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Photosensitizers and their applications / Davor Margetic and Renjith Thomas, editors.

EBSCOhost Academic eBook Collection (North America) Available online

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Format:
Book
Contributor:
Margetic, Davor, editor.
Thomas, Renjith, editor.
Series:
Materials science and technologies series.
Materials science and technologies series
Language:
English
Subjects (All):
Clinical biochemistry.
Photochemistry.
Photosensitizing compounds.
Physical Description:
1 online resource (368 pages)
Place of Publication:
New York : Nova Science Publishers, Inc., [2022]
Summary:
"Application of light in chemistry presents an active field of research with a very promising outlook, particularly in technology and medicine. Molecules which mediate the transfer of light to another molecule (photosensitizers) are the cornerstone of exploitation of light. The current state of research and recent progress in applications of photosensitizers in diverse fields are documented in twelve chapters written by scientists from around the world. Chapter 1 gives a general overview on the applications of photosensitizers in synthetic organic chemistry. This review is followed by Chapters 2-7, which deal with the various applications of photosensitizers in medicine, in particular for photodynamic cancer therapy. The subsequent Chapters 8-12 cover different aspects of applications of photosensitizers in material science, such as for dye-sensitized solar cells and photo-responsive materials"-- Provided by publisher.
Contents:
Intro
Contents
Preface
Chapter 1
Photosensitizers in Organic Synthesis
Abstract
Introduction
Photosensitizers and Energy Transfer
Photosensitized Reactions of Alkenes, Isomerization and Addition
Formation of Three-Membered Rings
Formation of Four-Membered Rings
Formation of Five- and Six-Membered Rings and Larger Rings
Diastereoselective and Enantioselective Photosensitized Reactions
Conclusion
Acknowledgment
References
Chapter 2
Photodynamic Therapy: Fundamentals, Mechanisms and Its Applications against Osteosarcoma
General aspects of Cancer
Osteosarcoma
Photodynamic Therapy: Concepts and Mechanism
Modes of Cancer Cells Death in a Photodynamic Protocol
Recent Advances of Photodynamic Therapy against Osteosarcoma (2010-2020)
In Vitro Studies (2010-2020)
In Vivo Studies (2010-2020)
Clinical Evaluation
Chapter 3
Tumor-Selective and Self-Activating Chemiluminescent Photosensitizers for Photodynamic Therapy
Introduction to Photodynamic Therapy
Introduction to Chemiluminescent and Bioluminescent Systems
Chemiluminescence
Bioluminescence
Applications for Chemiluminescence and Bioluminescence in PDT
CL-Based PDT Systems
BL-Based PDT Systems
Alternatives to Conventional CL/BL-Mediated PDT
Acknowledgments
Chapter 4
Fluorescent Photosensitizers: A Promising Tool for Biomedicine
Fluorescent Photosensitizers in Photodynamic Therapy
Fluorescence Photosensitizers in Live Cell Imaging
Chapter 5
Emerging Trends in Nanomaterials for Photodynamic Therapy Applications: The Current Scenario
Mechanism of Photodynamic Therapy
Type I Mechanism.
Type II Mechanism
Photosensitizers
Application of Nanomaterials in PDT
Liposomes
Polymeric Nanomaterials
Viral Nanoparticles (VNPs)
Carbon Nanotubes
Fullerenes
Magnetic Nanoparticles
Quantum Dots
Silver Nanoparticles
Gold Nanoparticles
Silica Nanoparticles
Application of PDT
Cancer Therapy
Antimicrobial Photoinactivation Therapy
Chapter 6
Synthesis of Pheophorbide a and Chlorin e6 Photosensitizers
Isolation from Natural Sources and Semisynthesis
Reactions on E Ring of Pheophorbide a
Reactions on Vinyl Position of Pheophorbide a
Reactions on Meso Positions of Pheophorbide a
Functional Derivatizations of Chlorins
Direct Amide Preparations from Chlorins
Synthesis of Metal Complexes
Pyropheophorbide Derivatizations
Conslusion
Chapter 7
Photosensitizers and Their Applications in China
The Discovery of New Photosensitizers in China
Photosensitizers Approved by NMPA
HiPorfin
Hemoporfin (Hematoporphyrin Monomethyl Ether, HMME)
Aminolevulinic Acid Hydrochloride for Topical Powder (5-ALA)
Photosensitizers in Clinical Trials
Photocyanine
Deuteporfin
Sinoporphyrin Sodium
Photosensitizers in Research
Porphyrin-Type Photosensitizers
Chlorin-Type Photosensitizers
Bacteriochlorin
Phthalocyanine
BODIPY
The Applications PDT in China
Cancer
Recommended Protocols
Nasopharyngeal Carcinoma are as Follows [60]
Liver Carcinoma are as Follows [60]
Port Wine Stains
Recommended Protocols for PWS are as Follows [62, 63]
Condyloma Acuminatum
Intracavitary CA are as Follows [66]
External Genitalia and Perianal CA are as Follows [65]
Age-Related Macular Degeneration
Actinic Keratosis.
Bacteria-Resulted Diseases
Disinfection of Blood Products
Other Diseases
Chapter 8
Porphyrin-Based Photosensitizers for Dye-Sensitized Solar Cell Applications
Natural Dyes - Nature Creates Its Own Light Harvesting Molecules
Synthetic Dyes - Mimicking the Nature
Peripheral Modifications/Donor-Acceptor Moieties
Metallation
Nanohybrids/Co-Sensitization Strategies
Chapter 9
Recent Studies on the Performance of Sensitizers for Efficient Dye-Sensitized Solar Cells: From Dynamics to Kinetics of the Photovoltaic Processes
Acronyms
Natural Dyes
Metal-Free Organic Dyes
Computational Chemistry
The Effective Factors on the Efficiency of DSSCs
The Strong Electron Donor/Acceptor Effect
The Effect of the Extended (-Conjugated System
The Effect of the Number of Anchor Groups
The Effect of the Auxiliary Donor/Acceptor
The Effect of Different Substituted Groups
Solvent Effects
Chapter 10
Present and Future Perspectives of Photo-Responsive Molecularly Imprinted Polymers
Stimuli-Responsive Molecularly Imprinted Polymers
Conventional PR-MIPs
PR-MIPs
Bulk Polymerization
Precipitation Polymerization
Sol-Gel Method
Atom Transfer Radical Precipitation Polymerization
Surface Molecularly Imprinted Polymers
Conclusion and Perspectives
Chapter 11
Pyrene-Based Photosensitizers and Their Applications
Photodynamic Therapy
Photocatalysis
Chapter 12
Ruthenium Complexes in Dye-Sensitized Solar Cells: Experimental and Theoretical Perspectives
Components and Assembly of DSSCs [15-20, 53].
Working Principle [17, 21-22]
Incident Photon to Current Conversion (IPCC)
Development of Dyes
Metal Complex Dyes
Ruthenium Metal Complex Dyes
N3/N719/N712 Dyes
Ruthenium Dye (N3) Adsorbed on a TiO2 Brookite Cluster
Ruthenium Phenanthroline Complexes
π-System Extension (N945, Z910, K19, N719, Z907, K8, K9)
RuHDA1, RuHDA2, RuHDA3
Amphiphilic Dyes with Alkyl Chains
Different Anchoring Groups
CYC-B1
π-Extended Ferrocene
Porphyrin-Based Sensitizers
N3 dye Adsorption onto TiO2
Ru dye (N3 and chlorinated forms) and X-, X2- (X = Br, I, At)
Anatase TiO2 (1 0 1) Surface Doped with Ruthenium
Stability of Ruthenium/Organic DSSC
New Ru Complex DSSC by BCL Approach
About the Editors
Index
Blank Page
Blank Page.
Notes:
Description based on print version record.
Includes bibliographical references and index.
Other Format:
Print version: Margetic, Davor Photosensitizers and Their Applications
ISBN:
9798886970395

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