COVID-19. Part 2 : Origin Impact and Management / edited by Tahmeena Khan and Alfred J. Lawrence.

Format:

Book

Author/Creator:

Lawrence, Alfred J, Author.

Contributor:

Khan, Tahmeena, editor.

Lawrence, Alf J., editor.

Language:

English

Subjects (All):

COVID-19 (Disease).

Physical Description:

1 online resource (184 pages)

Edition:

First edition.

Place of Publication:

Singapore : Bentham Science Publishers Pte. Ltd., 2023.

Summary:

COVID-19 has spread like wildfire across the globe since the start of the SARS-CoV-2 outbreak, hampering quality of life at multiple levels and causing many deaths. Many aspects of the human experience have been affected, with a body of research being published on its effects on psychological and physical well being, loss of jobs, pay cuts, education, and unpaid caregiving. New findings on these aspects are still emerging as we learn more about the consequences of the pandemic. This book is intended as a simple summary of recent findings about COVID-19 for academicians and students from science, humanities and commerce backgrounds to understand the pandemic from a microscopic view and how it has touched our lives at different levels. A collection of topics is presented and explored through chapters dedicated to niche topics on COVID-19. Each chapter is authored by expert scientists, academicians and scholars from leading institutions in India. The key features of this book set are: - Interdisciplinary content, making it useful for readers from different academic streams - A blend of basic and applied research in biology, medicine and social science - A focus on findings from India - Updated References for advanced readers This collection of topics is invaluable for researchers and working professionals in industry and academia as well as general readers who want a broad, insightful perspective on COVID-19.

Contents:

Cover

Title

Copyright

End User License Agreement

Contents

Foreword I

Foreword II

Preface

List of Contributors

COVID-19 Pandemic: Outbreak, Epidemiology and Immunology

Uzma Afreen1, Ushna Afreen1 and Darksha Bano2

INTRODUCTION

HISTORICAL PERSPECTIVE

Origination of COVID-19 and Statistical Data

Morphological Features of SARS-CoV-2

The Structural Proteins:

Current Situation of COVID-19 all over the World

Mode of Infection

Mode of Transmission

Measures to Contain COVID-19

Diagnosis

1. NAATs (Nucleic acid Amplification Tests)

2. Antigen Test

3. Self-Tests

PREVENTION

1. General Measures

2. Measures adopted by Governments all over the world

Probable Medicinal Intervention

Antiviral Drugs

Antibacterial Drugs

Antimalarial Drugs

Immunomodulatory Drugs

Monoclonal Antibodies

Drug Repurposing and Computational Assessment

Vaccines and Futuristic Strategies

RNA-Based Vaccines

Viral Vector Vaccines

Protein-Based Vaccines

Inactivated Virus Vaccines

COVID-19 Vaccines for Children

CONCLUSION

CONSENT FOR PUBLICATION

CONFLICT OF INTEREST

ACKNOWLEDGEMENTS

REFERENCES

The Impact of Air Pollution and Environmental Factors on COVID-19 Transmission

Alfred J. Lawrence1, Vinay P. Aneja2 and Tahmeena Khan3,*

Facts and Figures

Structure and Activity Domain of SARS-CoV-2

The Search for Possible Medicinal Interventions

Mode of Spread

Respiratory Transmission

Transmission through Direct Contact

Transmission through Domestic Pets

Vertical Transmission

Faecal-Oral (or Fecal Aerosol) Transmission

Clinical Symptoms with Special Emphasis on Respiratory Functionalities

AIR POLLUTION AS A CONTRIBUTING FACTOR.

Studies Suggesting an Alleged Association between Air Quality and COVID-19

Is Indoor Air Pollution Neglected Here?

Pathophysiology of SARS-CoV-2 and Similarity in Mechanistic Action with Particulate Matter

Household Characteristics and their Impact

Improvement in Air Quality during the Lockdown: Exploring the Positive Aspect of the Pandemic

Contribution of Meteorological Parameters

Natural Resources as Immunity Boosters- A Probable Preventive Measure

ACKNOWLEDGEMENT

Impact Of The COVID-19 Pandemic: A Changed World

Umang Tandon1,* and Apoorva Tandon2

THE CORONAVIRUS CURVES

ECONOMIC IMPACT

Effect on the Global Supply Chain

Effect on Employment and Workforce Disparities

Effect on Tourism and Hospitality

Effect on the IT Industry

Impact of COVID-19 Pandemic on Women

Tahmeena Khan1, Saima Arif2,3 and Alfred J. Lawrence2,*

COVID-19 and its Impact

Effect of COVID -19 Pandemic on the Human Race

Women and COVID 19

Women and Health and Hygiene

Reproductive Health

Psychological Health

Nutritional Aspects Concerning Women's Health

The Impact of the Pandemic on Indian Women

A SURVEY-BASED STUDY WITH WOMEN

RESULTS AND DISCUSSION

Demographic Details

Employment Details

Physical Fitness and Nutritional Aspects

Sanitary and Hygiene Practices

CONCLUDING REMARKS

Vaccination Hesitancy and Adaptation with Particular Emphasis on Women

Tahmeena Khan1, Alfred J. Lawrence2,*, Amos Nascimento3 and Rohan Srivastava1

A QUESTIONNAIRE-BASED STUDY

RESULTS AND DISCUSSION.

Demographic Details

COVID-19 Vaccine Awareness

Safety Concerns Related to Vaccination

Misconceptions and Disbeliefs

Computational Drug Discovery Against COVID-19

Shristi Modanwal1, Viswajit Mulpuru1 and Nidhi Mishra1,*

VIRTUAL SCREENING METHODS

Structure-Based Virtual Screening

Protein-Ligand Docking

Structure-Based Pharmacophores

Ligand-Based Virtual Screening

Similarity Method

Pharmacophore Mapping

Machine Learning Method

Combined LBVS and SBVS

INTERPRETING DRUG INTERACTION

APPLICATION OF VIRTUAL SCREENING FOR COVID 19 THERAPEUTICS

FUTURE PROSPECTS OF VIRTUAL SCREENING

Methods in Drug Repurposing: Emphasis on COVID-19

Akhilesh Kumar Maurya1 and Nidhi Mishra1,*

Drug Repurposing Methods

Computational Methods

Structure-Based

Artificial Intelligence-Based

Pathway-Based and Genetic Associations

Experimental Approaches

Targeted Based Approaches

SARS-CoV-2 Drug Repurposing

Drug Repurposing Molecules for COVID-19

Remdesivir

Ribavirin

Darunavir

Chloroquine

Hydroxychloroquine

Dexamethasone

Emapalumab and Sarilumab

Computational Study

Virtual Screening of Phytochemicals in Search of a Potential Drug Candidate for COVID-19: DFT Study and Molecular Docking

Nikita Tiwari1,*, Lubna Jamal1 and Anil Mishra1

MATERIALS AND METHODS

DFT Calculations

Molecular Docking

RESULT AND DISCUSSION

DFT Calculation Studies

Thermodynamic Properties

Molecular Orbital Properties.

Binding Affinity and Binding Interactions Analysis

Role of Immunity Against COVID-19

Nidhi Singh1,*

Immune System: Process and Defense

Creation of Barriers for the Prevention of Pathogens

Identification of Pathogens After their Entry

Elimination of Pathogens

Generation of Immunological Memory

STRUCTURE OF SARS-COV-2

Immunopathogenesis of COVID-19

Non-Severe Stages

Severe Stage

NUTRITION AND IMMUNITY

Vitamin A and Immunity Efficiency

Vitamin C and Immunity Efficiency

Vitamin D and Immunity Efficiency

Zinc Micronutrient and Immunity Efficiency

Copper Micronutrient and Immunity Efficiency

HERD IMMUNITY AND CORONAVIRUS

NATURAL PRODUCTS AND IMMUNITY AGAINST COVID-19

Tulsi as Immunity Booster

Giloy as Immunity Booster

Ashwagandha as Immunity Booster

Dalchini as Immunity Booster

Sunthi as Immunity Booster

Marich as Immunity Booster

VACCINATION AND IMMUNITY AGAINST COVID-19

Subject Index

Back Cover.

Notes:

Includes bibliographical references.

Description based on publisher supplied metadata and other sources.

Description based on print version record.

ISBN:

9789815165944

9815165941

OCLC:

1382694281