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VIDEO 302-2B: Pharmacologic modulation of mutant CFTR / Dan Longo, Eric J. Sorscher.
- Format:
- Video
- Author/Creator:
- Longo, Dan, author.
- Sorscher, Eric J., author.
- Series:
- McGraw-Hill's AccessMedicine.
- Language:
- English
- Subjects (All):
- Cystic fibrosis.
- Mucociliary system--Physiology.
- Mucociliary system.
- Physical Description:
- 1 online resource (1 video file, approximately 22 secs.) : digital, .flv file, sound.
- Contained In:
- Harrison's Principles of Internal Medicine 22e. New York, N.Y. : McGraw-Hill Education, 2025
- Place of Publication:
- New York, N.Y. : McGraw-Hill Education LLC., 2025.
- Language Note:
- In English.
- System Details:
- digital
- video file MPEG-4 Flash
- Notes:
- (B) describes CFTR encoding a maturational processing (protein biogenesis, class II) defect. The mutant protein is misfolded, fails to traffic to the cell surface, and is degraded by the proteasome. Binding of corrector molecules (red spheres) i
- Title from title frames.
- Originally produced by Dan Longo in 2025.
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