Low-Dimensional Materials, Systems, and Applications, Volume 2 : Principles, Methods, and Approaches in Biomedicine and Bioengineering.

Format:

Book

Author/Creator:

Chakraborty, Purushottam.

Contributor:

Mohanta, D. (Dambarudhar)

Series:

Woodhead Publishing Series in Electronic and Optical Materials Series

Language:

English

Physical Description:

1 online resource (606 pages)

Edition:

1st ed.

Place of Publication:

Chantilly : Elsevier Science & Technology, 2025.

Summary:

Low-Dimensional Materials, Systems, and Applications, Volume 2: Principles, Methods, and Approaches in Biomedicine and Bioengineering showcases the complexities and uniqueness of low-dimensional materials and highlights the most recent discoveries in the fields of biomedicine and bioengineering.

Contents:

Front Cover

Low-Dimensional Materials, Systems, and Applications

Copyright Page

Contents

List of contributors

About the editors

Preface

1 Green synthesis of multi-dimensional carbon nanocomposites for energy and biotechnology applications

1.1 Introduction

1.2 Controllable fabrication of ion-induced nanostructures and their extension to multi-dimensional nanostructures

1.3 Composition and crystallinity control of ion-induced multi-dimensional nanostructures

1.4 Energy-related applications of ion-induced multi-dimensional nanostructures

1.5 Bio-related applications of ion-induced multi-dimensional nanostructures

1.6 Conclusion

Acknowledgments

References

2 Boron-based optical probes for biological applications

2.1 Chemistry of boron

2.2 Hydrogen peroxide-responsive organoborons

2.2.1 Organoboron chemosensors for H2O2 imaging

2.3 Aza-BODIPY

2.3.1 General synthetic strategies

2.3.2 Fluorescent probes

2.3.3 Fluorescent probes for metal ions

2.3.4 Fluorescent probes for anion

2.3.5 Fluorescent probe for pH

2.3.6 Fluorescent probes for biological factors

2.3.7 Photoacoustic imaging technology

2.3.8 Photoacoustic imaging for metal ion detection

2.3.9 Photoacoustic imaging for detection of reactive oxygen and nitrogen species

2.3.10 Photoacoustic imaging for hypoxia detection

2.4 Boron-dipyrromethene

2.4.1 Synthesis of boron-dipyrromethene

2.4.2 Boron-dipyrromethene fluorescent probes for imaging

2.4.2.1 Ultrafast optical spectroscopy of novel boron-based fluorescent probes for sensing reactive oxygen species for cancer diagnosis and treatment

2.5 Conclusion

3 Charge pump circuits for biomedical and IoT applications in nanoelectronics

3.1 Introduction

3.2 Metal oxide semiconductor-based device background

3.3 Charge pump basics.

3.4 Charge pump types

3.4.1 Dickson charge pump

3.4.2 Bootstrap charge pump

3.4.3 Fibonacci charge pump

3.4.4 Double charge pump

3.5 Charge pump applications

3.5.1 Micro power energy harvesting

3.5.2 Biomedical applications

3.5.3 Development opportunities

3.6 Summary

4 Nanosystems as contrast agents for high-performance biomedical imaging

4.1 Introduction

4.2 Evolution of molecular imaging

4.3 Imaging techniques

4.3.1 Magnetic resonance imaging

4.3.2 Fluorescence imaging

4.4 Imaging probe

4.4.1 Magnetic resonance imaging probe

4.4.1.1 T1 magnetic resonance imaging contrast agents

4.4.1.2 T2 magnetic resonance imaging contrast agents

4.4.2 Fluorescence imaging probe

4.4.3 Multimodal nanoprobes

4.5 Conclusion

Further Reading

5 Surface-enhanced Raman spectroscopy of low-dimensional carbon-based materials for chemical and biological sensing applications

5.1 Introduction

5.1.1 Enhancement mechanism

5.1.2 Electromagnetic enhancement mechanism in SERS

5.1.3 Chemical enhancement

5.2 Carbon-based SERS substrate

5.2.1 Carbon nanotubes

5.2.2 Graphene

5.2.2.1 Graphene/graphene oxide-metal hybrid substrates

5.2.3 Carbon dot-based SERS substrate

5.2.4 Three-dimensional carbon-based SERS substrate

5.3 Conclusions and future outlook

6 Advances in low-dimensional graphene and conductive polymers for tissue engineering and regenerative applications

6.1 Introduction

6.2 Properties of graphene and its chemical derivatives

6.2.1 Chemical properties of graphene and its derivatives

6.2.2 Graphene oxide and reduced graphene oxide

6.2.3 Structural variants of graphene

6.3 Functionalization of graphene-based nanomaterials

6.3.1 Methods for functionalizing graphene and its derivatives.

6.3.1.1 Covalent functionalization

6.3.2 Noncovalent functionalization

6.4 Ionic versus electron conductivity of graphene

6.5 Properties of graphene and its chemical derivatives: suitability as a bioactive material

6.6 Applications of graphene in tissue engineering and regenerative medicine

6.6.1 Bone tissue engineering and regeneration

6.6.2 Cardiac tissue engineering and regeneration

6.6.3 Neural tissue engineering and regeneration

6.6.3.1 Neuronal differentiation of stem cells on graphene

6.6.3.2 Neuronal activity on graphene

6.6.3.3 Graphene constructs for neural regeneration: 2D and 3D

6.6.4 Skeletal muscle tissue engineering and regeneration

6.6.5 Skin/adipose tissue engineering and regeneration

6.7 Biocompatibility and biotoxicity of graphene

6.7.1 Biocompatibility of graphene

6.7.2 Biotoxicity of graphene

6.8 Use of conducting polymers in tissue engineering and regeneration

6.8.1 Neural prosthetics

6.8.2 Muscle prosthetics

6.8.3 Conducting polymers as an interface in bioprosthetics

6.8.4 Electrical stimulation of tissues

6.8.5 Drug delivery systems

6.8.6 Scaffold materials in tissue engineering

6.8.7 Biodegradable conducting polymers for temporary implants

6.9 Biomedical materials

6.10 Bio-instructive materials

6.10.1 Applications of bio-instructive materials

6.10.1.1 Bone tissue engineering

6.10.1.2 Cartilage tissue engineering

6.10.1.3 Cardiac tissue engineering

6.10.1.4 Neural tissue engineering

6.10.1.5 Soft tissue engineering (skin, muscle, and liver)

6.11 Emerging technologies in tissue engineering and regeneration

6.11.1 Printing technologies: 3D, 4D, and 5D

6.11.1.1 3D printing

6.11.1.2 4D printing

6.11.2 Shape-memory polymers in 4D printing

6.11.3 Applications in biomedical devices.

6.11.4 Future directions in 4D bioprinting

6.11.5 5D printing

6.11.6 6D printing

6.12 Computational modeling in tissue engineering and regeneration

6.12.1 Finite element analysis in tissue engineering and regeneration

6.12.1.1 Structural analysis using finite element analysis

6.12.1.2 Fatigue and durability testing using finite element analysis

6.12.2 Computational fluid dynamics in tissue engineering and regeneration

6.12.2.1 Applications of computational fluid dynamics in tissue engineering

6.12.2.2 Spatial and periodic discretization in computational fluid dynamics

6.12.2.3 Incorporating cell growth in computational fluid dynamics simulations

6.12.2.4 Computational fluid dynamics model verification

6.13 The role of artificial intelligence in tissue engineering and regeneration

6.13.1 Artificial intelligence-aided design and predictive modeling in tissue engineering

6.13.1.1 Predictive modeling and simulation

6.13.1.2 Artificial intelligence-driven optimization of biomaterial properties

6.13.2 Artificial intelligence-based design of scaffolds and bioinks for 3D printing

6.13.3 Machine learning for image analysis

6.13.4 Artificial intelligence in scaffold design, cell optimization, and therapeutics development

6.14 Challenges and future directions

6.14.1 Material limitations and biocompatibility

6.14.2 Scaffold fabrication and tissue integration

6.14.3 Optimization of bioinks and biomaterial properties

6.14.4 Mechanical and electrical stimulation

6.14.5 Artificial intelligence and computational modeling

6.14.6 Regulatory and ethical considerations

6.14.7 Scaling up and commercialization

6.14.8 Safety, biocompatibility, and smart materials

6.14.9 Ethical and societal implications of organ regeneration

6.15 Conclusion

References.

7 Low-dimensional materials for advanced pharmaceutical applications

7.1 Introduction

7.2 Classification of low-dimensional materials

7.3 Role of low-dimensional materials in pharmaceutical applications

7.4 LDMs for targeted drug delivery

7.5 Low-dimensional materials for therapeutics

7.6 Low-dimensional materials for diagnostics and detection

7.7 Conclusion and future prospects

8 Nanozymes: harnessing the tiny titans against bacterial infections, oxidative stress, and cancer

8.1 Introduction

8.2 Targeted antibacterial therapy

8.3 Nanozymes to address oxidative stress

8.4 Harnessing nanozymes to address cancer

8.5 Challenges and future directions in nanozyme-based therapies

8.5.1 Expanding enzyme mimicry

8.5.2 Developing targeted nanozyme systems

8.5.3 Enhancing biocompatibility and safety

8.5.4 Understanding influence of external factors/stimuli on enzyme activity

8.5.5 Exploring new disease targets

8.6 Concluding remarks

9 Exploring protein based nanoparticles for drug delivery: materials, methods and applications

9.1 Introduction

9.2 Classification of proteins

9.3 Advantages and disadvantages of the protein-based nanoparticles

9.4 Proteins commonly utilized in protein nanoparticle production

9.4.1 Fibroin

9.4.2 Gelatin

9.4.3 Elastin

9.4.4 Zein

9.4.5 Gliadin

9.4.6 Lectin

9.4.7 Soy protein

9.4.8 Collagen

9.4.9 Albumins

9.4.10 Globulins

9.4.11 Casein

9.5 Techniques for creating protein nanoparticles

9.5.1 Chemical processes

9.5.1.1 Emulsion extraction

9.5.1.2 Complex coacervation method

9.5.2 Physical methods

9.5.2.1 Nano spray drying

9.5.2.2 Electrospray technique

9.5.3 Self-assembly

9.5.3.1 Self-assembly of protein micelles

9.5.3.2 Desolvation.

9.6 Conclusion and prospect.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

0-443-44594-X

9780443445941

OCLC:

1547930390