Peptide Antibiotics Biosynthesis and Functions : Enzymatic Formation of Bioactive Peptidesand Related Compounds / editors, Horst Kleinkauf and Hans von Döhren.

Format:

Book

Contributor:

Kleinkauf, Horst, 1930- editor.

Döhren, Hans von, editor.

Language:

English

Subjects (All):

Microbiological synthesis.

Physical Description:

1 online resource (XI, 479 p.) : Num. figs. and tables

Edition:

First edition.

Place of Publication:

Berlin, Germany : Walter de Gruyter, [1982]

Language Note:

In English.

Summary:

No detailed description available for "Peptide Antibiotics Biosynthesis and Functions".

Contents:

Frontmatter

Preface

Foreword

Contents

I. Introduction

A Survey of Enzymatic Peptide Formation

On Biosynthesis of the Cyclic Antibiotics Gramicidin S and Tyrocidine, and of Linear Gramicidin

II. Pathways and Genetics

Chemistry and Biosynthesis of the Poly (y-D-Glutamyl) Capsule in Bacillus licheniformis

Recent Developments with Cell free Extracts on the Enzymic Biosynthesis of Penicillins and Cephalosporins

Accumulation of <5-(L-a-Aminoadipyl)-L-Cysteinyl-D-Valine Derivatives by Mutants of Cephalosporium acremonium

Genetic Studies on the Biosynthesis of Actinomycin

Role of Peptides from Mycobacillin-Synthesizing System in the Biosynthesis of Mycobacillin

III. Fermentations and Peptide Production

Environmental Influences on the Dynamics of the Gramicidin S Fermentation

Production of Gramicidin S-Synthetase from Bacillus brevis ATCC 9999 by Batch Fermentation

Studies on the Gramicidin S-Synthetase Production in Bacillus brevis ATCC 9999 in C- and P-Limited Chemostat Cultures

On the Role of L-Leucine in the Control of Bacitracin Formation by Bacillus licheniformis

Current Research in Ergot Peptide Synthesis by Claviceps purpurea

Applications of Multienzyme Systems in the Production of Peptide Antibiotics

IV. Enzyme Systems

The Fidelity of Gramicidin S-Synthetase with Particular Reference to the Amino Acids Cyclohexylalanine and Phenylalanine

Some Characteristics of Gramicidin S-Synthetase Obtained from Mutants of Bacillus brevis which could not form DPhenylalanyl- L-Prolyl Diketo-Piperazine

Kinetics of Amino Acid Activation in Gramicidin S Synthesis

The Temperature Dependence of the Partial Processes Involved in the Biosynthesis of Gramicidin S

Further Characterization of Multienzyme Fragments of Gramicidin S Synthetase obtained from Gramicidin S Nonproducer Mutants

Limited Proteolysis: Studies on the Multienzyme GS2 of Gramicidin S-Synthetase

Tryptic Cleavage of the Heavy Enzyme of Gramicidin SSynthetase

Use of Affinity Chromatography in Purification of Gramicidin S-Synthetases

A Survey on the Use of Affinity Chromatography for Studying the Mechanism of Gramicidin S Formation

Other Synthetases

Enniatin-Synthetase: Studies on the Activation of Residues Involved in Enniatin Synthesis

Biosynthesis of Antibiotic Peptides Polymyxin E and Gramicidin A

Component I Protein of Bacitracin Synthetase: A Multifunctional Protein

Bacitracin Synthetase Subenzymes and Tail Peptide Formation in Bacitracin

Bacitracin Synthetase. Tryptic Cleavage of Enzymes B and C

Edeine Synthetase: Evidence for Bidirectional Synthesis of Edeines

Biosynthesis of Leupeptin

Biosynthesis of Carnosine and Related Peptides

Inhibition of Carnosine Synthetase by Spermidine

Corynebacterium species Folylpoly-y-Glutamate Synthetase

Discussion Peptide Synthetases - Problems and Properties Summary of a round-table discussion held on Sept. 5th, 1980

V. Possible Functions of Peptide Antibiotics in their Producer Organisms

A Survey of Possible Functions of Peptide Antibiotics in the Producer Organisms

Tyrocidine Induced Sporulation of Bacillus brevis in a Medium Lacking A Nitrogen Source

Studies on the Role of Gramicidin S in the Life Cycle of its Producer Bacillus brevis ATCC 9999

Investigations on the Function of Amatoxins in Amanita Species: A Case for Amatoxins as Potential Regulators of Transcription

Structural Requirements for the Biological Activity of Polymyxin B

Gramicidin S - Fragments Generated by Mild Acid Hydrolysis of the Antibiotic

Relevance of the Association of Polymyxin Biosynthetic Complex with Membrane DNA During Growth and Sporulation of B. polymyxa

Author Index

Subject Index

Notes:

Description based on online resource; title from PDF title page (publisher's Web site, viewed 28. Mrz 2023)

Description based on print version record.

ISBN:

3-11-083783-8

OCLC:

1374540511