1 option
Phase II, multicenter, randomized, double-blind, placebo-controlled, parallel group study to determine the pharmacodynamics of sodium nitroprusside during prolonged infusion in pediatric subjects / Scott Schulman, Gregory B. Hammer.
- Format:
- Book
- Author/Creator:
- Schulman, Scott, author.
- Hammer, Gregory B., author.
- Language:
- English
- Subjects (All):
- Outcome assessment (Medical care).
- Physical Description:
- 1 online resource (92 pages)
- Place of Publication:
- Bethesda, MD : Eunice Kennedy Shriver National Institute of Child Health and Human Development, 2012.
- Summary:
- A Phase II, randomized, double-blind, withdrawal to placebo study examining the efficacy, safety, and tolerability of sodium nitroprusside (SNP) in pediatric subjects. Objectives were to determine the persistence of the effect of SNP on blood pressure during stable infusion regimens lasting at least 12 hours and to assess the potential for rebound hypertension during a 30 minute blinded phase following administration of SNP for at least 12 hours when infusion is temporarily discontinued.
- Notes:
- Description based on publisher supplied metadata and other sources.
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