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Issues in kidney disease : chronic kidney disease / Stephen Z. Fadem and Samaya Javed Anumudu, editors.
- Format:
- Book
- Series:
- Issues in Kidney Disease
- Language:
- English
- Subjects (All):
- Nephrology.
- Kidneys--Diseases.
- Kidneys.
- Physical Description:
- 1 online resource (442 pages)
- Place of Publication:
- New York, New York : Nova Science Publishers, [2021]
- Summary:
- "Issues in Kidney Disease - Chronic Kidney Disease (CKD) is a collection of 17 detailed chapters written by world leaders and experts in nephrology in order to provide a comprehensive review of kidney disease using evidence-based recommendations and guidelines. This book starts with an excellent introduction and classification of CKD and progresses into various important aspects of CKD care including prevention, diabetes, hypertension, acid-base disturbances, genetic and age considerations, glomerulonephritis, interstitial nephritis, aging, as well as considerations for patients in pregnancy and with malignancy. This book will appeal to trainees and practicing clinicians in internal and family medicine, as well as nephrology, who would like current and practical clinical knowledge of chronic kidney disease to help improve the lives of patients with this condition"-- Provided by publisher.
- Contents:
- Intro
- Contents
- Foreword
- Preface
- References
- Acknowledgments
- Editors' Contact Information
- List of Contributors
- Chapter 1
- Introduction and General Principles of Chronic Kidney Disease
- Abstract
- Introduction
- Definition of Chronic Kidney Disease
- Epidemiology
- Clinical Manifestations of CKD
- A Holistic Approach to the Patient with CKD
- Chapter 2
- Classification of Kidney Diseases
- Definition and Classification of Kidney Diseases
- Classification Based on Temporal Presentation
- Classification Based on Pathology
- Glomerular Diseases
- Diseases Involving Podocyte Number and Dynamics
- Diseases Involving Mesangial Expansion or Infiltration
- Monoclonal Gammopathies of Renal Significance
- Diseases Resulting from Glomerular Basement Membrane Abnormalities
- Diseases Resulting from Endothelial Injury
- Tubulointerstitial Diseases
- Tubulointerstitial Diseases Caused by Inflammation
- Categorization According to Dominant Cell Types within Infiltrates
- Tubulointerstitial Diseases with TBM deposits
- Non-Inflammatory Sources of Tubulointerstitial Injury
- Cystic Kidney Diseases and Genetic Etiologies of Tubulointerstitial Damage
- 'Secondary' Tubulointerstitial Injury
- Vascular Diseases
- Vasculitis
- Thrombotic Microangiopathy
- Non-Vasculitic Large Vessel Diseases
- Classification of Renal Allograft Pathology
- Antibody-Mediated Rejection
- T-Cell Mediated Rejection
- Vascular Rejection
- Classification of Polyomavirus Nephropathy/Nephritis
- Other Infections Occurring in the Setting of Transplantation
- Chapter 3
- Diagnostic Studies in Kidney Disease
- 1. Kidney, Ureter, Bladder and Angiography
- 1.1. X-Rays
- 1.2. Computed Tomography
- 1.3. Fluoroscopy
- 1.4. Renal Angiography.
- 2. Computed Tomography
- 3. Ultrasonography
- 4. Magnetic Resonance Imaging (MRI) in Chronic Kidney Disease
- 5. Blood oxygen Level-Dependent/Functional Magnetic Resonance Angiography
- 5.1. Limitations
- 6. Positron Emission Tomography
- Chapter 4
- Reverse the Reversible
- Approach
- The Serum Creatinine
- Analytical Variation
- Biological Variation
- Muscle Mass
- Food Consumption - Meats
- Tubular Secretion
- Monoclonal Gammopathy
- Interference with the Picric Acid Test
- Model Car Fuel Ingestion
- Hemodynamics
- Autoregulation
- Hypertension: Afferent Arteriolar Thickening vs. Overwhelming Autoregulation Autoregulation Impairment
- Afferent Arteriolar Thickening
- Overwhelming Autoregulation
- Autoregulation Impairment
- Dehydration
- Exercise Intensity
- Diuretics
- Heart Failure
- ACEi-ARB Therapy
- Non-Steroidal Anti-Inflammatory Drugs (NSAIDS)
- Acute Febrile Illness
- COVID-19
- Obesity
- Psychological Stress
- Acute Kidney Injury
- Rhabdomyolysis
- Contrast Induced Nephropathy (CIN)
- Recent Hospitalization
- Nephrotoxins
- Anabolic Steroids
- Underlying Disease Exacerbation
- Urinary Tract Infection
- Obstructive Uropathy
- Conclusion
- Chapter 5
- Prevention of Chronic Kidney Disease - An Overview
- Which Serum Creatinine Should We Believe?
- Patterns of Kidney Disease Progression
- Treat the Underlying Condition
- Measures to Prevent CKD Progression
- Hypertension
- APOL1
- White Coat Hypertension
- Nocturnal Changes in Blood Pressure
- Management Principles
- Diabetes
- Intensive Control
- SGLT2 Inhibition
- Finerenone
- Metformin
- Converting Enzyme Inhibitor (ACE) or Angiotensin Receptor Blockade (ARB) Therapy (NOT both)
- Metabolic Acidosis - Fruits, Vegetables, Bicarbonate Tablets.
- Low-Protein Diet Should Be Replaced with the Plant-Dominant Low-Protein Diet (PLADO)
- Avoid Toxic Medications
- Control Albuminuria
- Control Obesity
- Salt Restriction
- Dietary Phosphorus Restriction
- Hyperlipidemia/Statin Use
- Uric Acid
- Antioxidants and Vitamins
- Reducing Oxidative Stress through Diet
- Cigarette Smoking
- Exercise
- Chapter 6
- Anemia in Chronic Kidney Disease
- Clinical Pearls
- HIF
- Red Blood Cells
- Recombinant Erythropoietin
- Quality of Life (1989)
- Dialysis Outcomes Quality Initiative (DOQI) Guidelines
- Normal Hematocrit Study
- Darbepoetin (2001)
- Extended Dosing
- EPO Hyporesponsiveness (2002)
- Safety Concerns with ESA Use [20]
- Correction of Anemia and Reversibility of Heart Disease
- CHOIR
- TREAT
- Polyethylene Glycol - Epoetin
- Iron
- Iron Replacement Therapies
- Ferric Citrate
- Ferrous Salts
- Imferon - Iron Dextran
- Dexferrum Iron Dextran
- INFeD Iron Dextran
- Sodium Ferric Gluconate
- Venofer
- Ferumoxytol
- Effects of Iron
- Inflammation
- Infection
- Serious Hypersensitivity Reactions
- Hemoglobin
- Mitochondria
- Transferrin and Ferritin
- Evaluation of Anemia of CKD
- Blood Clotting
- Platelets
- The Extrinsic Pathway - The Fibrin Clot
- The Intrinsic Pathway
- The Common Pathway
- Inhibitors of Coagulation
- Plasmin
- Fibrinolysis
- The Kinin System [53]
- Chapter 7
- Metabolic Acidosis in Kidney Diseases
- Normal Kidney Physiology in the Setting of Metabolic Acidosis
- Associations between Kidney Disease and Metabolic Acidosis
- Chronic and Systemic Effects of Metabolic Acidosis
- Treatment of Metabolic Acidosis in Chronic Kidney Disease
- Medical Therapy
- Dietary Modifications
- References.
- Chapter 8
- Hypertension in Chronic Kidney Disease
- Consequences of Hypertension
- Pathogenesis of Hypertension in CKD
- Diagnosis
- Blood Pressure Measurement
- Blood Pressure Variability
- Nocturnal Pattern
- Masked Hypertension
- Treatment
- Non-Pharmacological Measures
- Sodium
- Potassium
- DASH Diet
- Alcohol
- Stop Interfering Substances
- Effectiveness of Non-Pharmacological Interventions
- Level and Drug Choice
- Pharmacotherapy
- Renin Angiotensin System Blockade
- Thiazide and Thiazide-Like Diuretics
- Calcium Channel Blockers
- Second-Line Drugs
- Newer Agents
- Combination Choice
- Device Therapy
- Patient Populations
- Intensive BP Lowering
- Non-Diabetic CKD
- Diabetic CKD
- Advanced CKD
- Dialysis
- Peritoneal Dialysis
- Hemodialysis
- Which BP Measurement to Use?
- Minimizing Dietary Sodium Intake
- Maximizing Dialytic Sodium Removal
- Transplantation
- Guidelines and Variability
- Research Needs
- Chapter 9
- The Approach to Hematuria in Chronic Kidney Disease
- History
- Physical Examination
- Laboratory Studies
- Urinalysis
- Urine Centrifuge and Phase Contrast Microscopy Evaluation
- Urinary Protein and Albumin Quantification
- Urine Culture
- Urine Cytology
- Blood Laboratory Studies
- Imaging Workup
- Computed Tomography (CT Urography)
- Ultrasound (US)
- Magnetic Resonance Imaging (MR Urography)
- Urologic Workup
- Cystoscopy
- Ureteroscopy
- Kidney Biopsy
- General Management and Follow Up
- Selected Causes of Hematuria
- Acquired Cystic Kidney Disease (ACKD)
- Anticoagulant-Related Nephropathy
- Renal Arteriovenous Malformation (AVM)
- Loin Pain Hematuria Syndrome
- Chapter 10.
- The Approach to Glomerular Disease in Chronic Kidney Disease
- Albumin
- Kidney Function
- Other Laboratory Tests
- The Role of Genetic Testing
- Imaging Studies
- Renal Ultrasound
- Vascular Doppler Study, CT Angiography and MR Angiography
- Therapy
- BP Control and RAAS Blockers
- Salt Restriction and Diuretics
- Sodium Glucose Cotransporter 2 (SGLT2) Inhibitors
- Lipid Management
- Anticoagulation
- Vaccination and Prophylaxis
- Immunosuppressive Treatment
- Glucocorticoids
- Calcineurin Inhibitors (CNI)
- Cyclophosphamide (CYC)
- Mycophenolate Mofetil (MMF) and Mycophenolic Acid (MFA)
- Azathioprine (AZA)
- Adrenocorticotropic Hormone (ACTH)
- Rituximab
- Plasma Exchange
- Selected Glomerular Diseases
- Focal and Segmental Glomerulosclerosis (FSGS)
- Minimal Change Disease (MCD)
- Membranous Nephropathy (MN)
- IgA Nephropathy
- Infection-Related Glomerulonephritis (IRGN)
- Pauci-Immune Glomerulonephritis (GN)
- Anti-GBM Disease
- Membranoproliferative Glomerulonephritis (MPGN)
- Diabetic Nephropathy
- Lupus Nephritis (LN)
- Monoclonal Gammopathy of Renal Significance (MGRS)
- Amyloidosis
- End-Stage Kidney Disease in Glomerular Diseases
- Kidney Replacement Therapy in Glomerular Diseases
- Kidney Transplantation in Glomerular Diseases
- Chapter 11
- Mechanisms of Disease
- Hyperfiltration and Autoregulation
- Endothelial Cell Dysfunction
- TGFß
- Angiotensin II (AII)
- The Podocyte
- Natural History and Timeline
- Principles of Management
- Intensive Diabetes Control
- Continuous Glucose Monitoring
- Selected Medications
- SGLT2 Inhibition.
- Glucagon-Like Protein-1 (GLP1) Receptor Agonists.
- Notes:
- Description based on print version record.
- Includes bibliographical references and index.
- ISBN:
- 1-68507-124-4
- OCLC:
- 1268122677
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