My Account Log in

1 option

Uncertain precision : managing health care with personalized technologies / Reed E. Pyeritz.

Oxford Medicine Online Available online

View online
Format:
Book
Author/Creator:
Pyeritz, Reed E., author.
Contributor:
Oxford Academic Medicine
Series:
Oxford medicine online.
Oxford medicine online
Language:
English
Subjects (All):
Medical care--Technological innovations.
Medical care.
Precision medicine.
Precision Medicine.
Medical Subjects:
Precision Medicine.
Physical Description:
1 online resource : illustrations.
Place of Publication:
New York, NY : Oxford University Press, [2026]
Contents:
Cover
Half Title
Title Page
Copyright Page
Dedication
Table of Contents
Abbreviations
Acknowledgments
Prologue
1 Introduction
2 Personalized Medicine Cannot Always Be Precise, But Precision Medicine Must Always Be Personalized
Personal Encounters With Health Care
Formalizing Personalized Medicine
Personalized and Precision Medicine: Distinct, Or Two Sides of the Same Coin?
The Historic Precedents of Precision Medicine
Primum Non Nocera
Early Promises, Successes, and Stumbles of Precision Medicine
Biomarkers and Precision Medicine Today
Precision Medicine Must Always Be Personalized
Precision Health Care at a Population Level
Conclusions
3 Uncertainty Is a Fact of Life
The Scope of Uncertainty: An Inescapable Attribute of Life
Uncertainty in Science and the Science of Uncertainty
How Do We Cope With Uncertainty?
Statistics Provide Legitimacy, But Not Certainty, to Data
4 Uncertainty Pervades All Health Care
Two Centuries of Uncertainty
Uncertainty in the Clinic and Clinical Uncertainty
Diagnosis-Creep
What Is Normal?
Quantifying Uncertainty
Regrettable Sources of Uncertainty
Intersection of Science and Medicine Emphasizes That Enormous Ignorance Remains
Exploring Your Own Health
Coping With Uncertainty By Embracing It
5 Artificial Intelligence: Origins, Applications, and Challenges
In the Beginning . . .
ChatGPT and Beyond
Rate-Limiting Factors
6 How Artificial Intelligence Enhances Health Care
When an Artificial Intelligence Algorithm Makes Your Health Care Decisions
Clinical Decision Making
AI and Interpreting Images
AI and Diagnosis
AI and Treatment
AI and Counseling Patients
AI and Clinical Guidelines
AI and Understanding Variability
AI and Clinical Trials
AI and Public Health
AI and Sources of Medical Information for Patients
AI and Publishing
Coda
7 Our -Omics
How-Omes Define Our World
Genomics
Epigenomics
Exposomics
Metabolomics
Microbiomics
Pharmacogenomics
Personomics
Integration of -Omics
Artificial Intelligence and -Omics
8 Our Genomes
The Language of Life
The Organization of Genetic Information
The Human Genome Project
The Problem With the Gene Pool Is That There Is No Lifeguard
9 Exploring Our Genes
Genetic Individuality
Family History
Genealogy
Genomics Is a Scalable Commodity
Who Has Access to Your Genetic Data, and How Can It Be (Mis)Used?
Why Perform Genetic Analysis?
Searching for Causative Genetic Variants
Incidental Findings
Some Ironies of Genetic Analysis
One Genetic Test May Be Insufficient
Complexities Testing for the Risk of Common Conditions
DNA Testing for Cancer: Promises of Certainty But Options Plagued With Uncertainties
Potential Benefits of Genetic Testing Require Accepting Anxiety
Notes:
Includes bibliographical references and index.
Electronic reproduction. Oxford Available via World Wide Web.
Description based on online resource and publisher information; title from PDF title page (viewed on November 17, 2025).
Other Format:
Print version :
ISBN:
9780197796320
019779632X
9780197796306
0197796303
Publisher Number:
90103658793
CIPO000316891
Access Restriction:
Restricted for use by site license.

The Penn Libraries is committed to describing library materials using current, accurate, and responsible language. If you discover outdated or inaccurate language, please fill out this feedback form to report it and suggest alternative language.

My Account

Shelf Request an item Bookmarks Fines and fees Settings

Guides

Using the Library Catalog Using Articles+ Library Account