Zinc in Biology : Molecular Structures, Cellular Processes and Living Systems.

Format:

Book

Author/Creator:

Yasui, Hiroyuki.

Contributor:

Kambe, Taiho.

Series:

Coordination Chemistry Perspectives Series

Coordination Chemistry Perspectives Series ; v.Volume 2

Language:

English

Subjects (All):

Zinc.

Homeostasis.

Physical Description:

1 online resource (328 pages)

Edition:

1st ed.

Place of Publication:

Cambridge : Royal Society of Chemistry, The, 2025.

Summary:

Zinc plays a pivotal role in living systems and it is involved in a variety of physiological events in cells. Recent research is explored along with the roles of zinc in health and disease.

Contents:

Cover

Title

Copyright

Preface

Contents

Section I: Recent Progress in Zinc Complexes and Zinc Probes for Imaging

Chapter 1 Quantitative Imaging of Labile Zinc in Intracellular Organelles Using Fluorescent Probes

1.1 Introduction

1.2 Important Properties of Fluorescent Probes for Quantitatively Imaging Labile Zn2+ in Living Cellular Compartments

1.3 Quantitative Imaging Using Fluorescent Probes

1.3.1 Small-molecule (SM) Probes

1.3.2 Fluorescent Protein (FP)-based Probes

1.3.3 Small Molecule–Protein Hybrid Fluorescent Probes

1.4 Quantitative Imaging of Intracellular Zn2+ Using Hybrid Fluorescent Probes

1.4.1 Design and Properties of ZnDA Probes

1.4.2 Subcellular Targeting of ZnDA Probes and Labile Zn2+ Quantification Using Colocalization Ratiometry

1.4.3 Organelle-level Labile Zn2+ Mapping Using ZnDA Probes

1.5 Conclusions and Future Perspectives

Acknowledgements

References

Chapter 2 Zinc Conditional Proteomics Using Zinc-responsive Protein Labelling Reagent and Recent Examples of Expansion to Other Biometals

2.1 Introduction

2.2 Zinc Conditional Proteomics

2.2.1 Development of Zn2+-responsive Protein Labelling Reagent

2.2.2 AIZin-2-mediated Profiling of Dynamic Changes in Proteins in the Zn2+-rich Region upon NO Stimulation

2.2.3 Detection of Mobile Zn2+ Levels in Plants

2.3 Iron Conditional Proteomics

2.4 Copper Conditional Proteomics

2.4.1 AI-based Cu+/Cu2+-responsive Probes

2.4.2 Quinone Methide-based Cu+-selective Probe Generated by AI.

Notes:

Description based on publisher supplied metadata and other sources.

Part of the metadata in this record was created by AI, based on the text of the resource.

ISBN:

1-83767-658-5

OCLC:

1524994647