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Voriconazole : pharmacokinetics, role in therapeutic drug monitoring and clinical outcomes / Andrea Angelini, editor ; contributors, Daoud Al-Badriyeh [and sixteen others].
- Format:
- Book
- Series:
- Pharmacology-research, safety testing, and regulation series.
- Pharmacology-Research, Safety Testing, and Regulation
- Language:
- English
- Subjects (All):
- Pharmacokinetics.
- Physical Description:
- 1 online resource (202 p.)
- Place of Publication:
- New York : Nova Biomedical, 2015.
- Language Note:
- English
- Summary:
- In the last twenty years, the incidence of invasive fungal infections (IFI) has risen dramatically due to the prolongation of survival of patients with multiple risk factors for fungal infections and due to the increase of infection associated with travel. Moreover IFI in infants admitted to the neonatal intensive care unit are common and often fatal. Amphotericin B was for more than 40 years the gold standard for almost all IFI, but toxicity and resistance, especially of new and emerging pathogens remained important issues. Fluconazole and itraconazole have also the same disadvantage of resis
- Contents:
- VORICONAZOLE: PHARMACOKINETICS, ROLE IN THERAPEUTIC DRUG MONITORING AND CLINICAL OUTCOMES; VORICONAZOLE: PHARMACOKINETICS, ROLE IN THERAPEUTIC DRUG MONITORING AND CLINICAL OUTCOMES; Library of Congress Cataloging-in-Publication Data; Contents; Preface; List of Contributors; PART I; Chapter 1: Voriconazole: Synthesis and Mechanism of Action; Chapter 2: Action of Voriconazole In Vitro and In Vivo; Chapter 3: Voriconazole: Pharmacokinetics, Dosage and Administration; PART II; Chapter 4: Antifungal Therapy with Voriconazole for Aspergillosis
- Chapter 5: Voriconazole Treatment in Invasive CandidiasisChapter 6: Antifungal Therapy with Voriconazole for Esophageal Candidiasis; Chapter 7: Voriconazole in Orthopaedics: Osteomyelitis and Antifungal-Loaded Bone Cement; Chapter 8: Voriconazole for Endemic Fungal Infection(Disseminated Histoplasmosis, Blastomycosis, Coccidioidomycosis and Paracoccidioidomycosis); Chapter 9: Use of Voriconazole As Antifungal Prophylaxis and Empirical Therapy During Chemotherapy in Immunodepressed Patients and in Solid Organ Transplantation; Chapter 10: Use of Voriconazole in Pediatric Patients with Cancer
- PART IIIChapter 11: Voriconazole: Contraindications, Warnings and Precautions, Adverse Reactions; Chapter 12: Drug Interactions with Voriconazole; Chapter 13: Drug Resistance Against Voriconazole; Chapter 14: Voriconazole Toxicology; Chapter 15: Therapeutic Drug Monitoring of Voriconazole; Chapter 16: Pharmacoeconomics of Voriconazole; Index
- Notes:
- Description based upon print version of record.
- Includes bibliographical references at the end of each chapters and index.
- Description based on print version record.
- ISBN:
- 1-63463-940-5
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