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Breast Cancer Immunotherapy / edited by Marcus Schmidt, Rita Nanda.

Springer Nature - Springer Medicine (R0) eBooks 2025 English International Available online

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Format:
Book
Author/Creator:
Schmidt, Marcus.
Contributor:
Nanda, Rita.
Series:
Cancer Immunotherapy, 2662-8392 ; 3
Language:
English
Subjects (All):
Immunotherapy.
Internal medicine.
Immunology.
Gynecology.
Internal Medicine.
Local Subjects:
Immunotherapy.
Internal Medicine.
Immunology.
Gynecology.
Physical Description:
1 online resource (374 pages)
Edition:
1st ed. 2025.
Place of Publication:
Cham : Springer Nature Switzerland : Imprint: Springer, 2025.
Summary:
This comprehensive book presents the most up-to-date and innovative information on the immunotherapy of breast cancer. The book opens by providing an introduction to mechanisms of the immune system in cancer, including the principles of immunoediting and the cancer-immunity cycle. After discussion of the prognostic and predictive roles of the immune system in breast cancer, attention is turned to successful therapeutic strategies. The use of monoclonal antibodies is thoroughly described, and a particular focus of the book is the use of checkpoint inhibitors to strengthen the immune system by releasing its brakes, this being an area of growing importance. In addition, novel vaccination strategies in breast cancer and early treatment concepts using chimeric antigen receptor (CAR) T cells are covered in depth. The book concludes by examining future prospects in the field. Written by international experts in the topics that they address, Breast Cancer Immunotherapy will be a valuable update for researchers and clinical practitioners alike.
Contents:
Part I: Immunity and Cancer
The Functional Cancer Immunity Cycle
Rationale for Immunotherapy for Breast Cancer
Tumor-Infiltrating Lymphocytes as a Prognostic and Predictive Marker in Breast Cancer
Part II: Therapeutic Interventions for Breast Cancer
Therapeutic Interventions for Breast Cancer: Advanced Breast Cancer
Immunotherapy in Early Triple-Negative Breast Cancer
Part III: Vaccines
Peptide Vaccines in Breast Cancer
mRNA Vaccination for Breast Cancer
Part IV: Emerging Therapeutic Strategies
Radiation and Immunotherapy in Breast Cancer
The Clinical Development of Immune Checkpoint Inhibitors in Combination with Targeted Therapy in Breast Cancer
Targeting the STING Pathway in Breast Cancer
Immunotherapy Combinations and Dual Checkpoint Blockade
CAR T Cell Strategies for Metastatic Breast Cancer
Part V: Emerging Biomarkers of Response to Immunotherapy
Tumor Characteristics
Host Characteristics in Breast Cancer.
Notes:
Description based on publisher supplied metadata and other sources.
ISBN:
3-032-06908-4
9783032069085
OCLC:
1543045248

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