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Signaling pathways of the immune system / edited by Kenan Demir and Mustafa Usanmaz.

EBSCOhost Academic eBook Collection (North America) Available online

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Format:
Book
Contributor:
Demir, Kenan, editor.
Usanmaz, Mustafa, editor.
Series:
Immunology and Immune System Disorders Series
Language:
English
Subjects (All):
Cellular immunity.
Physical Description:
1 online resource (184 pages)
Edition:
1st ed.
Place of Publication:
New York : Nova Science Publishers, [2023]
Summary:
"This book examines the issue of immunity with the signaling pathways it is associated with, which has come to the fore again with the COVID-19 pandemic. Our book provides an opportunity to have an overview of the signaling pathways involved in the function of cells in the immune system with the latest developments and recent studies on the subject to the reader"-- Provided by publisher.
Contents:
Intro
Contents
Preface
Chapter 1
Introduction to Signaling Pathways
Abstract
Introduction
Signaling Pathways and Proteins
Signaling Pathways, Receptors, and Immunity
The Hippo Pathway
Cell Signaling Systems
Cell-Signaling and Autoimmunity
Conclusion
References
Chapter 2
Toll Like Receptor (TLR) Signaling Pathways
TLR Family, Structure, Localization and Features
Signaling of TLR
MyD88-Dependent Pathway
MYD88-Independent (TRIF-Dependent) Pathway
Relationship of Non-Coding RNAs and Toll-Like Receptors
Chapter 3
The FGF Signaling Pathway and Immune System
Innate Immune Response and FGF Pathway
Adaptive Immune Response and FGF Pathway
FGF Pathway, Inflammatory Processes and Autoimmune Diseases
Multiple Sklerosis (MS), Experimental Autoimmune Encephalomyelitis (EAE)
Psoriasis
Autoimmune Hyperphosphatemic Calcinosis, Graves' Disease, Type 1 Diabetes Mellitus
Transplant Rejection
Immune Complex Formation and Immune Cytotoxicity
Allergic Reactions
Immunotherapy and Immunomodulation
Chapter 4
Adipokines and Insulin Signaling Pathways
Adipokines
Insulin Signal Pathways
The Normal Insulin Signaling Pathway
Insulin-Dependent Glucose Uptake Signaling
Protein Kinase B(PKB)/Akt and Insulin Signaling Pathway
PHAS-I Phosphorylation and Insulin
mTOR Phosphorylation and Insulin
IGF-I Signaling Pathway and Insulin
Leptin
Adiponectin
Retinol-Binding Protein-4
Resistin
Omentin
Vaspin
Visfatin
Apelin
Asprosin
Adipsin
Chemerin
Tumour-Necrosis Factor-α (TNF-α)
Interleukin-6 (IL-6)
Chapter 5.
Chemokine Signaling Pathway
Structure of Chemokines
Chemokine Receptors
Production, Functions, and Signaling Pathways of Chemokines
Chapter 6
TNF Superfamily Pathway
TNF and Receptors
TNF Superfamıly
TNF Signal Transmission: Apoptosis - Inflammation Mechanisms
Biological Effects of TNF
TNF and Cancer
Chapter 7
T Cell Activation Signaling Pathways
T Cells Activation
TCR Complex
Costimulatory Signals of CD28
T Cells Differentiation
CD8+ Cytotoxic T Cells
CD4+ T Helper Cells
Chapter 8
Tumour-Derived Exosome (TEX) Mediated Immune Suppression
Exosomes
Exosome Biogenesis
Exosomal Content
Tumour-Derived Exosomes (TEXs)
Mechanisms of TEX-Mediated Immune Suppression
Chapter 9
Inflammasome Pathways
Canonical Inflammasome Sensors
NLRP3 (Cryopyrin, NALP3)
NLRC4
NLRP1
AIM-2
Pyrin
Non-Canonical Inflammasome Sensors
Adaptors
Effectors
Alternative Inflammasome Pathway
Chapter 10
Natural Killer Cell Receptors: Human Target Cell - NK Cell Ligand-Receptor Interactions
NK Cell Activating Receptors and Malignant Melanocytes Ligands
NK Cell Inhibitory Receptors and Malignant Melanocytes Ligands
NK Cell and Melanoma Microenvironment
Modulating NK Cell Activity as a Therapeutic Strategy in Melanoma Patients
Chapter 11
B Cell Activation Pathways
Stages in B Lymphocytes Developmental Pathway
B Lymphocytes Development in Bone Marrow.
B Lymphocytes Development in Secondary Lymphoid Tissues
B Lymphocytes Terminal Differentiation
Germinal Center Reactions
B Cell Activation Pathway
B Cell Activation and BCR Signaling
B Cell Activation by T Cell-Independent Pathway
B Cell Activation by T Cell-Dependent Pathway
B Cell Activation and Tolerance
Index
Editors' Contact Information
Blank Page.
Notes:
Includes bibliographical references and index.
Description based on print version record.
Other Format:
Print version: Demir, Kenan Signaling Pathways of the Immune System
ISBN:
9798886976816
OCLC:
1374426716

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