Ethics and Regulation of Clinical Research / Robert F. Drinan.

Format:

Book

Author/Creator:

Drinan, Robert F., Author.

Language:

English

Physical Description:

1 online resource

Place of Publication:

New Haven, CT : Yale University Press, [2011]

Language Note:

In English.

Summary:

The use of human subjects in medical and scientific research has given rise to troubling ethical questions. How should human subjects be selected for experiments? What should they be told about the research in which they are involved? How can their privacy be protected? When is it permissible to deceive them? How do we deal with subjects such as children, fetuses, and the mentally infirm, for whom informed consent is impossible? In this book, Dr. Robert J. Levine reviews federal regulations, ethical analysis, and case studies in an attempt to answer these questions. His book is an essential reference for everyone-members of institutional review boards, scientists, philosophers, lawyers-addressing the ethical issues involved."[Levine's] experience as a clinician, IRB chairman, writer and editor of a journal devoted exclusively to issues faced by IRBS makes him uniquely qualified to bring together the legal, ethical, and practical dimensions. . . [The book] is sophisticated but readable. . . [and] should be on every IRB administrator's desk and in every medical ethics library."-Norman Fost, M.D., The New England Journal of Medicine"Levine. . . is one of the foremost historians of contemporary clinical science. . . . His book is at once a guide to primary sources for the history of clinical research in the late twentieth century and a pioneering secondary source about that history."-Daniel M. Fox, Bulletin of the History of Medicine"You will be charmed by the [book's] elegance and lucidity and. . . persuaded of its relevance to doctors in any country."-Alex Paton, British Medical Journal"Should be of wide interest to those keen to see advances in medical research brought into general medical practice."-Gilbert Omenn, Issues in Science and Technology

Contents:

Frontmatter

Contents

Preface To The First Edition

Preface To The Second Edition

Acknowledgments

Chapter 1. Basic Concepts And Definitions

Chapter 2. Ethical Norms And Procedures

Chapter 3. Balance Of Harms And Benefits

Chapter 4. Selection Of Subjects

Chapter 5. Informed Consent

Chapter 6. Compensation For Research-Induced Injury

Chapter 7. Privacy And Confidentiality

Chapter 8. Randomized Clinical Trials

Chapter 9. Deception

Chapter 10. Children

Chapter 11. Those Institutionalized As Mentally Infirm

Chapter 12. Prisoners

Chapter 13. The Fetus And The Embryo

Chapter 14. The Institutional Review Board

References

Appendix 1: Department Of Health And Human Services Rules And Regulations

Appendix 2: Food And Drug Administration Rules And Regulations

Appendix 3: The Nuremberg Code

Appendix 4: World Medical Association Declaration Of Helsinki

Appendix 5: Leo Szilard's Ten Commandments

Index

Notes:

Description based on online resource; title from PDF title page (publisher's Web site, viewed 24. Apr 2020)

ISBN:

9780300163490

0300163495

OCLC:

1024040519