Use of the electromotive drug administration system in patients with superficial bladder cancer : a review of the clinical effectiveness, safety, and cost-effectiveness / Canadian Agency for Drugs and Technologies in Health.

Format:

Book

Author/Creator:

Canadian Agency for Drugs and Technologies in Health, author, issuing body.

Series:

Rapid Response Report: Summary with Critical Appraisal

Language:

English

Subjects (All):

Cost effectiveness.

Physical Description:

1 online resource.

Place of Publication:

Ottawa (ON) : Canadian Agency for Drugs and Technologies in Health, 2014.

Summary:

Non-muscle (superficial) invasive bladder cancer accounted for about 6% of all cancers in Canada in 2008. To treat this condition, systemic drug delivery to the bladder is generally ineffective as the bladder's wall prevents therapeutic substances from diffusing through. Intravesical therapy delivers drugs through a catheter directly into the bladder and is therefore more effective, but still faces limitations resulting in the need for a high frequency of instillations among other issues. Furthermore, superficial bladder cancer has a high recurrence rate. In 2006, the condition was reported to cost

Contents:

CONTEXT AND POLICY ISSUES

RESEARCH QUESTIONS

KEY FINDINGS

METHODS

Literature Search Strategy

Selection Criteria and Methods

Exclusion Criteria

Critical Appraisal of Individual Studies

SUMMARY OF EVIDENCE

Quantity of Research Available

Summary of Study Characteristics

Summary of Critical Appraisal

Summary of Findings

Limitations

CONCLUSIONS AND IMPLICATIONS FOR DECISION OR POLICY MAKING

REFERENCES

APPENDIX 1 Selection of Included Studies

APPENDIX 2 Other References of Potential Interest (Did not meet inclusion criteria).

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.