Nanodots for Cancer Diagnosis and Treatment.

Format:

Book

Author/Creator:

Prajapati, Bhupendra G.

Contributor:

Kapoor, Devesh U.

Ali, Nemat.

Language:

English

Subjects (All):

Nanotechnology.

Drug delivery systems.

Physical Description:

1 online resource (452 pages)

Edition:

1st ed.

Place of Publication:

Chantilly : Elsevier Science & Technology, 2025.

Summary:

Nanodots for Cancer Diagnosis and Treatment presents a pioneering exploration of nano-scale drug delivery systems that promise to revolutionize cancer care.This book, with insights from global scientific collaborations, delves into various nanodots employed in cancer diagnosis and treatment.

Contents:

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Front Matter

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Titlepage

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Copyright

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Dedication

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Contents

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Contributors

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Editor Bio

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Preface

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Acknowledgments

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Chapter 1 Introduction to nanotechnology in cancer care

1.1 Basics of nanotechnology in cancer

1.2 Cancer biology and the need for nanotechnology

1.2.1 The role of nanotechnology in overcoming these challenges

1.3 Types of nanomaterials for cancer diagnosis and treatment

1.3.1 Quantum dots

1.3.2 Gold nanoparticles

1.3.3 Liposomes and micelles

1.3.4 Dendrimers

1.3.5 Magnetic nanoparticles

1.4 Mechanisms of nanotechnology in cancer diagnosis

1.4.1 Targeted imaging using nanoprobes

1.4.2 Early detection techniques with nanoparticles

1.4.3 Role of nanotechnology in precision imaging

1.5 Nanotechnology for cancer treatment

1.5.1 Targeted drug delivery systems

1.5.2 Nanoparticle-based chemotherapy

1.5.3 Hyperthermia therapy using nanomaterials

1.5.4 Gene therapy with nanovectors

1.5.5 Radiation therapy enhancement using nanomaterials

1.6 Advantages of nanotechnology in cancer care

1.7 Current challenges and limitations

1.8 Future directions of nanotechnology in cancer

1.9 Conclusion

References

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Chapter 2 Fundamentals of nanodots: Synthesis and characterization

2.1 Introduction to nanodots

2.1.1 Definition and overview

2.1.2 Historical development of nanodots

2.1.3 Importance in nanotechnology and biomedical applications

2.2 Classification of nanodots

2.2.1 Types of nanodots: Quantum dots, carbon dots, and others

2.2.2 Physical and chemical properties

2.2.3 Comparison with other nanomaterials.

2.3 Synthesis of nanodots

2.3.1 Chemical synthesis methods

2.3.2 Biological synthesis methods

2.4 Green synthesis approaches

2.4.1 Synthesis based on plant extracts

2.4.2 Microbial synthesis

2.4.3 Carbon sources derived from biomass

2.4.4 Enzyme-catalyzed synthesis

2.4.5 Synthesis based on natural polymers

2.4.6 Hydrothermal or microwave-assisted eco-friendly synthesis

2.4.7 Synthesis mediated by algae

2.4.8 Challenges in nanodots synthesis

2.5 Characterization of nanodots

2.5.1 Structural characterization

2.5.2 Optical properties

2.5.3 Surface characterization

2.5.4 Magnetic and electrical properties

2.6 Nanodots in cancer diagnosis

2.6.1 Nanodots as imaging agents

2.6.2 Nanodots for early cancer detection

2.6.3 Targeted imaging using functionalized nanodots

2.7 Nanodots in cancer treatment

2.7.1 Nanodots in photothermal therapy

2.7.2 Nanodots in photodynamic therapy

2.7.3 Drug delivery system using nanodots

2.7.4 Synergistic cancer therapies involving nanodots

2.8 Toxicity and biocompatibility of nanodots

2.8.1 In vitro toxicity studies

2.8.2 In vivo toxicity and biodistribution

2.8.3 Strategies to reduce toxicity

2.9 Regulatory and ethical considerations

2.9.1 Current regulatory guidelines for nanodots

2.9.2 Ethical issues in nanodots application

2.9.3 Future directions in regulation

2.10 Future prospects of nanodots in oncology

2.10.1 Latest developments in nanodot research

2.10.2 Opportunities and possible difficulties

2.10.3 Vision for the next decade

2.11 Conclusion

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Chapter 3 Nanodots for cancer imaging: Techniques and applications

3.1 Introduction

3.1.1 Overview of cancer

3.1.2 Introduction to nanodots

3.1.3 Introduction to imaging techniques

3.2 Nanodots for cancer diagnosis.

3.2.1 Carbon-based quantum dots

3.2.2 Semiconductor quantum dots

3.2.3 Quantum dots for In Vitro tumor imaging

3.2.4 Quantum dots for In Vivo tumor imaging

3.3 Targeted bioimaging

3.3.1 Uptake accumulation

3.3.2 Charge or pH

3.4 Targeting biomarker

3.5 Theranostics

3.5.1 Targeting drug delivery

3.5.2 Photothermal therapy

3.5.3 Photodynamic Therapy

3.6 Future challenges and opportunities

3.7 Conclusion

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Chapter 4 Targeted drug delivery systems using nanodots

4.1 Introduction

4.2 Application of nanodots for diagnosis and treatment of breast cancer

4.3 Application of nanodots for diagnosis and treatment of lung cancer

4.4 Application of nanodots for diagnosis and treatment of liver cancer

4.5 Application of nanodots for diagnosis and treatment of pancreatic cancer

4.6 Application of nanodots for diagnosis and treatment of skin cancer

4.7 Application of nanodots for diagnosis and treatment of colon cancer

4.8 Future perspective and conclusion

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Chapter 5 Role of quantum dots in cancer diagnosis and treatment

5.1 Introduction

5.2 Unique properties of quantum dots

5.3 Quantum dots in cancer diagnosis

5.4 Quantum dots in cancer treatment

5.5 Challenges and limitations

5.6 Future directions

5.7 Conclusion

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Chapter 6 Role of gold nanodots in cancer diagnosis and treatment

6.1 Introduction

6.2 Synthesis and functionalization of gold nanodots

6.2.1 Physical synthesis

6.2.2 Chemical synthesis

6.2.3 Green/biological synthesis

6.3 Surface modification and targeting strategies

6.4 Gold nanodots in cancer diagnosis

6.5 Gold nanodots in cancer treatment

6.6 Toxicity and biocompatibility of gold nanodots

6.6.1 Toxicity.

6.6.2 Biocompatibility

6.7 Conclusion

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Chapter 7 Role of graphene nanodots cancer in diagnosis and treatment

7.1 Introduction to graphene nanodots

7.1.1 Overview of graphene nanodots

7.1.2 Discovery and development of graphene nanodots

7.1.3 Unique properties and advantages of graphene nanodots

7.2 Structural and chemical characteristics of graphene nanodots

7.2.1 Quantum confinement and photoluminescence

7.2.2 Surface functionalization and biocompatibility

7.2.3 Synthesis methods: Challenges and advances

7.3 Graphene nanodots in cancer diagnosis

7.3.1 Role in early detection of cancer

7.3.2 Imaging modalities enhanced by graphene nanodots

7.3.3 Targeting cancer biomarkers with functionalized graphene nanodots

7.4 Graphene nanodots in cancer treatment

7.4.1 Photothermal therapy: Mechanism and efficacy

7.4.2 Drug delivery systems using graphene nanodots

7.4.3 Theranostics: Integrating diagnosis and treatment

7.5 Safety and biocompatibility of graphene nanodots

7.5.1 Cytotoxicity and long-term effects

7.5.2 In Vivo Studies: Biodistribution and metabolism

7.5.3 Regulatory considerations for clinical use

7.6 Future perspectives and challenges

7.6.1 Scaling up production of graphene nanodots

7.6.2 Overcoming current barriers in clinical translation

7.6.3 Potential impact on personalized cancer therapy

7.7 Conclusion

7.7.1 Summary of key findings

7.7.2 The future role of graphene nanodots in oncology

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Chapter 8 Role of polymeric nanodots in cancer diagnosis and treatment

8.1 Introduction

8.2 Types of nanodots

8.2.1 Carbon nanodots

8.2.2 Quantum dots

8.2.3 Graphene quantum dots

8.2.4 Silicon nanodots

8.3 Synthesis of nanodots

8.4 Role of nanodots in cancer diagnosis.

8.4.1 Image modalities enhanced by nanodots

8.4.2 Early detection of cancer biomarkers

8.4.3 Real-time imaging applications

8.5 Nanodots in cancer treatment

8.5.1 Drug delivery systems

8.5.2 Photothermal therapy

8.5.3 Photodynamic therapy

8.6 Multifunctional nanodots

8.6.1 Theranostic applications

8.6.2 Dual-modal imaging and treatment

8.7 Challenges and limitations

8.7.1 Scale-up challenges in manufacturing

8.7.2 Cost and economic barrier

8.7.3 Regulatory and ethical considerations

8.8 Future perspectives and trends

8.9 Conclusion

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Chapter 9 Role of carbon-based nanodots in cancer diagnosis and treatment

9.1 Introduction

9.2 Cancer pathophysiology

9.3 Current diagnostic techniques

9.4 Carbon nanodots

9.5 Synthesis of carbon nanodots

9.5.1 Hydrothermal/solvothermal method

9.5.2 Microwave-assisted method

9.5.3 Electrochemical method

9.5.4 Chemical vapor deposition

9.6 Characterization of carbon nanodots

9.6.1 Transmission electron microscopy

9.6.2 Fourier transform infrared spectroscopy

9.6.3 X-ray photoelectron spectroscopy

9.6.4 Dynamic light scattering

9.6.5 Photoluminescence spectroscopy

9.6.6 Nuclear magnetic resonance spectroscopy

9.7 Nanotechnology in cancer detection and treatment

9.7.1 Nanodiamonds

9.7.2 Graphene carbon dots

9.7.3 Fullerene

9.7.4 Carbon nanotubes

9.8 Conclusion and future direction

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Chapter 10 Nanodots for overcoming drug resistance in cancer

10.1 Introduction

10.1.1 Emerging role of nanotechnology in cancer treatment

10.1.2 Overview of nanodots: Structure, properties, and potential

10.2 Mechanisms of drug resistance in cancer

10.2.1 Efflux pumps and reduced drug accumulation

10.2.2 Alterations in drug targets.

10.2.3 DNA damage repair mechanisms.

Notes:

Description based on publisher supplied metadata and other sources.

Part of the metadata in this record was created by AI, based on the text of the resource.

Other Format:

Print version: Prajapati, Bhupendra G. Nanodots for Cancer Diagnosis and Treatment

ISBN:

9780443275128

OCLC:

1547765203