The Third Generation or Mediator-Free Enzymatic Glucose Biosensors

2.1.1.2. Potentiometric Biosensors

2.1.1.3. Impedimetric Biosensors

2.1.2. Optical Biosensors

2.1.3. Piezoelectric Biosensors

2.2. Non-Invasive-Based Glucose Biosensors

2.2.1. Nanomaterial-Based Glucose Biosensors

2.2.2. Conducting Polymer-Based Glucose Biosensors

3. Non-Enzymatic Glucose Oxidase Biosensors

3.1. Current Scenario of Enzyme-Free Glucose Biosensors

3.2. Advantages of Non-Enzymatic Glucose Biosensors

3.2.1. Stability

3.2.2. Simplicity and Reproducibility

3.2.3. Free from Oxygen Limitations

3.2.3.1. Activated Chemisorption Model.

3.2.3.1.1. Mechanism

3.2.3.2. Incipient Hydrous Oxide Adatom Mediator Model

3.2.3.2.1. Pre-Monolayer Oxidation of Metals

3.2.3.2.2. Incipient Hydrous Oxide Role in Electro-Catalysis

4. Glucose Biosensors Based on Metals

4.1. Zinc-Based Electrodes

4.2. Platinum-Based Electrodes

4.3. Copper Oxide-Based Electrodes

5. Recent Advances in Biosensors

Chapter 3

Enzyme-Immobilized 2D Nanosheets for the Detection of Glucose

2. Sensing Mechanism of Enzymatic Glucose Sensors

3. 2D Materials for Electrochemical Glucose Sensing

3.1. Enzymatic Glucose Sensors Based on Graphene

3.2. Enzymatic Glucose Sensors Based on MXene

3.3. Enzymatic Glucose Sensors Based on Transition Metal Dichalcogenides (TMD)

3.4. Enzymatic Glucose Sensors Based on LDH

Chapter 4

Non-Enzymatic Graphene-Based Electrodes for Glucose Sensing

2. Enzymatic and Non-Enzymatic Glucose Biosensors

3. Generation of Enzyme-Based Glucose Biosensors

3.1. First Generation Glucose Biosensors

3.2. Second Generation Glucose Biosensors

3.3. Third Generation Glucose Biosensors

4. Types of Electrodes in Non-Enzymatic Glucose Sensors

4.1. Platinum Electrodes

4.2. Gold Electrodes

4.3. Non-Precious Transition Metal-Based Electrodes

4.4. Metal Alloy, Adatoms, and Bimetallic-Based Electrodes

4.5. Carbon-Based Electrodes

4.6. Carbon Nanotube (CNT)-Based Electrodes

4.7. Graphene-Based Electrodes

5. Non-Enzymatic Graphene-Based Glucose Sensors

5.1. Graphene-Based Electrodes/Precious Metal Nanostructures

5.2. Graphene-Based/Non-Precious Metal Nanostructure Electrodes

5.3. Graphene Composites Based on Alloy/Metal/Bimetallic Hybrid Nanostructures

5.4. Graphene-Heterodoping Composites.

5.5. Graphene-Based Electrodes with Polymers

6. Future Trends

Chapter 5

Metal Oxide Nanoparticles-Based Glucose Biosensors

2. Metal Oxide/Graphene Nanocomposites for Glucose Biosensors

3. Methods for the Synthesis of Metal Oxides/ Graphene Nanocomposites

3.1. Zinc Oxide/Graphene Nanostructures-Based Glucose Biosensors

3.2. Copper Oxide/Graphene Nanostructures-Based Glucose Biosensors

3.3. Titanium Oxide/Graphene and Some Other Metal Oxide/Graphene Nanostructures-Based Glucose Biosensors

Chapter 6

Metal Nanoparticle-Based Glucose Biosensors

2. Components of Glucose Biosensor

2.1. The Biological Recognition Element (Sensor/Detector)

2.1.1. Receptors

2.1.2. Enzymes

2.1.3. Antibodies

2.1.4. Nucleic Acids

2.2. Transducers

2.2.1. Electrochemical Biosensors

2.2.2. Optical Biosensors

2.2.3. Piezoelectric Biosensors

2.2.4. Magnetic Biosensors

2.3. Electrical Circuits

3. Important Enzymes in Glucose Metabolism

3.1. Hexokinase

3.2. Glucose Oxidase (GOx)

3.3. Glucose-1-Dehydrogenase (GDH)

4. The Basic Principles of Glucose Biosensors

5. Metal Nanoparticle-Based Glucose Biosensors

5.1. Gold Nanoparticles (AuNPs)

5.2. Silver Nanoparticles (AgNPs)

5.3. Platinum Nanoparticles (PtNPs)

5.4. Copper Nanoparticles (CuNPs)

5.5. Bimetallic Nanocomposites/Systems

5.6. Other Metal Nanoparticles

6. Nanostructured Metal-Oxide Based Glucose Biosensors

6.1. Nanostructured Zinc Oxide (ZnO) as a Glucose Biosensor

6.2. Copper Oxide (CuO/Cu2O)-Based Glucose Biosensors

6.3. Manganese Dioxide (MnO2)-Based Glucose Biosensors

6.4. Titanium Dioxide (TiO2)-Based Glucose Biosensors

6.5. Cerium Oxide (CeO2)-Based Glucose Biosensors.

6.6. Silicon Dioxide (SiO2)-Based Glucose Biosensors

6.7. Zirconium Oxide (ZrO2)-Based Glucose Biosensors

6.8. Other Metal Oxides

Chapter 7

Glucose Oxidase-Based Electrochemical Biosensors for the Detection of Glucose

2. Sources and Industrial Production of GOx

3. Structure of Glucose Oxidase

4. Mechanism of Glucose Sensing by GOx

4.1. First Generation Biosensors

4.2. Second Generation Biosensors

4.3. Third Generation Biosensors

5. Parameters/Terms Used in Glucose Sensors

5.1. Sensitivity

5.2. Linearity and Linear Range

5.3. Response Time

5.4. Selectivity

5.5. Immobilization

6. Historical Aspects and Present Applications of Glucose Oxidase as Glucose Biosensors

6.1. Other Applications

Chapter 8

Graphene and Carbon Nanotubes as Glucose Sensors

2. History of Glucose Sensors

3. Graphene as Glucose Sensors

3.1. Structures and Properties of Graphene Suitable for Glucose Sensing

3.2. Graphene-Based Enzymatic Sensors

3.3. Graphene-Based Non-Enzymatic Sensors

4. Carbon Nanotubes as Glucose Sensors

4.1. Structures and Properties of Carbon Nanotubes Suitable for Glucose Sensing

4.2. Carbon Nanotube-Based Enzymatic Sensors

4.3. Carbon Nanotube-Based Non-Enzymatic Sensors

Chapter 9

Carbon Nanomaterial-Based Sensors for Diabetes Diagnostics

2. Carbon Nanomaterials

2.1. Graphene

2.2. Fullerene

2.3. Carbon Nanotubes

2.3.1. Single-Walled Carbon Nanotubes

2.3.2. Multi-Walled Carbon Nanotubes

2.4. Carbon Dots

2.5. Others

3. Synthesis of Carbon Nanomaterials

4. Carbon Nanomaterial-Based Electrochemical Glucose Sensors.

4.1. Carbon Nanomaterials for Enzymatic Glucose Sensing

4.1.1. Enzymatic Glucose Sensing Mechanisms

4.1.1.1. First Generation Biosensors

4.1.1.2. Second Generation Biosensors

4.1.1.3. Third Generation Biosensors

4.1.2. Immobilization of Glucose Oxidase on Carbon Nanomaterials

4.1.2.1. Physical Adsorption Method

4.1.2.2. Covalent Linkage Method

4.1.2.3. Crosslinking Method

4.1.2.4. Polymer Entrapment

4.1.3. Carbon Nanomaterial-Based Non-Enzymatic Electrochemical Glucose Sensors

5. Carbon Nanomaterial-Based Optical Glucose Sensors

5.1. Carbon Dots

5.2. Single-Walled Carbon Nanotubes (SWCNT)

5.3. Others

Chapter 10

Glucose Oxidase Catalyzed Glucose Oxidation for the Detection of Cancer Biomarkers

2. General Principles of GOx-Based Diagnosis in Cancer

2.1. Oxygen-Based Sensors

2.2. pH-Sensitive Biosensors

2.3. H2O2-Dependent Biosensors

2.3.1. H2O2-Based Photo-Electrochemical Immunosensing

3. Classification of GOx Based on the Type of Materials

3.1. Metallic NPs-Based GOx Biosensors

3.2. Non-Metallic GOx Biosensors

4. GOx-Based Materials for Cancer Theranostics

4.1. Starvation Therapy of Cancer Based on Glucose Oxidase Nanogels

4.1.1. Polymeric Nanogel

4.1.2. Dendritic Mesoporous Organosilicon Nanoparticles

4.1.3. Glucose Dual-Response Cascading Hydroxyl Radical Generation In Situ Gelation Therapy

4.1.4. Metal-Organic Framework with Glucose Oxidase Loaded on a Cu2+ Therapy

4.1.5. Dual-Drug Multifunctional Theranostic Nanoparticles with Synergistic Sonodynamic Therapy

5. Other Strategies

5.1. Receptor-Mediated Therapies

5.2. Antioxidant-Based Therapies

5.3. Hypoxia-Related Cancer Therapies

5.4. Enzyme-Related Cancer Therapies

Index

About the Editors.

Blank Page.

Notes:

Description based on print version record.

Includes bibliographical references and index.

Other Format:

Print version: Darabdhara, Gitashree Glucose Oxidase: Structure, Properties and Applications

ISBN:

979-88-86978-77-3