Nano-organization of the Synapse : From Structure to Function / edited by Ege Kavalali.

Format:

Book

Contributor:

Kavalali, Ege., Editor.

Series:

Advances in Neurobiology, 2190-5223 ; 48

Language:

English

Subjects (All):

Neurosciences.

Neurophysiology.

Neurons.

Neuroanatomy.

Neuroscience.

Cellular Neuroscience.

Local Subjects:

Neuroscience.

Cellular Neuroscience.

Neuroanatomy.

Physical Description:

1 online resource (IX, 356 p. 53 illus., 52 illus. in color.)

Edition:

1st ed. 2026.

Place of Publication:

Cham : Springer Nature Switzerland : Imprint: Springer, 2026.

Summary:

This open-access book presents recent advances in our understanding of the nano-structure of synaptic junctions in terms of their organization, mechanisms of assembly, and role in neuronal signaling as well as plasticity. Traditionally, a single synapse was assumed to have a homogeneous organization of molecular components both at the active zone and postsynaptically. Recent advances in imaging tools and the further elucidation of the physiological significance of distinct forms of release have challenged this notion. This is a timely book that will richly contribute to the ongoing efforts to develop this novel perspective into the study of the nervous system.

Contents:

Nano-organization of the synapse: An Overview

Structural Biology of Neurotransmitter Release Machinery

Vesicle pools: Composition, physical locations

Organization of the active zone

Synaptic cell adhesion

Synaptic cell adhesion, a structural perspective

Postsynaptic receptors and scaffolds

Functional nano-segregation of distinct forms of neurotransmission

Optical approaches to dissect nano-structure

Cryo-EM tomography

Roles of Glia in Synapse Nano-Organization.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-032-12594-4

9783032125941

OCLC:

1569885000