Cancer of the upper aerodigestive tract : assessment and management in people aged 16 and over / National Institute for Health and Care Excellence.

Format:

Book

Author/Creator:

National Institute for Health and Care Excellence, author, issuing body.

Series:

Clinical guideline (National Institute for Clinical Excellence (Great Britain)) ; Number 36.

NICE Guideline ; Number 36

Language:

English

Subjects (All):

Evidence-based medicine.

Neck--Cancer.

Neck.

Physical Description:

1 online resource.

Place of Publication:

London : National Institute for Health and Care Excellence, 2016.

Summary:

There is no single universal definition of the upper aerodigestive tract; for the purposes of this guideline, it encompasses the oral cavity, oropharynx, nasopharynx, hypopharynx, larynx, and paranasal sinuses. The vast majority of cancers at these sites are squamous cell carcinomas (National Head and Neck Cancer Audit, 2014). Some other cancers with less common histological diagnoses, such as mucosal melanomas of the upper aerodigestive tract, are also covered by this guideline.

Contents:

Foreword

Key research recommendations

Methodology

Pictorial representation of the diagnostic recommendations

1. Needs Assessment

1.1. Introduction

1.2. Incidence and prevalence

1.3. Risk Factors

1.4. Diagnosis and treatment

1.5. Survivorship and long-term effects of cancer treatment

References

2. Information and support

2.1. Information needs

2.2. Smoking cessation

3. Investigation

3.1. Assessment of neck lumps

3.2. Identifying the occult primary

3.3. Clinical staging - who and how?

4. Treatment of early stage disease

4.1. Squamous cell carcinoma of the larynx

4.2. Management of the N0 neck in T1-2 squamous cell carcinoma of the oral cavity

4.3. Squamous cell carcinoma of the oropharynx (T1-T2, N0)

5. Treatment of advanced disease

5.1. Squamous cell carcinoma of the larynx

5.2. Squamous cell carcinoma of the hypopharynx

5.3. Palliation of breathing difficulties

6. HPV-related disease

6.1. HPV testing

6.2. De-intensification of treatment

7. Less-common upper aerodigestive tract cancers

7.1. Carcinoma of the nasopharynx

7.2. Carcinoma of the paranasal sinuses

7.3. Unknown primary of presumed upper aerodigestive tract origin

7.4. Mucosal melanoma

8. Optimising function and rehabilitation

8.1. Enteral nutrition support

8.2. Speech and language therapy interventions

8.3. Shoulder rehabilitation

9. Follow-up of people with cancer of the upper aerodigestive tract and the management of osteoradionecrosis (ORN)

9.1. Follow-up

9.2. Management of ORN

Appendices

Appendix A. The cost-effectiveness of systemic imaging for distant metastases in patients with cancer of the upper aerodigestive tract?

Appendix B. The cost-effectiveness of initial treatments for newly diagnosed T1 or T2 carcinoma of the larynx?

Appendix C. The Cost-Effectiveness of Management Strategies for the Clinically and Radiologically N0 Neck

Appendix D. Abbreviations

Appendix E. Glossary

Appendix F. Guideline Scope

Appendix G. People and organisations involved in production of the guideline

Appendix H. Evidence Review.

Notes:

Description based on publisher supplied metadata and other sources.