Copper in Biology : Molecular Structures, Cellular Processes and Living Systems.

Format:

Book

Author/Creator:

Furukawa, Yoshiaki.

Contributor:

Fujieda, Nobutaka.

Series:

Coordination Chemistry Perspectives Series

Coordination Chemistry Perspectives Series ; v.Volume 3

Language:

English

Subjects (All):

Copper proteins.

Copper.

Physical Description:

1 online resource (375 pages)

Edition:

1st ed.

Place of Publication:

Cambridge : Royal Society of Chemistry, The, 2025.

Summary:

The contributors review the biological significance of copper from different perspectives, ranging from bio-inspired catalysts, as a mechanism of copper proteins, to pathological roles in diseases.

Contents:

Cover

Title

Copyright

Preface

Contents

Section I: Recent Progress on the Structures and Functions of Copper-containing Proteins

Chapter 1 Structure and Function of Cu/Zn-superoxide Dismutase

1.1 Introduction

1.2 Structural Features of Cu/Zn-SOD

1.2.1 Metal Binding in Cu/Zn-SOD

1.2.2 Metal Acquisition of Cu/Zn-SOD

1.2.3 Structural Features Enabling the Catalytic Activity of Cu/Zn-SOD

1.2.4 Distinct Structural Features of Prokaryotic and Eukaryotic Cu/Zn-SOD

1.2.5 Other Structural Variations in Cu/Zn-SOD

1.3 Functional Relevance of Cu/Zn-SOD

1.3.1 Phenotypic Consequences of Cu/Zn-SOD Deficiency in Organisms

1.3.2 Pathological Implications of Cu/Zn-SOD Variants in Humans

1.3.3 Physiological Roles of Cu/Zn-SOD Beyond Superoxide Dismutation

1.4 Perspective

References

Chapter 2 Structure and Function of Dinuclear Copper Tyrosinase

2.1 Introduction

2.2 Auxiliary Domains and Subunits

2.3 Catalytic Core Domains

2.3.1 Substrate Binding Modes

2.3.2 Base as a Proton Accepter from a Phenol Substrate

2.3.3 Flexibility of the Copper Centre

2.4 Perspective

Abbreviations

Acknowledgements Generated by AI.

Notes:

Description based on publisher supplied metadata and other sources.

Part of the metadata in this record was created by AI, based on the text of the resource.

ISBN:

1-83767-795-6

1-83767-796-4

OCLC:

1531590945